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Biomedical subjects

K Leszczynski

Publications and source records attributed to K Leszczynski.

22 records · Page 2Linked to original sources

Sizes and sources of field placement error in routine irradiation for prostate cancer.

Discrepancies between prescribed and treated field edges have been measured from 76 film pairs taken on 29 patients being treated for prostate cancer. The distribution of field edge discrepancies is described by a standard deviation of 4.5 mm and has an average absolute value of 3.5 mm. The observed discrepancies are shown to be attributable to field position errors and hence, in principle, are easily rectifiable.

Carcinoma↗

Effects of Arctic ozone depletion and snow on UV exposure in Finland.

The increase in the UV exposure of the Finnish population associated with the combined effects of ozone depletion and snow reflection was studied with the aid of theoretical calculations based on Green's clear sky UV model. A simple formula was utilized to transform horizontal irradiances to vertical irradiances averaged over 360 degrees azimuth angle. The model was verified with spectral and broadband measurements. The difference between the theoretical and measured UV radiation falling to horizontal surfaces was in most cases less than +/- 10%, and the additional error to theoretical vertical irradiances was less than +/- 10%. The calculations show that the annual horizontal doses in Helsinki (60.2 degrees N, 25 degrees E) are about 35% higher than in Saariselkä (68.4 degrees N, 27.5 degrees E), but the difference is only 16% for vertical doses owing to the stronger contribution to vertical (facial) surfaces of the reflection of UV from snow. At Saariselkä, the maximum vertical irradiance at the end of April approaches the midsummer values. The ozone depletions up to 40% in February and March 1992 had no significant effect on the annual doses because the total ozone returned to normal before the UV increased to biologically significant levels.

Arctic Regions↗

Objective evaluation of fibrosis in human testicular biopsies by analysis based on optical diffractometry.

Bilateral testicular biopsies were obtained from 27 patients and submitted to two different treatments for each of them: firstly, a classical fixation and colouring, permitting the histopathological diagnosis and subjective appreciation of the degree of fibrosis; secondly, a new objective technique based on optical diffractometry: this method is based on the analysis of light intensity distribution in the diffraction pattern of an original image. Using two different methods of discriminant analysis, we observed some errors due to the subjective examination; in particular, several fibrosed samples had been judged as 'normal' by the histopathologist. Moreover, we showed the existence of some heterogeneity between different slides from the same original biopsy.

Biopsy↗

Video techniques for on-line portal imaging.

The application of on-line portal imaging techniques to the verification of treatment precision is reviewed. The design parameters for a video portal imaging system are described, and the optimization of image quality is discussed with particular emphasis on photon noise. On-line images are presented for a head phantom imaged on a 4 MV linac, and compared with a conventional portal film. The relative advantages of an on-line system are compared with conventional portal film analysis.

Humans↗