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Biomedical subjects

K N An

Publications and source records attributed to K N An.

At least 307 records · Page 17Linked to original sources

An in vitro biomechanical study of a hinged external fixator applied to an unstable elbow.

Details of the mechanical properties of hinged external fixators are essential to use the fixator properly in the clinical setting. A hinged external fixator (Dynamic Joint Distractor 2) was attached to the lateral side of 7 cadaveric elbows. Cantilever lateral bending tests were performed at 3 flexion angles in varus and valgus directions. Varied states of joint contact and axial loading were studied. Stiffness of the construct was calculated with uniaxial loading. Stiffness decreased with increased elbow flexion. Gap creation made the system less stiff. Axial loading made the system stiffer, especially in valgus testing. Stiffness in varus was approximately 4 times that in valgus. Lateral fixator application with half pins is most effective for protecting against varus-producing forces. When using the external fixator for unstable elbows, attention should be paid to the status of the articular surfaces and the integrity of the ligaments, and this should also be noted for elbow position during rehabilitation.

Aged↗

Axial loading induces rotation of the proximal carpal row bones around unique screw-displacement axes.

The changes in carpal bone alignment secondary to the application of an axial compressive load through the major wrist motor tendons while the wrist is kept in neutral position (isometric loading) have been investigated on 13 fresh cadaver specimens using a biplanar radiographic method of kinematic analysis. The scaphoid, lunate and triquetrum rotate an average of 5.1, 4.2, and 3.8 degrees, respectively, around different screw displacement axes, all implying flexion, radial deviation and supination. Based on these findings, a new interpretation of the mechanism by which the wrist remains stable under physiologic loads is provided.

Adult↗

Feasibility of using a magnetic tracking device for measuring carpal kinematics.

While several different methods have been used to measure carpal kinematics, biplanar radiography is generally considered to be the most accurate and popular one. However, biplanar radiography is tedious and so only pseudo-dynamic kinematics can be measured. Recently, magnetic tracking system has been developed for the measurement of joint kinematics which is versatile and easy to use and so the possibility of measuring motions dynamically. In this study, the capability of a magnetic tracking device to accurately measure carpal kinematics was investigated by comparing it with biplanar radiography. The kinematics of the third metacarpal, scaphoid, and lunate in five fresh cadaveric specimens were measured using both methods as the wrists were placed in eight positions. The finite screw rotation of each bone with respect to the distal radius during selecting the seven wrist motions was calculated for both measuring techniques and compared. In general, the kinematics for all three bones measured by using either magnetic tracking device or biplanar radiography was identical and showed no statistical difference. The averaged differences ranged from 0.0 to 2.0 degrees. These differences were due to the potential effect of the weight of the sensors and the interference of the attaching rod to the surrounding tissue. It is concluded that the application of the magnetic tracking device to carpal kinematics is warranted, if proper technical procedures as suggested are followed.

Aged↗

Functional comparison of pronation and supination strengths.

Studies have shown that functional activities involving pronation and supination, such as turning a doorknob or a screwdriver, involve wrist positions of extension and/or ulnar deviation. Previous studies of isometric forearm pronation and supination strength have utilized a neutral wrist position, resulting in a possible underestimation of true functional strength. Twenty healthy subjects between the ages of 24 and 45 years were assessed for isometric pronation and supination strength using cylinder, screwdriver, and doorknob handle adaptations. Maximal strength in both pronation and supination was observed with the use of the doorknob handle. Although pronation strength was exceeded by supination strength within all three handle adaptations, the difference was statistically significant for the screwdriver and doorknob handles. The results suggest that in clinical and research-oriented testing of maximal forearm rotation strength, further consideration must be given to the terminal grip device and positioning of the wrist.

Adult↗

Biomechanical analysis of tension band fixation for olecranon fracture treatment.

This study assessed the strength of various tension band fixation methods with wire and cable applied to simulated olecranon fractures to compare stability and potential failure or complications between the two. Transverse olecranon fractures were simulated by osteotomy. The fracture was anatomically reduced, and various tension band fixation techniques were applied with monofilament wire or multifilament cable. With a material testing machine load displacement curves were obtained and statistical relevance determined by analysis of variance. Two loading modes were tested: loading on the posterior surface of olecranon to simulate triceps pull and loading on the anterior olecranon tip to recreate a potential compressive loading on the fragment during the resistive flexion. All fixation methods were more resistant to posterior loading than to an anterior load. Individual comparative analysis for various loading conditions concluded that tension band fixation is more resilient to tensile forces exerted by the triceps than compressive forces on the anterior olecranon tip. Neither wire passage anterior to the K-wires nor the multifilament cable provided statistically significant increased stability.

