Change in the "O' serotype of Pseudomonas aeruginosa after lysogenisation with bacteriophages.
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Biomedical subjects
Publications and source records attributed to K Prakash.
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In a prospective controlled study the anti-infective properties of breast-milk were evaluated in 70 high-risk low-birth-weight infants. 32 babies (group I) were given fresh expressed breast-milk during the day and milk formula at night. 38 infants (group II) received only milk formula and served as controls. The two groups were matched for other factors that could influence the occurrence of infection. The incidence of infections was significantly less (p < 0.01) in babies who received breast-milk.
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A controlled field trial of a modified vaccine containing Salmonella typhi, TY 2 strain, in a dose of 400 x 10(9) killed organisms per capsule, was carried out in schoolchildren aged 6-17 years. The children were followed up for 6-8 months. There were 66 cases of typhoid fever in the vaccine group (7312 children) and 54 in the control group (7292 children who had received a placebo). This difference is not statistically significant. The results confirm that, as found in earlier trials, oral typhoid vaccine, in the dosages used so far, gives no protection.
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A field trial was carried out with a vaccine containing 300x10(9) killed S. typhi (strain Ty58) per tablet. A total of 12 564 children aged 1-15 years were given 3 tablets of the vaccine or a placebo at the rate of one tablet on each of 3 consecutive days. The results indicated that the vaccine, in its present form and at this dosage, gives no protection.
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