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Biomedical subjects

K M Ferguson

Publications and source records attributed to K M Ferguson.

40 records · Page 3Linked to original sources

Fructose and hormone levels in semen: their correlations with sperm counts and motility.

Levels of fructose, growth hormone (GH), prolactin (HPr), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and 5alpha-dihydrotestosterone (DHT) were determined in semen. The samples were obtained from patients attending an infertility clinic and separated into four groups according to the number of spermatozoa. Levels of HPr, LH, and FSH showed significant positive correlations with sperm counts. Significant differences in fructose and hormone levels were found between various groups. Expressed as concentrations of hormones or fructose per milliliter of semen, none of the hormones showed a significant negative correlation with sperm motility whereas fructose showed a significant negative correlation. Expressed as amounts per ejaculate of semen, only prolactin showed a significant positive correlation with sperm motility. The significance of these findings is discussed.

Cell Count↗

Hormonal assessment before and after vasectomy.

Animal experiments have suggested that vasectomy may disturb the endocrine function of the testis. To explore this possibility in man blood was obtained from 277 men who had undergone vasectomy up to six years earlier or who were about to undergo the operation. Mean plasma testosterone concentrations seemed to be slightly higher in those who had undergone vasectomy than in the preoperative group, although this difference was not statistically significant. There was no significant difference between these two groups in the concentrations of luteinising hormone, follicle-stimulating hormone, prolactin, or oestradiol.

Adult↗

Sexual precocity associated with a hypothalamic tumour. Effects of sex hormone therapy.

A case of sexual precocity of unusually early onset and associated with a hypothalamic tumour is described. The effects of ethinyl oestradiol and medroxyprogesterone acetate treatment have been monitored by plasma testosterone, FSH, and LH estimations. The results suggested a partial suppression of the tumour's influence, the mechanism of which is discussed.

17-Ketosteroids↗