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Biomedical subjects

K Moszyński

Publications and source records attributed to K Moszyński.

18 recordsLinked to original sources
PubMed1976

Dynamics of the blood pressure changes in sodium nitroprusside induced controlled arterial hypotension in neurosurgery.

Dynamics of the arterial blood pressure changes under the influence of intravenous infusion of sodium nitroprusside (SN) were studied in 12 patients operated on for intracranial aneurysms. Adequate measures were undertaken to avoid blood pressure (BP) changes due to the anaesthetic procedure itself. It was found that the speed of BP lowering corresponded to the rate of infusion, and could easily reach 10 mm Hg/min. After stopping the infusion, the BP recovery rate averaged a mean speed of 8.5 mm Hg/min, varying from 3.8 to 12 mm Hg/min. High speeds of BP lowering and recovery achieved with the use of SN are the main advantages of this hypotensive agent in neurosurgical procedures.

Adult↗
PubMed1976

Dynamic changes in cerebrospinal fluid pressure during neurosurgical operations.

The effects of hyperventilation, osmotic and diuretic agents (urea, frusemide), thiopentone and succinylcholine chloride on the intracranial pressure were studied in neurosurgical patients with brain tumours. We have shown that hyperventilation together with osmotic and diuretic agents is very useful for reducing increased intracranial pressure.

Brain Neoplasms↗
PubMedDate not supplied

[Sodium nitroprusside in controlled arterial hypotension during neurosurgical operations].

A 0.02% solution of sodium nitroprusside was given in intravenous drip infusion for induction of controlled arterial hypotension during intracranial operations. The drug was given to 9 patients operated upon for aneurysms and 2 patients with intracranial meningiomas. It was observed that arterial blood pressure could be easily controlled in this way for the purposes of operation.

Adult↗
PubMedDate not supplied

Controlled arterial hypotension during neurosurgical operations.

Controlled arterial hypotension was applied in 62 hyperventilated patients during neurosurgical operations. Hypotension was obtained using trimetaphan (19 cases), trimetaphan and halothane (32 cases) and sodium nitroprusside (11 cases). It was found that the action of sodium nitroprusside was the quickest and lasted the shortest, which considerably facilitated the control of hypotension. Halothane permitted hypotension to be obtained rapidly but in certain cases it prolonged the hypotensive action of trimetaphan.

Adolescent↗
PubMedDate not supplied

[Comparison of results of polygraphic sleep studies and cerebrospinal fluid pressure records in patients following removal of supratentorial expanding lesions].

In 4 patients operated upon for supratentorial brain tumors the authors carried out on the 3rd day after the operation polygraphic recording of nocturnal sleep with simultaneous measurements of cerebrospinal fluid pressure in the ventricular system by the method of Lundberg. A comparison of polygraphic records of nocturnal sleep with parallel measurements of intraventricular pressure demonstrated that all REM phases were associated with a rise in intraventricular pressure, while during phases 3 and 4 of sleep (NREM) the intraventricular pressure was always lower. In the remaining sleep phases 1,2 NREM and during episodes of nocturnal awakening no unequivocal consistencies were found.

Adult↗
PubMedDate not supplied

[Cerebrospinal fluid pressure measurements in the ventricular system during and after surgery in patients with supratentorial brain tumors].

In the light of CSFP measurements by Lundberg's method in 46 patients the authors showed the role of hyperventilation in lowering of intracranial pressure. A considerable efficacy of dexamethasone was demonstrated as well, the use of this drug permitted to achieve stabilization of CSFP during and after the operation. The investigations showed a considerable effectiveness of such drugs as mannitol and furosemide in lowering of CSFP. Pancuronium was found to be superior to suxamethonium for administration during induction of anaesthesia because the former caused no CSFP rise. In polygraphic investigations of nocturnal sleep with parallel recording of CSFP a rise of CSFP was demonstrated during REM phase of sleep.

Anesthesia↗
PubMedDate not supplied

[Results of polygraphic nocturnal sleep recording in patients with supratentorial brain tumors prior to and following surgery].

The purpose of the study was to establish the influence exerted by a supratentorial brain tumour on the EEG correlates of sleep, and to compare the results before and after operation. Five patients were studied (aged 38 to 59 years) who were treated surgically for supratentorial expanding lesions: two cases of meningioma (in left parietal area), two cases of glioma (right parietal area and occipital area) and one case of intracerebral haematoma. The control group comprised 5 patients operated upon for lesions of the peripheral nerves of extremities. In the patients with supratentorial brain tumours and after their removal the following sleep parameters were unchanged: total sleep duration, number of awakening during sleep, latency time of the first REM phase and stage 3 NREM (deep and superficial sleep). The amount of REM sleep increased after tumour removal. REM-sleep density was selectively and permanently disturbed. In presence of tumour REM-sleep density was found in traces only, after tumour removal it increased but showed a permanent high-grade deficit in relation to controls.

Adult↗
PubMedDate not supplied

Hyperventilation in neurosurgery.

An outline of the nature and varieties of hyperventilation is presented together with a discussion on the role of artificial hyperventilation in the management of neurosurgical patients. Attention is called to the value of gasometric investigations in the ventricular cerebrospinal fluid for evaluation of disturbances in pH of the intracranial environment and possible effectiveness of hyperventilation. The results of our measurements of cerebrospinal fluid pressure are presented in 21 cases of supratentorial cerebral tumours in which controlled ventilation with hyperventilation was conducted. In 19 cases, the cerebrospinal fluid pressure fell by a mean of 44.3% with a simultaneous fall of PaCO2 by 29.3%. In the conclusions the authors stress the role of hyperventilation in the lowering of raised cerebrospinal fluid pressure and prevention of cerebral oedema.

Acid-Base Imbalance↗
PubMedDate not supplied

[Changes in cerebrospinal fluid pressure in patients with hydrocephalus of various intensities].

In 12 patients with hydrocephalus caused by posterior fossa tumours continuous measurements of intraventricular CSFP were done before and after implantation of ventriculoatrial valve and after tumour removal. A fall of the mean CSFP from 31.57 mm Hg to 15.32 mm Hg was observed after valve implantation, and a further fall of the mean CSFP to 10.55 mm Hg after removal of the tumour. After valve implantation pathological A and B waves disappeared. Absence of improvement after different stages of treatment indicated poor functioning of the valve, but it was observed also in patients with inoperable tumours.

Adult↗
PubMedDate not supplied

[Studies on the cerebrospinal fluid pressure changes in patients treated for hydrocephalus by the so-called ventricular filling test. Preliminary report].

The curves of cerebrospinal fluid pressure (CFP) in the lateral cerebral ventricle during the so called ventricular filling-up test are presented in 6 patients with high-pressure and medium-pressure hydrocephalus as compared with CFP curves obtained in 2 patients with low-pressure hydrocephalus. The method of filling-up test (infusion test) is described. In this method portions of normal saline 2 ml each are administered rapidly into a lateral ventricle every 30 seconds. The obtained results demonstrated a difference in the shape of the CFP curves in patients with low-pressure open hydrocephalus as compared with patients with closed hydrocephalus. This could help in qualifying patients with hydrocephalus for treatment with ventriculo-atrial shunt.

Cerebral Ventricles↗