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Biomedical subjects

K Motegi

Publications and source records attributed to K Motegi.

At least 19 recordsLinked to original sources
PubMed1991

The effect of a change in dietary habit upon maze learning ability in rats.

An experimental psychological study was undertaken to assess the effect of a change in dietary habit upon behavioural development, using as a laboratory animal male Wistar rats maintained on natural foods and a processed food. Forty male Wistar rats were weaned at 21 days of age and divided into two equal groups. Group 1 was fed natural food (pressed wheat, dried fish, peanuts, cabbage and soybeans) and group 2 was fed powdered food. At 68 days of age, the rats were tested in a T-maze. The results showed that Group 1 excelled with regard to T-maze learning.

Animals↗
PubMed1990

[Two cases of solid and cystic tumor of the pancreas (including one case of MRI)].

Solid and cystic tumor of pancreas is an uncommon neoplasm which is histologically low grade malignant but amenable to cure by surgical excision. It tends to occur in young women. US and CT depict a well circumscribed mass that can be solid, mixed solid and cystic and largely cystic. Their ratio depends on the degree of hemorrhage and necrosis. Angiography shows a mildly to moderately vascular mass which corresponds to solid parts. MRI is useful to detect the hemorrhage which is common in this tumor.

Adolescent↗
PubMed1990

Unilateral parotid swelling after general anaesthesia. A case report.

An extensive swelling in the left parotid region, extending to the buccal and cervical areas, developed in a 30-year-old man immediately after a partial nephrectomy which was performed under general anaesthesia. Radiological examination immediately after the onset revealed no abnormality, but a large swelling was detected by computed tomography in the left parotid region. Serum amylase was significantly elevated. The clinical signs had almost disappeared approximately 2 weeks after the onset, following intravenous infusion of antibiotics and transfusion. This parotid swelling was considered to be acute postoperative parotitis induced during induction of anaesthesia by luxation of the temporomandibular joint or by the positioning of the patient during operation.

Adult↗
PubMed1989

Reduction and fixation of jaw fractures using acrylic splints.

This paper proposes the criteria for application of acrylic splints in the treatment of various types of maxillofacial fractures. These were based mainly on the number of remaining teeth that are important for the restoration of occlusion. The acrylic splints studied consisted of intermaxillary, lingual and labiolingual types that hold a dental arch and a cap type that covers a dental arch. It was found that the intermaxillary type was best indicated for the loss of multiple teeth, the lingual type for the predicted intraversion of bone fragments and the labiolingual as well as cap types for the deciduous or mixed dentition. Clinical application based on the above standard, which was attempted in our 60 patients, produced successful results. In addition, the usefulness of these acrylic splints as an intraoral apparatus was discussed.

Acrylic Resins↗
PubMed1989

Congenital midline sinus of the upper lip. Report of a case.

An extremely rare case of congenital midline sinus of the upper lip in a 12-year-old girl is presented. The sinus had a pit-like orifice in the midline philtral area with a duct extending 4 mm posterosuperiorly. It was excised by extraoral elliptical incision. Histopathological examination disclosed that the duct was covered by a stratified squamous epithelium with sebaceous glands. Twelve cases of this rare disease have previously been reported.

Child↗
PubMed1989

Mandibular lesions in patients with adenomatosis coli.

Adenomatosis coli is a very interesting disease accompanied by a number of associated stigmata in the mandible. If left ignored, colonic lesions in patients with this disease proceed almost entirely to malignancy. Hence, detection of the stigmata is very important. The panoramic radiographs of 26 patients diagnosed as adenomatosis coli at the 2nd Department of Surgery, Hamamatsu University School of Medicine from 1978 to 1988 were compared with those of 264 controls. Osteomatous lesions were present in 62% of the patients with adenomatosis coli and 14% of the controls. Pantomographic comparison of the numbers and areas of the osteomatous lesions between the adenomatosis coli and control groups indicated that specific pathognomonic symptoms were demonstrated in panoramic radiographs of approximately 42% of the patients with adenomatosis coli.

Adolescent↗
PubMed1989

[Automated instruments for clinical laboratory--its past and future].

Since the invention of the Autoanalyzer (flow system) by Skeggs in 1953 and Swedish invention of the AGA-Autochemist (discrete system) remarkable developments have been made in the field of clinical laboratory examinations. The Autoanalyzer was improved, from mono-channel to multi-channel, using various methods besides colorimetry, and with the aid of computers, it is now being applied to hematology and immunochemistry as well as chemistry. Although the AGA-Autochemist was something like a chemical factory at the beginning, various instruments using discrete system have been produced according to the refinement of the basic mechanisms of AGA-Autochemist. It is now used in other fields and has contributed considerably to clinical laboratory examinations. This article reviews the development of these instruments at intervals of five years, as reported or reviewed at the scientific meetings of the Japan Society for Clinical Laboratory Automation, and articles of the Journal of the Society. The evaluation of merits and demerits of clinical automation is omitted due to limitation of space.