Biomechanical Phenomena↗

Influence of rotator cuff tearing on glenohumeral stability.

This study hypothesizes that full-thickness tearing of the rotator cuff can lead to joint instability and that the degree of instability depends on the size and location of the tear. Twelve cadaveric shoulder specimens were divided into two groups: group 1 had a circular tear centered at the critical area, and group 2 had a circular tear centered at the rotator interval. Each group was tested at 2.5 cm and 5 cm tear sizes. Unloaded, and with the arm in 90 degrees flexion and full internal rotation, the humeral head shifted posteriorly. With loading, a large and more anteriorly located defect had the most influence on stability. The tear size had the greatest effect on stability in the inferior direction for group 1 and on the anterior direction for group 2. The tear location had the most significant effect on stability in the inferior and anterior directions for the smaller tear and on the anterior direction for a larger tear.

Aged↗

Shoulder muscle moment arms during horizontal flexion and elevation.

The instantaneous muscle moment arms of 10 shoulder muscles including the three portions of the deltoid and the rotator cuff and scapulohumeral muscle groups during four specified glenohumeral motions were calculated. Moment arm values were derived from a plot of tendon excursion versus glenohumeral joint rotation angle during horizontal flexion along the 90 degrees elevation plane and elevation in the sagittal, scapular, and coronal planes. The deltoid had the largest moment arm in elevation. The anterior deltoid has a larger moment arm in the anterior planes, whereas the midportion is greater in the scapular and coronal planes. The muscles with the largest depressor (adductor) moment arms are the pectoralis major, latissimus dorsi, and teres major. Contrary to the findings of other investigators, the supraspinatus and infraspinatus have a smaller potential elevation torque in the scapular plane than has been previously reported. Furthermore the subscapularis may potentially be a more important elevator in the scapular plane than either the supraspinatus or infraspinatus, especially in the latter phases of motion. The pectoralis major has the largest horizontal flexion moment arm with the humerus elevated 90 degrees, whereas the posterior deltoid and infraspinatus have the largest horizontal extension moment arms in this plane.

Adult↗

Reduction of triceps muscle force after shortening of the distal humerus: a computational model.

Bone deficiency resulting in shortening of the distal humerus may occur after fractures, treatment of nonunions, or revision of total elbow arthroplasty. A biomechanical model of the triceps muscle and tendon was used to investigate the effect of distal humeral shortening on triceps force production. The analysis indicated that shortening of the distal humerus primarily influences the media head of the triceps, which contributes most to elbow extension strength in extended elbow positions. In a posture of 30 degrees elbow flexion, shortening the distal humerus by 1, 2, and 3 cm reduced the extension strength by 17%, 40%, and 63%, respectively. At 90 degrees of flexion, strength was reduced by 11%, 15%, and 21%, respectively. This result suggests that shortening the humerus by 1 cm may be well tolerated, but shortening by 2 or more cm may cause a significant reduction in triceps force. This would be particularly important in patients requiring terminal extension strength for weight bearing.

Arm↗

Mechanical environment associated with rotator cuff tears.

A simplified 2-dimensional finite element model was used to investigate the stress environment in the supraspinatus tendon. The extrafibrillar matrix and collagen fiber were modeled with fiber-reinforced composite elements. The stress was evaluated at humeroscapular elevation angles of 0 degree, 30 degrees, and 60 degrees. Two acromion conditions were simulated. In the first set of conditions there was no subacromial impingement. In the second set there was subacromial impingement of the bursal side. Impingement was simulated by producing a 1-mm indentation on the bursal surface, an indentation similar to the type of impingement associated with deltoid contraction. The results demonstrated that subacromial impingement generates high stress concentrations in and around the critical zone. Such high stress could initiate a tear; tears that result from stress point to an extrinsic mechanism. However, we found that high stress and potential tears caused by impingement may occur on the bursal side, the articular side, or within the tendon. This result is unaccounted for by traditional mechanical models in which only bursal-sided partial tears are initiated by subacromial impingement.

Aged↗

Stress analyses of glenoid components in total shoulder arthroplasty.

