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Biomedical subjects

K Kleinmann

Publications and source records attributed to K Kleinmann.

14 recordsLinked to original sources

Harvey A. K. Whitney Lecture. We really do care.

The evolution of pharmacy as a caring profession is discussed. Pharmacy has always been a caring profession. However, the focus of that caring has shifted over time. During the compounding and manufacturing era of the 1950s, pharmacists expressed their caring by preparing drug products in accordance with stringent quality-control procedures. The unit dose era saw pharmacists caring by seeking to eliminate unnecessary nursing manipulations, ensuring that patients received their drugs, and decreasing the medication error rate. The clinical pharmacy era had pharmacists providing drug information and monitoring pharmacokinetics. Until recently, activities centered on the drug and were geared primarily to the physician or to economics. Today, dissemination of the philosophy of pharmaceutical care is causing pharmacists to take full responsibility for actions devoted to ensuring the best possible outcomes of drug therapy for the least cost. Pharmaceutical care has become pharmacy's mandate. But pharmaceutical care cannot be embraced with rhetoric and changed departmental names alone; it must be practiced. Under pharmaceutical care, pharmacists are gaining more prescribing authority. Pharmaceutical care also offers the opportunity for greater continuity of care and broader professional unity among pharmacists. Pharmacy has always progressed most during times of adversity like these. Pharmacy must strive to uphold the profile of the department, and pharmacy directors must maintain their leadership, along with their ability to practice on the front lines. Pharmacists should continue to demonstrate their value to physicians and administrators. Residency programs must not neglect the mentor-resident relationship, as this nourishes the development of future leaders.(ABSTRACT TRUNCATED AT 250 WORDS)

Awards and Prizes

Antibiotic cost control measures in a hospital pharmacy.

Faced with rising drug costs and an increase in type-1 beta-lactamase resistance, hospitals have been looking for ways to contain antibiotic costs while continuing to provide quality medical care. The hospital pharmacy at Montefiore Medical Center, Moses Division, has developed a number of programs aimed at identifying antibiotic prescribing trends and minimizing costs. An antimicrobial susceptibility cascade reporting (ASCR) system is used to consolidate and target antimicrobial susceptibility information available to the staff physicians. All antibiotics are tested in the microbiology laboratory for susceptibility; however, physicians receive susceptibility reports only for the more cost-effective, conventional antibiotics. Broader-spectrum, more powerful, and usually more expensive antibiotics are not reported with the ASCR system unless resistance to the more cost-effective antibiotics is noted. Two other reforms initiated are expansion of the pharmacy-based intravenous additive program to include antibiotics and the implementation of a drug therapy enhancement program authorizing automatic conversion by the pharmacist of targeted drug regimens to more clinically rational, cost-effective regimens.

Anti-Bacterial Agents

Controlled study of the impact of educational home visits by pharmacists to high-risk older patients.

Lack of information about medications coupled with high rates of utilization complicates compliance with medication regimens and increases the risk of adverse effects among older adults. We undertook a study of the efficacy of community-based interventions by pharmacists in a randomly-allocated one-half of a sample of 284 older adults considered to be at high risk for medication-related problems. Information and attitudes towards prescription and over-the-counter medications did not differ significantly between the intervention and comparison groups, either before or after the pharmacist interventions. However, visits to physicians were significantly less in the intervention group, suggesting an important if unexpected impact on health-related behavior.

Aged

P & T Committee roundtable discussion: Eastern region. Part I.

A series of regional roundtable discussions regarding the successful operation of Pharmacy and Therapeutics (P & T) Committees has been conducted by Hospital Formulary. Representatives from private hospitals, university and teaching hospitals, as well as Veterans Administration medical centers discuss committee profile, constituency, function, mechanics, and criteria for establishing a successful formulary within an institution. The sessions were taped, and the edited transcription is provided in the following article.

Hospitals

P & T Committee roundtable discussion: Eastern region Pt. II.

A series of regional roundtable discussions regarding the successful operation of Pharmacy and Therapeutics (P & T) Committees has been conducted by Hospital Formulary. Representatives from private hospitals; university and teaching hospitals, as well as Veterans Administration medical centers have participated to ensure that different aspects of P & T Committee performance are demonstrated. issues regarding committee profile, constituency, function, and mechanics are discussed, as are criteria for establishing a successful formulary within an institution. The sessions were taped, and the edited transcription is provided in the following article.

Cost Control

Semiquantitative test for iodine vapor above "complexed" iodine solutions.

A test to determine the extent to which free iodine exists in the vapor phase above the surface of "complexed iodine" solutions is described. The procedure is based on the qualitative starch-iodine test. The results can be related to the degree of complexation occurring between the polymer used in the preparation and iodine. Four products were tested: nonylphenoxypoly ethanol-iodine complex; polyvinyl pyrrolidine-iodine complex; popoxamer-iodine complex; and nonylphenoxypoly ethanol and polyvinyl pyrrolidone iodine complex. Free iodine in the vapor phase of the first product was detected in 90 minutes; the time for the other three was five days. For the tincture of iodine control, the time was 30 minutes.

Gases

Meal interference with antibiotics administered orally in hospitals.

A study of 132 hospitals in New York City was conducted to determine: (1) The usual drug administration and meal serving time schedules used; (2) if oral antibiotics recommended to be given on an empty stomach are actually administered with or near meals; and (3) who is responsible for establishing drug administration time schedules. A structured-disguised questionnaire was used and administered via telephone. Results revealed a wide variation of drug administration time schedules and meal serving times. Meal interference with oral antibiotic absorption was defined as a meal that is served less than one hour before or two hours after an oral antibiotic is scheduled to be administered. The incidence of meal interference ranged from 35 percent to 64 percent. The pharmacy and therapeutics committee, more often than any other group or individual (19.2 percent), was responsible for establishing drug administration times. A formal dosage schedule for orally administered antibiotics is recommended as an effort to reduce the incidence of meal interference with antibiotic absorption. Such a schedule developed at one hospital is presented.

Administration, Oral