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Biomedical subjects

K L Cheung

Publications and source records attributed to K L Cheung.

At least 109 records · Page 6Linked to original sources

Acute scrotal swelling: a sign of neonatal adrenal haemorrhage.

Two neonates presented with acute scrotal swelling suggestive of testicular torsion. Surgical exploration in one patient revealed an infected haematoma. Subsequent investigations including ultrasonography and urinary catecholamine determination disclosed adrenal haemorrhage as the cause of the scrotal haematoma. A second patient in whom a purplish discolouration of the right hemiscrotum was noted was also investigated with ultrasonography, which revealed a normal right testis and a right adrenal haematoma. Both cases of adrenal haemorrhage resolved spontaneously on conservative treatment. Adrenal haemorrhage should be considered as a possible cause of acute scrotal swelling in neonates. Ultrasonography assessment should be performed in such cases to examine the intra-abdominal organs especially the adrenal glands.

Abscess↗

Congenital Candida pneumonia in a preterm infant.

A 24 week gestation survivor of congenital Candida pneumonia who received prompt antifungal treatment and modern neonatal intensive care is reported. It was an unusual case in that fungal chorioamnionitis occurred without a foreign body in the maternal genital tract. Early diagnosis and treatment of congenital fungal pneumonia was possible because of prior knowledge of the obstetric history. Amphotericin B was successfully used for the treatment of this condition but combination with fluconazole (a fungistatic agent) was unsatisfactory and may be undesirable. Dexamethasone therapy to assist extubation was instituted once the fungal infection had been successfully controlled.

Bronchopulmonary Dysplasia↗

Congenital listeriosis: case reports and review of literature.

Four babies with congenital listeriosis were diagnosed in the Prince of Wales Hospital in Hong Kong in 1990-1991. Two died in the early neonatal period. The remaining 2 survived and recovered with no sequelae. The clinical and pathological features of these babies, together with those reported in the recent literature are highlighted so as to raise a high index of suspicion toward this disease and hopefully prompt treatment can be offered.

Adult↗

Interaction of hereditary spherocytosis and alpha thalassaemia: a family study.

We report here a family of patients with coexistent hereditary spherocytosis and alpha-thalassaemia. The different clinical presentations of the family members were affected by the severity of the alpha-thalassaemia. The haemolytic effect of hereditary spherocytosis was modulated by the increased osmotic resistance of thalassaemia in the patients with both disorders. Coexistence of haemoglobin H disease and hereditary spherocytosis resulted in an asymptomatic state. In contrast, coexistence of alpha-thalassaemia trait and hereditary spherocytosis was still haemolytic. The different shapes of the osmotic curves in the family members correlated with the severity of their symptoms.

Child↗

Dextrocardia with single coronary artery ostium in a patient with aortic regurgitation and supraventricular tachycardia. A case history.

A sixty-year-old man who presented with dyspnea and palpitations was investigated in this institution and was found to have dextrocardia, single aortic coronary ostium, severe aortic regurgitation, and atrioventricular nodal reentrant tachycardia. The association of single aortic coronary ostium and this combination of cardiac abnormalities has not been previously reported.

Amiodarone↗

Effect of percutaneous balloon mitral valvuloplasty on serum creatinine phosphokinase MB-isoenzyme levels.

Twenty-one patients with moderate to severe mitral stenosis were treated with percutaneous balloon mitral valvuloplasty (PBMV) using Inoue mitral double-lumen balloon catheters. Creatinine phosphokinase MB isoenzyme (CPK-MB) levels were measured at baseline, 5 min, 6 h, and 18 h post dilatation. Haemodynamic indexes, 12-lead ECGs, and 2-dimensional echocardiograms were performed to evaluate systolic function postprocedure. CPK-MB levels were modestly increased at 5 min and at 6 h postprocedure compared with the baseline level (p < 0.001) but were still within the normal reference range, except for one patient who had a level at 5 min minimally above the upper limit of normal. CPK-MB levels were not significantly increased at 18 h after the procedure. No significant changes in ejection fractions, 12-lead ECGs, and regional wall motion occurred in any of the patients studied. In conclusion, PBMV causes modest early elevation of CPK-MB. This elevation is not associated with changes in LV systolic function and does not interfere with the diagnosis of acute myocardial infarction using the enzyme elevation criteria.

Adult↗

Percutaneous balloon mitral valvotomy in pregnancy using the Inoue balloon catheter.

Percutaneous balloon mitral valvotomy (PBMV) using the Inoue balloon catheter was performed successfully in 2 patients with severe mitral stenosis refractory to medical treatment during pregnancy. Because of its unique design and ease of manipulation, we recommend the Inoue balloon catheter for performing PBMV in selected patients with mitral stenosis during pregnancy, as procedure and fluoroscopy times can be significantly shortened.

Adult↗

Angiographic visualization of 'tumour vascularity' in atrial myxoma.

Nine patients with atrial myxoma in whom selective coronary arteriography had been performed were studied. The angiographic sign of 'tumour vascularity' was found to be present in three patients with highly vascularized atrial myxoma. The clinical significance of the angiographic sign is unknown although highly vascularized myxomata appear to have a greater propensity to bleeding into the tumour, resulting in an acute worsening of clinical symptoms. The angiographic sign of 'tumour vascularity' is not specific but useful to complement the diagnosis of an atrial myxoma. The indication for selective coronary arteriography in patients with atrial myxoma remains the detection of coronary artery disease, thus concomitant coronary artery bypass surgery could be planned preoperatively.

Aged↗

Venous thrombosis after long-term transvenous pacing in the Chinese.

To determine the incidence of venous thrombosis after long-term transvenous pacing in the Chinese, venograms were performed in 50 consecutive Chinese patients seen at the pacemaker clinic. There were 25 women and 25 men. The mean age was sixty-six years (range thirty-two to eighty-one). The indications for pacing were complete heart block in 16 patients and sick sinus syndrome in the remainder. All pacemakers were of the single-chamber ventricular pacing type and had been implanted for a mean period of four years (range two to seven). In 27 patients the route of entry for the pacing electrode was through the cephalic vein and in the other 23 patients the subclavian veins were used. Of the 50 venograms, 1 showed partial and 1 showed total obstruction at the subclavian vein. Both patients (4%) were asymptomatic. All others (96%) were normal. The incidence of venous thrombosis was not related to the routes of entry of the pacing electrodes. All patients tolerated the procedure well and had no complications. It is concluded that the incidence of venous thrombosis after long-term transvenous pacing is extremely low in the Chinese (4%), and venograms are both safe and useful for identifying venous thrombosis related to transvenous pacing.

Aged↗