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Biomedical subjects

K Miller

Publications and source records attributed to K Miller.

At least 685 records · Page 38Linked to original sources
PubMed1975

Metabolism and temperature regulation in young harbor seals Phoca vitulina richardi.

Metabolism and the ability to regulate core and peripheral temperatures under a variety of ambient conditions were studied in five unrestrained pups (less than 5 wk old) and four 3- to 5-mo-old harbor seals. Pups born with nonlanugo (adultlike) hair and little fat were able to swim in 5 degrees C water for several hours without becoming hypothermic. They were also found to tolerate 5 degrees C air temperature with the fur wet and exposed to a 35-knot wind. Basal metabolism in pups averaged 0.8 ml O2 g-1 h-1, which is 2.6 times the predicted value for an adult mammal of the same weight. Lower critical temperature in air was about 3 degrees C. Oxygen uptake in 3- to 5-mo-old seals under basal conditions was 0.5 ml g-1 h-1. Minimal thermal conductance values were .02 and .015 ml O2 g-1 h-1 degrees C-1 in pumps and 3- to 5-month-old seals, respectively. Appendages, and to a lesser extent the skin on the torso, cooled appreciably at lower air temperatures, and the flippers were kept just above freezing in subzero air. Tissue insulation provided by low peripheral temperatures and a high resting metabolic rate enable newborn and developing harbor seals to tolerate the low temperatures encountered in their natural environment.

Animals↗
PubMed1975

The immunology of asbestosis.

Forty-one employees with varying degrees of asbestosis have been tested for any alteration in the immunological profile. Of these, twenty-two employees showed evidence of pleural thickening and nineteen parenchymal asbestotic fibrosis. Those employees showing pleural thickening gave a strong reaction to different skin tests and a few of those with a parenchymal asbestotic fibrosis showed depressed cutaneous reactivity. Lymphocytotoxic antibodies were present in the sera of 60% of those with pleural thickening and 94% of those with parenchymal asbestosis. An immunological screening schedule is suggested for those employees who show pleural thickening.

Asbestosis↗
PubMed1972

Galactokinase: evidence for a new racial polymorphism.

Activities of galactokinase and galactose-1-phosphate uridyltransferase in red cells were assayed in a mixed racial population of 645 pregnant women. The distribution of individual transferase activities for black subjects was the same as that for whites. In contrast, the distributions of individual galactokinase activities differed significantly in blacks and whites, the mean for the black population being 30 percent lower than the mean for the white population. The same racial difference was found when red cell galactokinase activity was examined in males and in newborns. Because low-, intermediate-, and high-galactokinase activities appear to segregate within several black families, this observed difference suggests a new, racially determined enzyme polymorphism.

Adult↗