Biomedical subjects
K Kristensen
Publications and source records attributed to K Kristensen.
LSD-TREATMENT. EXPERIENCE GAINED WITHIN A THREE-YEAR-PERIOD.
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Epidemiology of Haemophilus influenzae type b infections among children in Denmark in 1985 and 1986.
A retrospective epidemiological study of invasive Haemophilus influenzae type b infections among children in Denmark 1985 and 1986 was carried out and 226 cases were identified. Of these 93% occurred in patients younger than five, corresponding to an annual incidence of 40 cases per 100,000 children aged 0-4 years, 68% occurred in patients younger than two years of age, and 6% in patients younger than six months. The annual incidences of meningitis and epiglottis were 27 and 8 cases, respectively, per 100,000 children aged 0-4 years. Of the 156 cases with meningitis four patients died and seven had severe neurological sequelae. Only 67% of the cases of meningitis had been notified.
Denitrification losses from outdoor piglet production: spatial and temporal variability.
Animal welfare considerations have stimulated the development of outdoor piglet (Sus scrofa) production systems, but the high levels of nutrients excreted suggest that nutrient losses from this system may be high. This study first described the spatial distribution of denitrification activity in a 5- x 5-m grid within and outside a paddock immediately after the sows (32 sows ha(-1) for 6 mo) were removed in October 1997, and again the following March. Denitrification rates averaged 0.01 kg N ha(-1) d(-1) outside, and 0.5 kg N ha(-1) d(-1) inside the paddock in October, while the corresponding figures in March were 0.01 and 0.1 kg N ha(-1) d(-1). The highest denitrification rates were observed around the feeder, and this was also the case for concentrations of dissolved organic C and inorganic N in the soil. A statistical model that included both soil parameters and distance to feeder and huts gave the best description of the variability, but there was no significant autocorrelation between sampling points. In a second phase, seasonal variation of denitrification activity within a paddock (12 sows ha(-1) yr(-1)) was quantified; 10 soil cores were sampled along a transect 11 times between March 1998 and February 1999. There was a significant positive effect of dissolved organic carbon (DOC) on denitrification at <25% gravimetric soil moisture (i.e., to November in this study). Both climate and management (position of huts and feeder) appeared to influence denitrification, which was estimated to be 69 kg N ha(-1) yr(-1), or 11% of the N surplus of this production system.
Trace element status in alcoholism before and during disulfiram treatment.
Trace element status was ascertained in 19 alcoholic patients under long-term treatment with disulfiram and in 12 alcoholic patients treated for the first time; the latter group was re-examined after four weeks of treatment. Both groups were compared to matched controls with a moderate alcohol intake. The copper/zinc ratio in serum was increased in the patients under long-term treatment, and a significant decrease occurred during the first four weeks of treatment in the second group. Blood lead was slightly increased in the second group, but not in the patients under long-term treatment. Blood cadmium was high in both groups, perhaps related to excessive tobacco smoking. Blood mercury concentrations were uniformly low. Urinary nickel excretion in the first group was above reference values, and an increase was seen in the second group during the treatment period. Although trace element concentrations in body fluids may not reflect tissue levels, the results support the notion that trace element balances are influenced by alcoholism and disulfiram treatment.
Vitamin D deficiency in pregnant and breast-feeding women and their infants.
We describe the cases of five consecutive infants with symptomatic vitamin D deficiency and their mothers. Four of the infants were light skinned, all had poor sunlight exposure, and all were breast-fed or had diets low in vitamin D. All mothers had vitamin D deficiency. Regardless of race, infants with poor sunlight exposure and diets lacking in vitamin D are at risk for vitamin D deficiency. Mothers of these infants should be evaluated for vitamin D deficiency. Vitamin D supplementation of the breast-feeding mother at risk and her infant is recommended.