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Biomedical subjects

K Mathias

Publications and source records attributed to K Mathias.

At least 55 records · Page 3Linked to original sources

[Nonsurgical treatment of a massive macrohematuria following kidney biopsy].

In the treatment of massive hematuria after renal biopsy, selective percutaneous vaso-occlusion with detachable balloons is an effective alternative to urological surgery, as demonstrated in the case of a 39-year-old man. A review of the literature, which records success rate of more than 90% in nonmalignant renal hemorrhage, confirms the therapeutic value of the various parenchyma-sparing embolization techniques.

Adult↗

[Catheter treatment of arterial occlusive disease of supraaortic vessels].

Catheter dilatation can be applied in occlusive vascular disease affecting the proximal and distal subclavian, vertebral, and innominate arteries and common internal and external carotid arteries. The treatment of 102 patients is reported to demonstrate the efficacy of percutaneous transluminal angioplasty in this vascular region with a technical success rate of more than 90% and a patency rate of 75% after a follow-up of more than 3 years. The complication rate is low, transient ischemic attacks having occurred in only 2 of these cases.

Angioplasty, Balloon↗

[Gorham-Stout syndrome of the mandible].

A 16-year-old female complained of loosening of several teeth in the lower jaw. Radiography revealed bone resorption of the tooth sockets. The osteolytic process extended throughout the alveolar crest of the mandible and caused a complete loss of teeth within 2 years. Microscopic sections showed angiomatous tissue of Gorham-Stout-syndrome. Radiotherapy with 35 Gy controlled the mandibular osteolysis. Recurrent meningitis and osteolytic defects of the frontal skull base hint at an additional manifestation of the disease at this site.

Follow-Up Studies↗

[Radiological contribution to the treatment of primary and secondary liver tumors].

The prognosis of patients with primary and secondary liver tumors has been improved recently by more aggressive operative, chemotherapeutic and embolization treatments. In a personal series of 40 patients with liver metastases from colorectal cancer, regional intra-arterial chemotherapy was superior to systemic intravenous treatment, with a tumor remission rate of 66% in comparison to 48% of the cases. But the benefit of intra-arterial chemotherapy is still questionable considering the higher complication rate and the absence of prognostic data of the procedure.

Adult↗

[Effect of contrast media on glycoside-induced mesenteric ischemia].

Experiments in 12 dogs have shown that intra-arterial injection of hyperosmolar contrast into the superior mesenteric artery normally produces a 52% increase in blood flow lasting more than two minutes. Following digitalis-induced mesenteric ischaemia, vaso-dilatation is equally marked, but lasts two and a half times as long. In view of the prolonged vaso-dilator effect of hyperosmolar contrast, arterial spasm could be missed during angiography.

Angiography↗

Value of angiography, sonography, and CT in renal infarction.

The value of angiography, sonography, and computed tomography as diagnostic methods for renal infarction is discussed. In all cases the infarct could be demonstrated angiographically, but not by sonography. In the case of a former infarct, the involved area appeared as a tumour mass by sonography and enhanced CT-scan showed contrast enhancement of the mass.

Aged↗

The effect of contrast media on the aortic endothelium of rats.

The effect of diatrizoate, ioxitalamate, metrizamide, and ioxaglate on the aortic endothelium of the rat was investigated using transmission electron microscopy and DNA synthesis autoradiography. One milliliter of each contrast medium, containing 300 mg iodine per ml, was injected into the aorta. The types of lesions seen on electron microscopy and the rate of DNA synthesis seen on autoradiography established the degree of endothelial damage that had been produced. Of the four contrast agents tested, ioxaglate produced the least amount of cellular change.

Animals↗

[Catheter dilatation of arteries supplying the brain].

Stenoses of the extracranial cerebral arteries can be successfully treated with percutaneous transluminal dilatation (PTD). Early and late results of PTD are comparable to those of vascular surgery, but are not accompanied by its morbidity and mortality rates. In 32 patients with subclavian steal syndrome PTD showed a technical success rate of 88% and a clinical cure rate of 72%. The fibrodysplastic carotid artery stenosis is well suited for PTD. These lesions often extend to the skull base causing difficulties for surgical correction. First experiences with PTD of atherosclerotic carotid artery stenosis are promising, but the efficacy of this procedure must be confirmed by a greater number of treated patients. PTD of the vertebral and basilar arteries present new therapeutic possibilities in the management of vertebrobasilar insufficiency demanding further evaluation.

Adolescent↗

[Subclavian Steal syndrome-operation or dilation? (author's transl)].

Percutaneous transluminal angioplasty was performed in 15 patients with supra-aortic obstructions. One of two subclavian artery occlusions could not be recanalized. the intervention did ot improve the circulation disturbance in two patients. A favorable treatment effect was observed in 80% of the cases, a result not very different from operative corrections. No complications occurred. The risk of angioplasty of the carotid bifurcation is unknown and, therefore, vascular surgery will remain the preferable method of treating atherosclerotic lesions of this location. In our opinion, angioplasty should be considered when operative correction requires thoracotomy and when the operative risk is increased. This is especially valid in proximal subclavian artery stenosis with and without subclavian steal syndrome, as well as in stenosis at the origin of the vertebral artery.

Adolescent↗