Hereditary spherocytosis and glucose-6 phosphate dehydrogenase deficiency.
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Biomedical subjects
Publications and source records attributed to K Pavithran.
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A case of tuberculous adenitis presenting as thrombocytopenic purpura is reported with a brief review of the literature.
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A middle-aged male with lepromatous leprosy developed bouts of skin lesions of depigmented macules and patches of vitiligo, just following attacks of type II lepra reaction each time. In view of the present concept of autoimmunity playing a role in the pathogenesis of vitiligo as well as lepra reaction, their association in our patient appears to be more than fortuious. The depigmented macules persisted even after regression of skin lesions of leprosy following chemotherapy. The vitiligo macules responded partially to topical and systemic psoralen therapy.
Among 25 patients who had short-course multidrug therapy as recommended by the WHO for paucibacillary leprosy, 3 were observed to develop relapse of their disease 8 to 12 months after completion of treatment. These three cases of relapse are reported in detail. The duration of chemotherapy recommended by the WHO in paucibacillary cases appears to be too short.