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Biomedical subjects

K MacMillan

Publications and source records attributed to K MacMillan.

26 records · Page 2Linked to original sources
PubMedDate not supplied

Tunable dye laser neovessel ablation as an adjunct to the management of hypertrophic scarring in burned children: pilot trial to establish safety.

Hypertrophic scarring is a major source of morbidity in patients with burns. The physiologic characteristics are poorly understood, but increased neovascularity is typically seen in those wounds destined to become hypertrophic. We theorize that ablation of the developing neovasculature may favorably influence the development of the hypertrophic scar. The goal of this pilot trial was to establish the practicality and safety of tunable dye laser neovessel ablation at 585 nm. Ten sites of evolving hypertrophic scar in nine children were treated with a series of 450 msec 6.75 J/cm2 pulses at 585 nm. Although all children had the expected transient posttreatment purpura, no pain, ulceration, pruritus, or worsening of the lesions was seen. The technique appears safe and is worthy of continuing investigation. Investigations with higher fluences and multiple treatments are in progress.

Burns↗
PubMedDate not supplied

Tobacco use and ethnicity: the existing data gap.

Tobacco use contributes substantially to the burden of illness throughout the world. Significant efforts have been made to design health promotion programs for the prevention and cessation of tobacco use in North America. However, most of these programs have been planned and implemented on the basis of needs assessments conducted among the dominant cultural group. Evidence exists that lifestyle modification and tobacco cessation programs must be culturally relevant to ensure successful outcomes. A review of the literature from nursing, anthropological and epidemiological perspectives suggests that there is a paucity of data available on the largely culture-dependent values which influence the decision to use tobacco in those groups which comprise the Canadian multicultural mosaic. The interpretation of results from existing studies is limited by a number of recurrent methodological flaws. The implications of this review for future research and public health planning are discussed. The development of culturally appropriate programs directed at the prevention and cessation of tobacco use remains a significant challenge for health professionals.

Canada↗