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Biomedical subjects

K Menzel

Publications and source records attributed to K Menzel.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Behavior of the oxygen half-saturation value and HbF content of blood of newborn infants during blood exchange transfusion].

An evaluation of the HbF-content and the oxygen-half-saturation value took place in 15 newborn infants before, during and after an exchange transfusion. The initial HbF content decreased to 25% after the exchange transfusion with ACF-blood. The p50-value did not increase, as expected, but decreased dependent on the volume of the exchanged blood, caused by a quick loss of 2.3.-DPG in the ACD-blood within the first two days of storage. A normalization could be demonstrated 24 hours after the transfusion.

Blood Volume↗
PubMed1989

[Sonography in the diagnosis of Hodgkin's disease in childhood and adolescence].

We are reporting about the results of the staging by ultrasound in 11 children with Hodgkin's disease. Sonography stands the test as a method that reliably predicts abdominal involvement in patients with Hodgkin lymphoma. Only in a few cases an indication for an additional computerized tomography is given. A demonstration of typical ultrasonic findings takes place.

Child↗
PubMed1989

[Comparison of O2-exposed premature infants with and without vitamin E substitution from the ophthalmologic viewpoint].

The present paper deals with the efficiency of vitamin E in the prevention of progress of ROP. 80 premature infants with oxygen therapy and vitamin E all from the year 1986 are compared with 80 premature infants with oxygen therapy without vitamin E from the years 1984 and 1985. The group with protection by vitamin E shows a smaller rate of the higher stages of ROP. The stages II-V could be prevented in the studied group. The two groups of infants are too inhomogenous for an exact statistical analysis because some other factors are meaningful.

Dose-Response Relationship, Drug↗
PubMed1989

[Treatment of post-hemorrhagic hydrocephalus in premature infants].

Our experiences in the course of illness of very low birth weight infants suffered from posthemorrhagic hydrocephalus are described. Clinical proceedings for performing of the hydrocephalus are explained, advantages and disadvantages of treatment by serial lumbal punctures, influences of drugs on the dilatation of the ventricles and the insertion of ventriculo-peritoneal shunts are discussed. The outcome was unfavourable in hydrocephalus following Grad III ore IV hemorrhage. Therefore the prevention of severe hydrocephalus must be the common sense of obstetricians and neonatologists.

Cerebral Hemorrhage↗
PubMed1989

[Immunologic findings in the newborn infant. I. Studies of cellular immunity].

Based on investigations of 133 healthy full-term newborns in the first 3 days of life parameters of cellular immunity are described. The lymphocyte count of 28.5 +/- 10.9% (mean +/- S.D.) or 4.45 +/- 1.99 Gpt/l respectively coincides with literature values. Estimation of T-lymphocytes (E-rosette method) yields a percentage of 67.5 +/- 10%, which is not different from adults, whereas the absolute number 2.99 +/- 1.42 Gpt/l is markedly higher. Measuring phytohemagglutinin induced lymphocyte transformation one often finds a high spontaneous activity in unstimulated controls. The transformation rate, then, is low. 14 of 129 samples had unstimulated control activities higher than with phytohemagglutinin so that stimulation indices could not be calculated. Fairly good lymphocyte transformation was found in more than a half of all newborns. There is no correlation between the absolute value of stimulation index and the phytohemagglutinin-concentration.

Female↗
PubMed1989

[Immunologic findings in the newborn infant. II. Studies of humoral immunity, reference values of immunologic studies in the newborn infant].

After dealing with cellular immune aspects in the first part of the paper the authors describe in the second part the state of humoral immunity in healthy full-term newborns aged one to three days. The number of complementreceptor lymphocytes was 17.0 +/- 8.9% or 0.75 +/- 0.51 (mean +/- S.D.) respectively, with the EAC-rosette method. The percentage value equalled that of adults but the absolute count is higher. Using the immunodiffusion method IgA was detectable in 4 out of 132 newborns only 8.86 +/- 2.52 g/l (mean +/- S.D.) was measured as an average IgG concentration. With regard to the IgM content the values often exceeded 0.30 g/l in newborns of mothers who had been suffering from pre-eclampsia. Their mean value of 0.35 +/- 0.21 g/l, too, was significantly higher than 0.13 +/- 0.08 in the resting infants. Raised IgM values frequently coincided with high spontaneous transformation activities in lymphocyte cultures. The possible causes are discussed. Complement C3-component was measured on average with 0.78 +/- 0.18 g/l and C4-component with 0.34 +/- 0.11 g/l. When calculating reference values for newborns the results of infants with maternal pre-eclampsia have been omitted.

Complement C3↗
PubMed1987

[Differential acetonemic vomiting diagnosis--recurrent Addison crises as an early sign of adrenoleukodystrophy].

After 5 years of cyclic vomiting an 8 year old boy was presented with coma and hyponatremia. ACTH and renin plasma concentrations were elevated, cortisol concentrations did not rise after ACTH-stimulation. Behavioural abnormalities including secondary enuresis and dysarthria drew attention to the possibility of an association of adrenal insufficiency with leucodystrophy. NMR tomography of the brain showed symmetrical demyelinated areas in the parieto-occipital regions. Very long chain fatty acids were elevated. The mother showed discrete neurological symptoms and elevated long chain fatty acids. Cyclic vomiting might suggest adrenoleukodystrophy.

Addison Disease↗