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Biomedical subjects

K Omae

Publications and source records attributed to K Omae.

61 records · Page 4Linked to original sources

Cross-sectional study of pulmonary function in cadmium alloy workers.

Two groups of cadmium workers (7 and 9 men) and a group of reference workers (122 men) were studied for the purpose of determining the pulmonary effects of cadmium. Indices of pulmonary function, based on the forced expiratory flow volume curve and respiratory impedance, were measured for all the groups, and indicators of cadmium exposure and effects on renal tubular reabsorption functions were also measured in the two groups of cadmium workers. The mean blood and urinary levels of cadmium were 2.08 microgram/100 ml (185.06 nmol/l) and 32.6 microgram/l (290.04 nmol/l), respectively, and the level of inhalation exposure was estimated at about 1 mg/m3 as the 8-h average concentration for about 5 a in the high exposure group. The percentage of the predicted function values of the highly exposed workers was significantly deteriorated for forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1.0), peak expiratory flow, maximum expiratory flow at 75, 50, and 25% of the FVC, percentage of FEV1.0 to FVC, and respiratory impedance, whereas those of the slightly exposed workers were reduced only for FVC and FEV1.0. A paired comparison between the highly exposed workers and matched referents disclosed the same results. It was concluded that chronic obstructive pulmonary changes had been induced by cadmium in Japanese workers without a history of acute or subacute cadmium pneumonitis.

Adult↗

[A personal diffusion sampler for evaluating time weighted exposure to gaseous hydrogen sulfide (author's transl)].

A simple badge type diffusion tube, 35 mm photo film plastic case, was used for evaluating time-weighted exposure to H2S using reagent impregnated filters (Whatman No. 1). The black shade of the reagent filter, 10% Pb(OAc)2 and 2% AgNO3 under the concentration of H2S below 20 ppm for 2 to 4 hours agreed inversely to the diffusion length of the tube, and lineally well correlated with dose-time unit (C X T) and the theoretical value of diffusion. The device was proved to be capable of being used in realistic working conditions provided that there is no extreme fluctuations of H2S.

Diffusion↗