Search PubMed⌕ Search

Biomedical subjects

K Ojima

Publications and source records attributed to K Ojima.

At least 91 records · Page 5Linked to original sources
PubMed1986

Recurrent paroxysmal hypotension and bradycardia in a patient with pharynx tumor metastasis to the cervical lymph nodes.

In a 64-year-old male, recurrent syncope, hypotension and bradycardia developed repeatedly. The systolic blood pressure fell and could not be measured by auscultation method and the heart rate decreased to under 20 bpm. He recovered from unconsciousness in several minutes. No precipitating cause was apparent for such episodes. Physical examination revealed swollen lymph nodes in the upper cervical regions. Carotid sinus massage caused a fall of systolic blood pressure by 40 mmHg and the P-P interval lengthened to 1.96 sec. The otolaryngeal examination showed neoplasma in the pharynx. He received irradiation therapy on the primary lesion and the bilateral metastatic lesions. After irradiation (4,000 rad), the paroxysmal hypotension and bradycardia disappeared concomitantly with the reduction in size of the metastatic tumor. Hypersensitivity to carotid sinus massage, however, remained unchanged. In this case, the metastatic tumor around the carotid sinus seemed to be related to the syncope and the hemodynamic collapse.

Bradycardia↗
PubMed1983

[Indium-111-oxine labeled platelet scintigraphy for detection of intracardiac and intravascular thrombi].

This study was designed to evaluate the efficacy of scintigraphy by using 111In-oxine labeled platelets for the detection of either intracardiac or intravascular thrombi. Fourteen cases of thrombi diagnosed or suspected on the basis of either angiography or two-dimensional echography were examined. They included four cases of left ventricular thrombi, three of left atrial thrombi, four of vascular thrombi and three of inflammatory disease. Platelet samples from the patients were labeled by 111In-oxine according to the method originated by Yui et al. The labeling efficiency was 72.4 +/- 9.8%. The platelets retained good function except for collagen aggregability. Hot areas of high quality in the scintigram were demonstrated in six cases including two with left ventricular thrombi, two with left atrial thrombi and two with vascular thrombi. These areas accorded well with the findings of angiography, echography or surgery. The removed thrombi had a layer of aggregated platelets on the surface. Platelet survival was shortened in a case of prosthetic valve endocarditis without a hot area, and was normal in four out of five cases including two with a hot area. It is concluded that this method is potentially predictive in detecting thrombi.

Adult↗
PubMedDate not supplied

Effects of postnatal exposure to cocaine on the development of the rat corpus callosum.

We investigated the effects of cocaine on the development of the corpus callosum in rats. From postnatal days 1 (P1) to 10 (birth = P0), cocaine (10 mg/kg) was subcutaneously injected in the pups, and saline, at the same volume, was administered to control pups. The animals were sacrificed at 110 days of age and a midsagittal section of the callosum was obtained. Morphometric measurement of the corpus callosum was performed in this section. In the control group, but not in the cocaine group, males had larger callosa than females. The cocaine treatment significantly decreased the total callosal area in male rats. These findings indicate that early postnatal cocaine abolishes the sexual differentiation of the corpus callosum.

Analysis of Variance↗
PubMedDate not supplied

[Homicide by strangulation with a lasso sling].

A 50-year-old physically handicapped man was found dead on his wheelchair in a short passage on the ground floor of a high-rise housing development. The lattice doors at the both ends of the passage were closed and the wheelchair with the body was found at the door to an adjoining indoor parking place for bicycles. A noose of a vinyl plastic cord was found wound around the neck; the other end of the cord was tied through the lattice door to a handrail on the wall of the parking place. The wheelchair was stopped sideways; its chair back was in contact with a doorpost. The body which was slipped from the seat of the wheelchair was incompletely suspended by the noose. The cause of death primarily was diagnosed as hanging. The police suspected murder and arrested a 21-year-old male assailant. According to his confession, the assailant pushed the wheelchair through the lattice door in the passage, stopped it at the door and braked it. Immediately thereafter he returned to the parking place and locked the lattice door behind him. After having made a kind of lasso using a cord taken off from a bicycle which has been sitting there, he reached out his hands through the lattice door and lassoed the man on the wheelchair from behind. Finally, he tied another end of the lasso to the handrail. It was considered that the body of the victim was slipped down in the stage of convulsion and incompletely suspended by the noose.

Asphyxia↗