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Biomedical subjects

K N Haque

Publications and source records attributed to K N Haque.

29 records · Page 2Linked to original sources

Isolated asternia: an independent entity.

Six cases of isolated asternia are described, their case histories and progress are reviewed. The relevant literature is reviewed and suggestions made towards etiology.

Female↗

Feeding pattern of children under two years of age in Riyadh, Saudi Arabia.

Mothers or other close relatives of children who were in hospital in Riyadh, were asked about their feeding practices. Sixty-four per cent of mothers of newborn babies had attended antenatal clinics, but only 10% had received any instructions on feeding. Of the hospitalized children only 27% were receiving breast milk alone by one month of age. However, of the 28% of mothers who had some education, 84% were breast feeding at three months of age. In Riyadh 36 brands of artificial milk feeds are available, and by three months of age, the average baby had been on six varieties of milk. Less than 14% of mothers intending to bottle feed could read the instructions, and of those who believed they knew how, only 18% made up the formula correctly. Educational opportunities need to be exploited and easy availability of artificial milk curbed.

Bottle Feeding↗

Is it necessary to regraduate milk after acute gastroenteritis in children?

To assess the best possible method of reintroducing milk in children suffering from acute gastroenteritis, 150 children (76 males and 74 females) admitted with acute gastroenteritis were allocated to one of three regimens: a. clear fluids initially, followed by increasing strengths of milk, in quarter strength steps; b. clear fluids initially and then reintroducing full strength milk; c. regimen of continuing full strength milk. There was no difference between the three groups in the outcome or in the length of stay in the hospital, but those who were continued on full strength milk gained more weight. The weight gain did not attain statistical significance; it is our impression on clinical grounds that this weight gain may be important in the malnourished infant who is more prone to enteritis.

Animals↗

A simple high calorie high protein feed for low birth weight infants in developing countries.

A simple high calorie high protein feed was devised by the addition of Caloreen and egg white to milk feeds for use in low birth weight infants (low birth weight--LBW). The growth rate was studied in 100 LBW infants. A weight gain of 203 g per week was obtained as compared to 110 g in the control group; growth was 8.6 mm in the study group as compared to 6.4 mm in the control group; the occipitofrontal circumference (OFC) was 0.67 mm in the study group and 0.38 mm in the control group. All differences were statistically significant.

Developing Countries↗

Dexamethasone in the treatment of hypernatraemic dehydration.

Ninety infants with severe hypernatraemic dehydration (plasma sodium greater than 150 mmol/l) were studied. Most had had a convulsion before admission. They were allocated to two treatment groups. Both groups received intravenous plasma followed by slow intravenous rehydration and correction of acidosis. In addition, one group received intramuscular phenobarbitone, the other group received dexamethasone 0.3 mg by intramuscular injection every 6 hours for 48 hours. Fewer infants receiving dexamethasone had convulsions during treatment (18% compared with 52%), and fewer (18%) of them died than in the group who did not receive dexamethasone (40%). Dexamethasone may have a role in the management of hypernatraemic dehydration in infants.

Blood Glucose↗

Immunotherapy in perinatal infection.

Though intravenous immunoglobulin (IVIG) have been shown to be beneficial in the treatment of some perinatal viral infections like varicella and possibly cytomegalovirus. The main thrust of interest has been directed towards the prevention and treatment of perinatal bacterial infections. This paper reviews literature published thus far (October 1991) on the use of IVIG in perinatal sepsis.

Bacterial Infections↗

Intravenous immunoglobulin for prevention of sepsis in preterm and low birth weight infants.

The effect of an intravenous polyvalent immunoglobulin preparation given prophylactically to prevent neonatal sepsis was tested in preterm and low birth weight infants. Infants matched for gestational age, sex and birth weight (+/- 250 g) were randomly allocated into 3 groups of 50 each, one group (Group C) being used as control. Group A received Intraglobulin (Biotest Pharma, West Germany), 120 mg/kg intravenously, within 2 to 4 hours of delivery; Group B received the same on days 1 and 8. The control group received no immunoglobulin. The frequency of infection and serum immunoglobulin concentrations were determined in each group. Infection rate in the control group was 16% (8 of 50) while in each of the treated groups it was 4% (2 of 50) (P less than 0.005). The immunoglobulin concentrations achieved in the treated group were significantly higher than the control group. No adverse effect of the therapy was noted during the study and at a 6-month follow-up. It is suggested that in nurseries where the infection rate is high, prophylactic intravenous polyvalent immunoglobulin therapy for the preterm and low birth weight infants may provide protection from infection.

Bacterial Infections↗