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Biomedical subjects

K Maĭnkhard

Publications and source records attributed to K Maĭnkhard.

At least 19 recordsLinked to original sources

[Endometriosis in the surgical scar from cesarean section].

The frequency of endometriosis in and around the surgical scar from cesarean section is from 0.03%-0.04% to 0.8% in some reports. It is difficult to be diagnosed, in spite of the typical symptoms: aching swelling in the area of the surgical scar, which is influenced by the phases of menstruation. Sonography and fine-needle biopsy can be used, but it is usually diagnosed through the surgical treatment. Hystological diagnosis can also be a matter of some difficulty, as sometimes it is necessary to differentiate from adenocarcinoma, pseudomyxoma peritonei and metastatic carcinoma. The treatment is surgical. It is examined a case of endometriosis, which occurred in the surgical scar from a cesarean section about a year after the operation. The treatment is surgical by means of wide cutting-out of damaged musculus rectus abdominis and the surrounding tissues. After the operation a seroma is formed, which is healed with aspiration drainage and compressive bandage. Three years after operation a recurrence is not established.

Abdominal Muscles↗

[The etiology of infectious cervicitis in women].

Infectious cervicitis is a common disease in women of reproductive age. A prospective study was carried out including 70 women with clinical manifestations of cervicitis during gynecological and colposcopic examination. In 19 women (27%), Chlamydia trachomatis was demonstrated by direct immunofluorescence in cervical smears. Neisseria gonorrhoeae was isolated in 2 women and 1 had a concomitant infection with Neisseria gonorrhoeae and Chlamydia trachomatis. Mycoplasma hominis and Ureaplasma urealyticum were isolated in 7 patients and 4 had cytological smears consistent with Human Papilloma Virus infection. In the rest 47 patients no etiological agent was found. The results of the present study indicate that the most common etiological cause for infectious cervicitis can be Chlamydia trachomatis and an examination for this organism should me mandatory in women with infectious cervicitis for guiding the correct diagnosis and treatment.

Adolescent↗

[The correlation between the study data on the Papanicolaou cytological smear and the data on direct immunofluorescence for C. trachomatis].

A study was carried out to examine the relationship between the clinical data, the data from the Papanicolaou smear and the direct immunofluorescence for C. trachomatis in 70 women with infectious cervicitis. The prevalence of Chlamydial infection in the study population was 27%. The study showed that one third of the women in whom the Papanicolaou smear revealed inflammatory changes might be expected to be infected with C. trachomatis. The probability of not having infection when no inflammatory changes were observed in the Papanicolaou smear was 0.74--negative predictive value which means that more than two thirds of the women without inflammatory changes in cytology smear will not be infected with C. trachomatis.

Antigens, Bacterial↗

[Problems of diagnosis and treatment of cervicitis].

Infectious cervicitis is a common disease in women of reproductive age. The symptoms are not characteristic and they are often neglected by the patient and the physician. Cervicitis is a very important clinical entity, because the infection can ascend to the genital tract. The most common causes for the infectious cervicitis are Chlamydia trachomatic and Neisseria gonorrhoeae. A variety of methods for the precise diagnosis must be employed--gynecologic examination, colposcopy, pathomorphology and cytology and bacteriological examination as well. Therapeutic modalities must include coverage for both Chlamydia trachomatis and Neisseria gonorrhoeae. Bacteriological test of cure is mandatory.

Adolescent↗

[Cytological and histological parallels in atypical colposcopic findings].

The aim of the present study was to analyse the cytological and histological equivalents in 112 patients with atypical colposcopical findings. The results showed the follow distribution of the findings: for cytological examination in 66 of the patients-I gr. PAP, in 32-II gr. PAP, in 6 III-A gr. PAP, in 1-III-B gr. PAP, in 4-IV gr. PAP and in 3-V gr. PAP. The histological study of the obtained target biopsies established: 7 cases with normal epithelium, 82 with different findings of abnormal epithelium with or without nonspecific and specific inflammatory changes; 18 cases with dysplasia from I to III degrees, 2 cases with CIS and 3 with invasive cancer. The degree of correlation of the different findings, as well as the possible causes for hypo and hyperdiagnostic assessments are discussed.

Adult↗

[Pelvic actinomycosis].

Actinomycosis is an uncommon inflammatory disease of the female genital tract predominantly affecting the upper sections. Its appearance is in close connection with expended use of different IUDs. Its histological demonstration needs the detection of the specific sulphur granules. Because they often are rare it is recommended working of 8-12 paraffin blocks from suspected cases. The exact diagnosis is of high significance for preventing possible recivides after surgical intervention.

Abscess↗

[The diagnostic value of dilatation and curettage in endometrial carcinoma].

The diagnostic accuracy of endometrial curettage is studied in 75 patients treated for endometrial cancer with respect to: 1. Detection of endometrial cancer; 2. Histologic type and grade of the cancer; 3. Spread to the cervical canal. It is found that: 1. The diagnosis of cancer by D&C is correct in 84% of cases; 2. The diagnosis of adenosquamous cancer is made by D&C in 25%; 3. Evidence of spread to the cervical canal by D&C is found in 24 cases and confirm ed by surgery in 7 (29.2%) cases, giving a false positive rate of 70.8%. Negative finding in py with target biopsy is advisable in cases of: 1. Positive cervical finding in the D&C specimen; 2. Negative finding in D&C specimen amd persisting symptoms.

Aged↗

[Tumors in childhood and adolescence].

The trial present the results for the incidence and histology of tumours in patients below 18 years, examined at the State University Hospital Maĭchin Dom in Sofia for two consequent periods of 4 years each. An increase is registered in the incidence of neoplastic disease from 1.85% to 3.42%. There is no significant difference in hystological characteristics of the tumours when comparing I and II period: 85.7% versus 77.4% benign tumours (mucous cysts, dermoid ovarian cysts and polyps) and 14.3% versus 22.6% malignant tumours (ill differentiated teratomas, cystadenocarcinomas, dysgerminomas, ovarian embryocarcinomas and rhabdomyosarcomas). Accurate diagnostics requires detailed gynaecological examination, including a rectal one, vaginal probing, vaginal scopia, ultrasound, laparoscopy. Early discovery followed by surgery provides a possibility for adequate and definite treatment.

Adolescent↗

[Endometrial hyperplasia and carcinoma in situ].

Endometrial hyperplasias--both simple and adenomatous are presented, as well as the differences between them and the endometrial carcinoma. The concept of endometrial carcinoma in situ (ESIS) and the criteria for invasiveness by the malignancies of the uterine corpus are discussed. Illustrations for various cases with ESIS are provided and the clinical behaviour by ESIS is discussed.

Adenocarcinoma↗

[Massive ovarian edema--a case report].

A case with massive ovarian oedema, which is a rare pseudotumorous condition in young women, is described. The conceptions about the etiology and pathogenesis are considered as well as the morphological changes (with the corresponding clinical symptoms) which could be found in the affected ovary. Attention is drawn to the differential diagnostical difficulties and to the possibilities of semiconservative treatment of this rare clinicomorphological entity.

Adult↗