Finite element analysis was used to characterize the local stresses at the bone-implant interface of 2 different types of glenoid components presently used in unconstrained total shoulder arthroplasty. A series of 2-dimensional finite-element meshes was developed to model the glenoid in 2 mutually perpendicular planes with and without implanted components. One of the implants modeled was a cemented all-polyethylene component, and the second was an uncemented metal-backed component. A variety of parameters were studied including the resultant loading direction (concentric versus eccentric), keel geometry, subchondral bone integrity, and cement mantle size. Results of the analyses show that the cemented all-polyethylene design demonstrated an overall stress pattern that was closer to that of the intact glenoid. When the effects of concentric and eccentric loading conditions were compared, the overall stress magnitudes in the subchondral bone were found to be much lower with the uncemented metal-backed component than with its cemented all-polyethylene counterpart. This finding suggests that some degree of stress shielding may be associated with the metal-backed component. In addition, under both the concentric and eccentric loading conditions, extremely high stress regions were found within the polyethylene near the polyethylene-metal interface of the uncemented metal-backed component.

Arthroplasty, Replacement↗

Role of collateral ligaments in the GSB-linked total elbow prosthesis.

The GSB III elbow prosthesis is a loose-hinged type of elbow implant. The introduction of such hinged elbow arthroplasty expanded the indications for elbow replacement to patients with more deficient bone and ligaments. The purpose of this study was to compare the kinematics and stability of the GSB III elbow prosthesis with that of the normal elbow and to investigate the role of the collateral ligaments in the kinematics and the stability of the GSB III total elbow prosthesis in an in vitro model. The results could show a semiconstrained kinematic pattern of the GSB III implant. The mean laxity for varus/valgus stress of the implant without collateral ligament support was significantly greater for all flexion angles when compared with intact elbows (mean, 12.7 degrees versus 5.4 degrees ) and with elbows treated with a standard implantation technique (mean, 9.5 degrees ). The release of the collateral ligaments increased the already observed varus shift after standard implantation of a GSB III elbow prosthesis. The laxity measured without collateral ligaments during loaded movement reached the maximum varus/valgus laxity of the GSB III prosthesis of 12 degrees degrees. The study confirms the role of the collateral ligaments in stabilizing the GSB III elbow prosthesis. Missing collateral ligaments may overload the implant-cement-bone interface and may be one factor contributing to early aseptic loosening of this device.

Aged↗

Medial or lateral dislocation (snapping) of a portion of the distal triceps: a biomechanical, anatomic explanation.

Medial and lateral snapping (dislocation) of the distal triceps over the epicondyle during elbow flexion has been reported but is frequently misdiagnosed and is not well understood. In this study a mathematical model was designed to simulate the effect that bony abnormalities at the distal humerus and soft tissue variations of the distal triceps have on the line of pull of the triceps. The predictions were then tested on prefabricated and fabricated plastic elbow models, as well as 8 cadaveric elbows. When the bony alignment was altered, varus angulation had the greatest effect: 30 degrees varus malalignment of the distal humerus displaced the centroid of the triceps vector medially by approximately 2.0 cm. Valgus malalignment had a lesser effect: 30 degrees valgus displaced it laterally by 1.5 cm. Negligible effects on the triceps line of pull were seen with internal or external malrotation and with flexion or extension malalignment. Of the soft tissue alterations, displacement of the triceps insertion had a greater effect than movement of the triceps origin. The triceps vector was displaced by approximately 70% of the amount of translation of the triceps insertion. The relationship between the triceps line of pull and the bony alignment is represented by the triceps (T) angle. Our use of the T angle to understand snapping triceps is analogous to the use of the quadriceps (Q) angle for patellar subluxation/dislocation. Treatment should aim to restore normal triceps biomechanics with soft tissue or bony procedures.

Arm↗

A 2-D model of wheelchair propulsion.

PURPOSE: To illustrate the potential benefits of kinetic and kinematic models in the exploration of biomechanical studies as illustrated using a simple 2-D static optimization model of wheelchair propulsion. METHOD: A four-bar linkage analysis was used to determine sagittal plane motion through the range of wheelchair propulsion. Using anthropometric measures of wheelchair users, this analysis determined the angles of shoulder and elbow flexion/extension at a given point in the propulsion cycle. Maximal strength inputs for the model were collected from isokinetic measurements of shoulder and elbow moments. The torque inputs were given as functions of sagittal plane joint angles. Through selection of appropriate model performance criteria, optimization techniques determined shoulder and elbow torque contributions throughout the propulsion cycle. Variations in the model parameters of anterior-posterior (AP) seat position and handrim size went used to show potential of model to evaluate wheelchair configuration using the performance criteria of propulsive moment (Mo) and efficiency as defined by fractional effective force (FEF). RESULTS: The model was able to predict the magnitude and direction of force applied to the handrim from shoulder and elbow moments. These joint moments may be examined along with the generated wheelchair axle propulsion moment. While the model showed no significant changes in either Mo or FEF for AP seat changes, an increase in handrim size was shown to increase FEF. CONCLUSIONS: This model was able to simulate wheelchair propulsion and allow for performance analyses. The open nature of the model allowed for tweaking of the kinematic inputs to examine the sensitivity of such factors as seat position and handrim size in wheelchair propulsion. Strength inputs to the model may also be altered to study the potential effects of strength training or muscle weakness.

