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Biomedical subjects

K L Geoly

Publications and source records attributed to K L Geoly.

5 recordsLinked to original sources

Forecasting thrombosis of vascular access with Doppler color flow imaging.

A noninvasive technique, color Doppler flow imaging, was used to study the predictive value for future episodes of thrombosis in vascular access (polytetrafluoroethylene [PTFE] grafts and radial-cephalic fistulae) in a series of chronic hemodialysis patients. Patients with grafts were classified into three groups based on maximum constriction of the vascular access diameter: narrowing of greater than 50% (group I), narrowing of 30% to 50% (group II), and no narrowing or narrowing less than 30% (group III). More than half of the patients in group I suffered vascular access thrombosis within 6 months, while only 9% to 13% of patients in groups II and III had episodes of thrombosis during the same time interval. Decreased access volume flow (AVF) also correlated with episodes of thrombosis in these patients. No correlation could be demonstrated between recirculation and future thrombosis. No patient with a fistula had narrowing greater than 30% and none had vascular access thrombosis during the 6-month follow-up.

Arteriovenous Shunt, Surgical

Identification of atypical calcium oxalate crystalluria following ethylene glycol ingestion.

A case of ethylene glycol poisoning was associated with heavy crystalluria unidentifiable by light microscopy. Extensive analysis utilizing scanning electron microscopy, x-ray fluorescence, and diffraction method revealed that the sediment contained calcium oxalate monohydrate in one crystallographic phase. Newest diffraction data for identification of the various forms of calcium oxalate, along with the photographs of the crystals by light and electron microscopy, are included. Fifty cases of ethylene glycol poisoning were reviewed to ascertain the most common form of calcium oxalate crystalluria. The search revealed scanty morphologic data associated with the calcium oxalate crystalluria; however, numerous forms were reported. It is concluded that calcium oxalate crystalluria following ethylene glycol ingestion may assume many forms, which should be recognized to facilitate the rapid diagnosis of ethylene glycol ingestion.

Adult

Treatment of severe drug overdosage with charcoal hemoperfusion.

Mortality from severe poisoning remains excessively high in patients managed conservatively. In this report, charcoal hemoperfusion was used as a therapeutic aid to active drug removal in 10 patients (9 of whom were in Grade IV coma) intoxicated with a variety of drugs and a further 3 patients poisoned with the highly lethal herbicide, paraquat. All 10 patients who ingested drugs recovered. One of the 3 patients ingesting paraquat survived. The hemoperfusion treatments were associated with demonstrated drug removal. Complications associated with hemoperfusion were minor. Decreases in platelet levels were observed but were not accompanied by clinically important bleeding. The technique of hemoperfusion is simple and provides a therapeutic aid in the care of the severely poisoned patient.

Adolescent