Autoanalysis↗
PubMed1988

Articular eminectomy for long-standing luxation of the mandible. Report of 2 cases.

2 cases of long-standing luxation of the mandible are presented. Both patients were successfully operated on by articular eminectomy according to Myrhaug's description, with the purpose of both reposition of the condyles and prevention of redislocation. The articular eminectomy increased the ease of reduction and was effective in preventing future dislocation of the temporomandibular joint.

Aged↗
PubMed1988

Cleavage lines of the oral mucosa in Japanese cadavers.

Cleavage lines were experimentally reproduced in the oral mucosa of Japanese cadavers. They were investigated macroscopically and histologically. The reproduced cleavage lines showed little directional variation by sex or age. From the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.

Aged↗
PubMed1987

Pre-auricular (tragus) skin incision in fracture of the malar arch.

The malar arch consists of both the temporal process of the malar bone and the zygomatic process of the temporal bone. So far, there have been various different surgical approaches to the fractured malar arch. This report deals with 16 cases of the facial bone fractures including the malar arch. The usefulness of a pre-auricular (tragus) skin incision elongated to the haired temporal region is presented.

Adolescent↗
PubMed1986

Complete median cleft of the upper lip and alveolus with holoprosencephaly.

A case of complete median cleft of the upper lip and alveolus with holoprosencephaly is presented. An 8-month-old girl was successfully treated by closure of the median upper lip. In addition, 9 patients who have undergone cheiloplasty of complete median cleft of the upper lip with holoprosencephaly reported in the Japanese literature, are reviewed.

Abnormalities, Multiple↗
PubMed1986

Skin incision parallel with skin cleavage lines for access to the fractured zygomatic arch.

In surgery of the fractured zygomatic arch the skin incision was placed parallel with the skin cleavage lines, directly over the zygomatic arch. The fracture site was exposed by blunt dissection of the subcutaneous tissue. Facial palsy may be predicted as a possible sequel to this incision. In fact, facial paresis occurred in 1/3 of the patients but it disappeared within 6 months. It appeared that the facial nerve was only damaged by stretching during the surgical procedure but was not severed by the incision. The postoperative scars presented no unsightly appearance, if the incision was placed completely parallel with the cleavage lines.

Adolescent↗
PubMed1986

Cleavage lines of the skin.

Detailed investigation on cleavage lines over the entire area of the body was undertaken in 3 each of male and female cadavers. The directions of cleavage lines showed sex and individual differences. Minute comparison of the diagrams obtained in this study with earlier diagrams revealed the presence of delicate differences in the directions of cleavage lines. Microscopical evaluation of cleavage lines showed that in the regions where cleavage lines were linearly arranged, collagen fibers were regularly arranged in a uniform direction, conforming to the direction of cleavage lines from the shallow reticular layer immediately below the papillary layers to the inner reticular layer where sebaceous and sweat glands existed and that in the regions where cleavage lines were ramified, collagen fibers in these layers lacked directional regularity. The morphology of cleavage lines were considered most influenced by collagen fibers in the epidermal reticular layers from their shallow layers immediately below the papillary layers to the layer where sebaceous and sweat glands existed.

Adult↗
PubMed1986

Pharmacokinetic study of deuterium-labelled coenzyme Q10 in man.

The pharmacokinetics of coenzyme Q10 (CoQ10) in man was studied by utilizing deuterium-labelled coenzyme Q10 (d5-CoQ10). The absence of an isotope effect in the disposition of d5-CoQ10 in man was confirmed from the plasma concentration time curves after simultaneous oral dosing of d5-CoQ10 and unlabelled CoQ10. After oral administration of 100 mg of d5-CoQ10 to 16 healthy male subjects, the mean plasma CoQ10 level attained a peak of 1.004 +/- 0.370 micrograms/ml at 6.5 +/- 1.5 h after administration, and the terminal elimination half-life was 33.19 +/- 5.32 h. In most of the subjects, plasma d5-CoQ10 showed a second peak at 24 h after dosing. This unusual plasma level curve was well described by a newly proposed compartment model based upon the assumption that absorbed CoQ10 is taken up by the liver and then transferred mainly to VLDL and redistributed from the liver to the systemic blood.

Administration, Oral↗