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K P Price

Publications and source records attributed to K P Price.

11 recordsLinked to original sources

Headache.

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Autonomic Nervous System

Trait levels of anxiety and psychological responses to stress in migraineurs and normal controls.

Compared migraine headache suffers and matched normal controls on the Zung Depression Inventory, Eysenck Personality Inventory, Spielberger Trait Anxiety Inventory, Taylor Manifest Anxiety Scale and the Health Locus of Control. In addition Ss viewed a film of a subincision ceremony and completed a post-film questionnaire. Migraineurs scored significantly higher than the controls on the TMAS, STAI and EPI Lie scale and rated the subincision film as significantly less unpleasant than did the controls. These results confirm earlier reports that migraineurs have higher levels of trait anxiety than normals and support the traditional description of migraineurs as inhibiting the expression of their feelings.

Anxiety

Effects of clonidine on 24-hour hormonal secretory patterns, cardiovascular hemodynamics, and central nervous function in hypertensive adolescents.

To assess the potential of antihypertensive drugs for interference with somatic growth and sexual development in hypertensive children, the effect of clonidine therapy on various endocrine, cardiovascular, and neuromuscular functions has been examined in five male adolescents with idiopathic hypertension. In studies done before and at the end of 4 weeks of twice-daily clonidine therapy, in an average daily dose of 0.31 mg, no significant effects were noted in the secretory patterns of growth hormone, luteinizing hormone, follicle-stimulating hormone, prolactin, cortisol, aldosterone, or testosterone, measured in blood obtained every 20 minutes for 24 hours. In blood obtained while the patients were supine and then erect, plasma renin activity and norepinephrine levels were significantly lowered after clonidine therapy. Cardiovascular responses to dynamic exercise were little altered beyond a 17% decrease in maximal oxygen consumption. The performance of fine motor skills was minimally altered. These data provide preliminary evidence that clonidine, an antihypertensive drug that affects the adrenergic nervous system, may not interfere with normal growth and maturation in adolescent males.

Adolescent