Skilled nursing program with a rehabilitation emphasis.
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Aged↗
Biomedical subjects
K Lamb
Publications and source records attributed to K Lamb.
The association of atopic diseases with endometriosis.
Comparisons of the incidence of health-related problems were conducted between women with demonstrable endometriosis (N = 88) and a control group (N = 88). Increased incidence of respondents' reports of allergic manifestations (p less than .005) were found. Directions for further research are suggested.
Candidiasis↗
Family trait analysis: a case-control study of 43 women with endometriosis and their best friends.
Analyses of lineage patterns show that for 43 women with endometriosis who reported that other family members have the disease, the vast majority of these familial cases involve the maternal lineage (79% to 93%). Of these women 34.9% of their mothers and 21.2% of their sisters were affected. With use of these rates, expected rates for first-degree relatives in a general population of women with endometriosis were determined. These rates were 6.2% and 3.8%, respectively; in combination, these rates yield an overall risk of 4.9% for first-degree relatives. Prior studies estimated this overall risk to be 6.9%; however, z scores determined that these rates do not differ statistically. Rates for second-degree maternal relatives are reported for grandmothers and aunts (0.4% compared to 3.1%, respectively), thus expanding results of former studies. In combination, an overall risk of 1.9% is estimated for second-degree relatives, as measured.
Adult↗
Tampon use in women with endometriosis.
This study examines the potential role of vaginal tampons in women with endometriosis. In light of the fact that some medical practitioners view an appliance worn internally as a form of medical device, and in light of the recent knowledge about tampons gained during the crisis surrounding Toxic Shock Syndrome, little published information about women's menstrual patterns and practices was found. The data used here were provided by 470 members of the Endometriosis Association. These respondents' medical, surgical, and fertility case histories are stored in the Association's Data Registry housed at the Medical College of Wisconsin. Cases in this study are white; the average age is 31 +/- 5.2 years and 82 percent report use of tampons routinely. In contrast, general rates of tampon use, derived historically from several published studies using control groups matched to cases of Toxic Shock Syndrome were used for comparison. Results showed that rates of tampon use for women with endometriosis were similar to rates reported for the general population, 75 to 83 percent. We did find that within this group of mature white women, initiation of tampon use varied by age. Supporting Irwin and Millstein's study of tampon use in adolescent girls, an analysis of variance showed these women initiated tampon use at progressively earlier ages (p less than 0.001).
Adolescent↗
The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia.
The responsiveness of human eccrine sweat glands to intradermally injected choline and carbachol was studied in vivo using a plastic paint impression method. Both drugs exerted consistent dose-related effects, choline being significantly less potent than carbachol. The responses to both drugs attained a maximum level approximately 3 min after the injection, but the responses to choline had a less pronounced peak and declined more slowly than the response to carbachol. The response to choline, but not the response to carbachol, was antagonised by hemicholinium-3. Young males showed greater responsiveness to both drugs than young females, this being reflected in higher maxima of the dose-response curves obtained for the males. Smaller responses to both drugs were observed in old females than in young females, this being reflected in lower maxima of the dose-response curves obtained for the elderly group. A group of elderly female patients with clinical diagnoses of Alzheimer-type dementia showed smaller responses to both drugs than the group of non-demented elderly females. The results show that choline can stimulate eccrine sweat glands, possibly by an indirect mechanism involving active uptake and metabolic conversion to acetylcholine. The reduced responsiveness seen in the patients suffering from Alzheimer-type dementia could reflect either a loss of function of cholinergic sympathetic neurones or impaired functioning of the sweat glands themselves.
Adult↗
Falls in the elderly: causes and prevention.
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Accident Prevention↗
A retrospective study of chloral hydrate, meperidine, hydroxyzine, and midazolam regimens used to sedate children for dental care.
PURPOSE: The purpose of this retrospective study was twofold: a) to examine the behavior and physiology of pre-school children each sedated with 1 of 3 drug regimens based on patient age, dental needs, and pre-operative clinical impression; and b) to determine the association between pre-operative behaviors to the behavior and physiology of the sedated children. METHOD: Records of more than 600 patients sedated at Columbus Children's Hospital dental clinic over a two-year period were culled for patients who ranged in age from 2 to 5 years of age and had received one of three different drug regimens: a) chloral hydrate and hydroxyzine (CH-H), b) chloral hydrate, meperidine, and hydroxyzine (CH-D-H), or c) midazolam (M). A minimum of 300 patients (100/drug regimen) were randomly selected. The standard sedation sheet used in all sedations at the clinic included, among other factors, pre-operative assessments of patient behavior, interaction, and cooperation. Physiological and behavioral variables during the intraoperative sedation periods were also available. These periods included initial baseline vitals, vitals following drug administration, topical and local drug administration, rubber, dam placement, and a minimum of the first 15 minutes of restorative procedures. The three drug regimens were compared for these variables. Data were entered into SPSS for data analysis using one-way ANOVA, Chi-square, regression analysis, and descriptive statistics. RESULTS: The results indicated significant mean differences in patient age, weight, and duration by drug regimen (F = 20.3, P < 0.001; 16.2, P < 0.001; and 48.7, P < 0.001, respectively). ANOVA indicated a significant difference among drug regimens for percent of quiet, sleeping, and struggling behaviors. Quiet behavior accounted for 26%, 41%, and 67% of all behaviors for CH-H, CH-D-H, and M, respectively. Sleep accounted for 50%, 43%, 0.4% and struggling 11%, 8%, and 19% for CH-H, CH-D-H, and M, respectively. Pre-operative behaviors were also significantly different and patient cooperation was the only variable found minimally predictable of intra-operative behaviors (R = 0.32, P < 0.001). Significant differences among drug regimens were found for heart rate (HR) and mean arterial blood pressure (MAP) during certain procedures (e.g., CH-H produced lower MAP compared to the other drug regimens); however, all physiological variables were within normal limits for the children. CONCLUSION: Significant differences were found for behavioral and physiological variables among the drug regimens (e.g., CH-D-H produced significantly more quiet and sleeping behaviors than M). Prospective studies are needed to confirm these findings.
Analysis of Variance↗
Endometriosis: a comparison of associated disease histories.
We examined a subgroup of 43 women with endometriosis who reported family members affected by the disease. A matched group of female friend-controls (n = 43) was used for comparison, and reports of selected autoimmune diseases, infectious diseases, and allergic manifestations were compared. For this subset of women, there appeared to be a strong familial tendency to allergic manifestations. Vaginal yeast infections, a history of mononucleosis, eczema, hayfever, and food sensitivities were reported to occur much more frequently for these women. All statistical tests on these conditions were significant at the .05 level of probability or less.
Acute Disease↗
Effect of positioning of postoperative fractured-hip patients as related to comfort.
Twenty-three elderly patients, who had experienced repair of a fractured hip with Richards' compression nail and plate,were surveyed in a midwestern general hospital over a four and one-half month period. This study, which measured which position best maintained comfort postoperatively for these patients, demonstrated that the best way of positioning patients was not always as perceived by nurses. The study also correlated positioning with body weight and with sleeping side habit. Findings verified previous research on pain and nursing comfort measures. The quality of nursing care can be demonstratively improved when the diagnosis of these elderly patients is not allowed to preclude the provision of appropriate therapy and nursing care.
Aged↗