Isolation of a serogroup 29E meningococcal strain carrying Group-C siaD capsular gene.
Explore the source record for details and available documents.
Humans↗
Biomedical subjects
K Neil
Publications and source records attributed to K Neil.
An interview with Kate Neil: nutritional therapy explained. Interview by Denise Rankin-Box.
Kate Neil is a Visiting Lecturer at the University of Westminster for their BSc Health Sciences: Nutritional Therapy degree course. Kate was part of the team that established this course 2 years ago, which is the first of its kind in this country and supervised their clinical training programme. Previously, Kate was the Director of Education Studies and Principal of the Institute for Optimum Nutrition in London. She directs her own company NS3UK which offers nutrition services to health care professionals (including a 3-year nutrition course in Dorking), industry and the public. Kate frequently contributes to professional and public journals and is Editor of the professional journal The Nutrition Practitioner. She is also author of Balancing Hormones Naturally. She practises from Harley Street and from NS3UK in Berkshire. She can be contacted at NS3 UK. Tel.: 01344 360033; E-mail: kate@ns3.co.uk and www.ns3.co.uk. Kate is currently studying for an MSc in Nutritional Medicine at Surrey University.
Attitude to Health↗
Measurement of physical activity among black and white obese women.
Several recent self-reported surveys have suggested that African-American women may engage in less leisure-time physical activity (PA) than whites. Objective measurements of PA have not been performed, however. Therefore, the purpose of this study was to compare the components of energy expenditure, including PA, between black and white obese women. Using the doubly labeled water method, total daily energy expenditure (TDEE), basal metabolic rate (BMR), thermic effect of a meal (TEM), and PA were measured in 14 black and 15 white moderately obese women over 2 weeks. No statistically significant differences were seen between the 2 groups in BMR, TEM or TDEE. Mean PA was significantly (p = 0.05) lower among black women compared to whites when expressed as MJ. d-1 (3.49 vs. 4.30) or kJ.kg-1.d-1 (37.6 vs. 47.7). Our study supports the survey differences seen in PA among black and white women.
Adult↗
The mother-child relationship in the HIV-1 positive family.
Qualitative data (N = 80) from a larger study of HIV-1 positive mothers have revealed mother-child relationships, that is, a strong attachment along with a bond of secrecy. The relationship is described as a strong attachment along with a bond of secrecy. Children are perceived by the mothers as sources of support as well as sources of stress in the relationship. We conclude that practice and policy decisions concerning HIV-1 positive mothers should include emphasis on maintaining the health of the mother-child dyad, providing respite to mothers and providing support for future planning.
Acquired Immunodeficiency Syndrome↗
Phase behaviour of amphotericin B multilamellar vesicles.
Because side effect profiles and key physical properties of liposomal amphotericin B reflect the molecular nature of the hydrated preparations, effort has been directed toward understanding this nature. We describe here an examination by differential scanning calorimetry in the region of the main transition of the phase behaviour of amphotericin B multilamellar liposomes used investigationally for patient treatment. Liposomes were composed of 7:3 dimyristoylphosphatidylcholine/dimyristoylphosphatidylglycerol (7:3 DMPC/DMPG) containing up to 33 mol% drug. Preparations in which pure DMPC or pure 1-oleoyl-2-stearoylphosphatidylcholine (OSPC) was substituted for 7:3 DMPC/DMPG were subjected to the same measurements for comparison. The DSC-derived partial phase diagrams were similar to those previously recorded using EPR spectroscopy for unsonicated liposomes of 7:3 DMPC/DMPG containing amphotericin B, and for mixtures with different pure saturated and unsaturated phosphatidylcholines (Grant, C.W.M., et al. (1989) Biochim. Biophys. Acta 984, 11-20). Fluidization onset temperatures for liposome host matrices were relatively unaffected by drug compared to the temperatures of completion. This effect was particularly marked for the unsaturated phospholipid matrix. Partial phase diagrams were interpreted as demonstrating that amphotericin B has a tendency to separate into a rigid phase within the membrane. This is consistent with molecular modelling considerations which suggest that amphotericin B may exist as oligomers in a phospholipid matrix. Drug-induced alterations of DSC melting profiles for the phospholipid bilayers studied were less extensive than those reported for partially sonicated preparations of 7:3 DMPC/DMPG (Janoff, A.S., et al. (1989) Proc. Natl. Acad. Sci. USA 85, 6122-6126). Melting profiles obtained did not change upon further sample incubation, suggesting that the hydrated preparation represented a thermodynamically stable form.
Amphotericin B↗