Biomechanical Phenomena↗

Validation of three-dimensional reconstructions of knee anatomy: CT vs MR imaging.

This is the first investigation to validate the accuracy of spatial measurements based on computer-generated three-dimensional (3D) reconstructions of CT and magnetic resonance (MR) scans. Standard 3D reconstructions of one fresh frozen cadaveric knee specimen with implanted stereotactic reference markers were created. These reconstructions were based on the data from CT and MR scans performed before and after the resection of extraosseous soft tissues. The distances between the stereotactic reference markers in the 3D reconstructions were compared with the same measurements of the specimen using a Bridgeport milling machine as a precision 3D digitizer. The accuracy of intermarker distance measurements averaged 99% for CT-based reconstructions compared with 97.5% for MR-based reconstructions. Planar slices at a predetermined level and orientation through the femoral condyles were created by sequential milling of the specimen and were compared with reconstructed oblique planar CT and MR slices at the same level and orientation. The accuracy of condylar dimensional measurements was 94% for CT and 93% for MR compared with measurements of the milled slices. Three-dimensional reconstructions based on CT and MR scan data were of equally high quality and were unaffected by the status of the soft tissues.

Computer Simulation↗

Articular and ligamentous contributions to the stability of the elbow joint.

This preliminary study of four elbow specimens investigates the relationship of articular geometry and ligamentous structures in providing stability to the elbow joint. A technique is presented that describes the constraining features of varus-valgus and distraction in extension and at 90 degree of elbow flexion. Valgus stability is equally divided among the medial collateral ligament, anterior capsule, and bony articulation in full extension; whereas, at 90 degrees of flexion the contribution of the anterior capsule is assumed by the medial collateral ligament which provides approximately 55% of the stabilizing contribution to valgus stress. Varus stress is noted to be resisted primarily by the anterior capsule (32%) and the joint articulation (55%) with only a small (14%) contribution from the radial collateral ligament. At 90 degrees of flexion, little change is noted in the contribution to the radial collateral ligament (9%), but the anterior capsule offers only 13%, with the remaining stability (75%) arising from the joint articulation. In extension, the soft tissue resistance to distraction is provided minimally by either the radial (5%) or the medial (5%) collateral ligaments, and thus primarily originates from the anterior capsule (85%). At 90 degrees of flexion, however, the capsule offers virtually no resistance to distraction (8%). The radial collateral ligament contributes 10% of the stability, while the medial collateral ligament accounts for 78% of the resistance to distraction in this position. Too few specimens have been studied to form any conclusions for direct clinical applications at this time. However, the technique provides a reliable tool with additional studies for different positions and loading conditions underway. These efforts should disclose useful information that might be applied to the management of chronic elbow instability, radial head or olecranon fracture, the design and implantation of elbow prostheses, or provide a rationale for other reconstructive procedures.

Biomechanical Phenomena↗

Stability of the loaded ankle. Relation between articular restraint and primary and secondary static restraints.

The stabilizing capacity of the ligaments and articular surface in the ankle was determined under defined physiologic loading conditions. The concept of primary and secondary constraints was adapted to the ankle. With physiologic loading, the articular surface accounted for 30% and 100% of stability in rotation and version, respectively. That the articular surface was the sole source of inversion and eversion stability under the prescribed physiologic loading conditions has not been previously reported. The demonstration that the articular surface resists inversion displacement in the loaded ankle supports the conclusion of previous studies that rotation, rather than inversion, may account for a type of clinically symptomatic ankle instability. Further, ankle instability may occur during loading and unloading but not once the ankle is fully loaded. The results of our study confirm the importance of the anterior talofibular and calcaneofibular ligaments and suggest an important role for the deltoid ligament.

Adult↗