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Biomedical subjects

K Numata

Publications and source records attributed to K Numata.

At least 163 records · Page 9Linked to original sources
PubMed1977

Tallysomycin, a new antitumor antibiotic complex related to bleomycin. II. Structure determination of tallysomycins A and B.

The structures of tallysomycins A and B, two major components of a new antitumor antibiotic complex, have been determined. They are glycopeptide antibiotics structurally related to bleomycin: four amino acid moieties and a disaccharide fragment which are the constituents of bleomycin molecule are also present in the tallysomycins. Tallysomycins A and B contain two new amino acids and a unique amino sugar, 4-amino-4,6-dideoxy-L-talose, which have not been hitherto found in the phleomycin-bleomycin group of antibiotics. In addition tallysomycin A has an additional amino acid, L-beta-lysine, and thus a longer peptide chain than bleomycin or tallysomycin B. Tallysomycins A and B have the same terminal amine moiety, spermidine.

Amino Acids↗
PubMed1976

Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. III. Structure determination.

The structures of sorbistins A1, A2, B, C and D have been determined including stereo-chemistry. Sorbistins A1, A2 and B are composed of a 4-acyl-amino-4-deoxy-D-glucose and 1,4-diamino-1,4-dideoxy-D-sorbitol, the latter compound being hitherto undescribed in literature. Sorbistins C and D have the same aglycone of 1,4-diamino-1,4-dideoxy-D-sorbitol, which is linked with D-glucose and 4-amino-4-deoxy-D-glucose, respectively, through a glycosidic bond.

Aminoglycosides↗
PubMed1969

[Local anesthesia].

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Anesthesia, Local↗
PubMed1969

[Pain clinic].

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Neuralgia↗