Search PubMed⌕ Search

Biomedical subjects

K Peter

Publications and source records attributed to K Peter.

At least 307 records · Page 17Linked to original sources
PubMed1975

[Behavior of the metabolism in gastric patients during a 4-day-long postoperative complete parenteral feeding with amino acids and a glucose-levulose-xylitol combination solution].

In a clinical study we tested the following parameters: free fatty acids, beta-hydroxybutyrate, acid-base-balance, lactate, bilirubin, uric-acid, fructose, xylitole, glucose in blood and urine. The tests were executed in 9 patients who were undergoing stomac operations. The cardio pulmonary system of all patients was normal, and there was a homeostasis in water and electrolytes preoperatively. In combination with the amino-acids we received a ratio of 1:1:1 for glucose, levulose and xylitole. Totally, the patients received 0.36 g per kg body weight and per hour of carbohydrates. Beta-hydroxybutyrate, aceto-acetat, and free fatty acids show normal values under conditions of parenteral nutrition as well as lactate, uric acid, and acid-base-balance. The ratio of the different carbohydrates in serum and urine prove that the infusion time and volume were extremely favourable. The loss of carbohydrates in urine was very low.

Acid-Base Equilibrium↗
PubMed1975

[Improvement of parenteral feeding through the additional administration of a serum protein solution].

On 7 days - 5 postoperative - patients undergoing Billroth I or Billroth II were continuously infused apparatively witn an amino acid mixture of 100% and a glucose-xylitol-solution of 25% (group I). One group (group II) additionally received a serum protein solution. From the first preoperative day to the fifth day of the postoperative period we determined individual parameters in blood and urine. A decrease of serum phosphate level beginning on the first day after starting parenteral nutrition was observed. In the nitrogen balances, in total protein and albumin concentration there were no differences, but serum gamma-globulin concentration of group II was very low at the end of the parenteral nutrition period, a point which at present cannot be explained.

Blood Proteins↗
PubMed1975

[The effect of various electrolyte solutions on the water and electrolyte balance during the postoperative phase].

Investigations with 3 electrolyte solutions having different qualitative and quantitative compositions were carried out to see their effect on the physiological equilibrium in the pre, intra- and postoperative phases in patients who had to undergo moderately severe surgery. On the basis of electrolyte and osmolarity determinations in serum and 24-hour urine, blood gas analyses, determinations of hemoglobin and hematocrit, 24-hour volume and specific weight of the urine, it was possible to establish an electrolyte administration adapted to the pre-, intra- and postoperative condition of the patients. By the infusion of a solution with this electrolyte content it was possible to keep the measured parameters within the normal range throughout the entire period of measurement before, during and after the operation.

Acid-Base Equilibrium↗
PubMed1975

[The reaction of the cardio-circulatory system during the introduction of the modificated NLA (AUTHOR'S TRANSL)].

The hemodynamic effects of Etomidate are examined during the introduction of a modificated NLA. The following parameters are registrated: Heart Rate, Arterial and Mean Arterial Pressure, Pulmonary and Mean Pulmonary Pressure, and Cardiac Output. The Total Periphere Resistance and the Tension-Time-Index are calculated. Apart from a short moment during and immediately after intubation a remarkable constancy of all parameters is found. The alpha-receptor-blocking effect of Etomidate and DHB and the resulting decrease of the Total-Periphere Resistance are compensated by infusion of a colloidsolution. Myoclonias are not observed. Etomidate may be regarded as a drug with few effects on the circulation. It may be thinkable, that by means of Etomidate even in shock a careful introduction is possible.

Adult↗
PubMed1975

[Circulatory changes during preoperative isovolaemic haemodilution with a mixed solution of hydroxyethyl starch and 5% human albumine. A clinical study (author's transl)].

The influence of preoperative isovolaemic haemodilution on the circulation was examined in a clinical study. Heart rate, mean arterial pressure, mean pulmonary arterial pressure, cardiac output as well as haemoglobin and haematocrit values were determined. Stroke volume, total peripheral resistance, and the modified tension-time-index were calculated. A mixture of human albumin 5% and hydroxy-ethyl-starch was used as a solution for dilution. During the dilution phase the cardiac output increased compensatorily to the decrease of haemoglobin and the haematocrit values. While the heart rate and the mean arterial pressure remained unchanged the total peripheral resistance was reduced. Considering the described conditions and contraindications, preoperative isovolaemic haemodilution is a suitable method to replace an intraoperative blood loss of up to 2000 ml autologously. Thus a posttransfusion hepatitis can be avoided. In addition, preoperative isovolaemic hemodilution improves the microcirculation and may have a prophylactic effect on the thrombosis in the postoperative phase.

Blood Circulation↗
PubMed1975

[The influence of hydroxyethyl starch on blood clotting (author's transl)].

It has been shown in clinical experiments that blood coagulation was delayed by Dextran 60 and Hydroxyethylstarch (HAS). During the postoperative period up to the 2nd postoperative day the measured clotting factors were decreased within the physiological range. Platelet adhesiveness was mainly reduced in the group of Dextran 60 and in the male Hydroxyethylstarch group. A similar effect of haemodilution as seen by haematocrit and blood viscosity results was produced by Dextran 60 and Hydroxyethylstarch. In the electrolyte group the values obtained did not show any significant influence on blood coagulation apart from a light and temporary trend to hypercoagulation during the day of operation.

Adult↗
PubMed1975

[Metabolic behavior in total parenteral nutrition during the postoperative phase].

In patients who had undergone gastric operation, total postoperative parenteral nutrition was effected using a combination of two infusion solutions having complementary constituents. 80 g L-amino acids and about 2,500 kcal in the form of a glucose-levulose-xylitol mixture together with electrolytes and trace elements were infused daily. Metabolic parameters, serum levels and the concentrations of the most important administered substances excreted in the urine were determined every day at the same time. The 1:1:1 glucose-levulose-xylitol ratio of the caloric carrier proved to be a favourable combination with respect to metabolic behaviour and the necessary daily supply of calories. The basic electrolyte requirement of the patients was to a large extent met by the quantities contained in the solutions.

Acid-Base Equilibrium↗