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Biomedical subjects

K Kitami

Publications and source records attributed to K Kitami.

49 records · Page 3Linked to original sources

[Normal pressure hydrocephalus after subarachnoid hemorrhage--with regard to pathogenesis and factors influencing the efficacy of shunt surgery].

Twenty-four adult cases of suspected normal pressure hydrocephalus (NPH) after subarachnoid hemorrhage (SAH) were investigated clinically from the aspect of predicting the efficacy of the shunting procedure. They consisted of 13 men and 11 women, with the mean age of 55-y-o. In addition to checking neurological signs, pre- and postoperative CT scans, RI (or CT) cisternography and bolus infusion test were performed in each of them. Shunt surgery was done, all of which ventriculoperitoneal shunt, in 17 patients. They were divided into three groups, namely, shunt effective group (A), neurologically unchanged group after surgery (B) and worsened group (C). The A group had 8 cases, B had 8 also and C contained only one. Effectiveness of shunt procedure was measured by an improvement in the activity of daily life (ADL). Compared with group B, group A tended to have more cases of delayed onset of NPH (mean days of 112 from SAH attack in group A while 55 days in group B), cases with "trias" (3 against 0) and moderate ventricular dilatation with periventricular lucency (8 against 2). The finding of delayed clearance in cisternogram did not make an accurate judgement in the efficacy of shunt surgery. By using the bolus method of infusion test, the true cause of shunt non-effective ventricular dilatation was suggested to the disturbance of cerebral blood circulation due to elevation of intracranial venous outflow resistance. This suggestion was elicited by the analysis of pressure response curve gained from the bolus injection, in which group A cases mainly reached the baseline pressure within 22 minutes, but on the contrary group B showed more than 22 minutes as a rule.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Functional prognosis of surgical treatment of craniosynostosis.

Twenty-three cases of craniosynostosis were studied with regard to age at operation, symptoms, operative methods, and long-term results. Long-term results of 20 cases that were followed up for more than 1 year after surgery showed that mental retardation remained in 8 cases; a slight improvement in mental function was observed in only 2 cases. Of the 8 patients with mental retardation, 7 were operated on more than 6 months after birth, 7 showed striking digital impression on skull X-ray films and 5 were suffering from oxycephaly. Of the 8 patients with mental retardation, 5 had suffered from perinatal asphyxia or had seizures during delivery and subsequent past history. From these observations, factors affecting prognosis are: (1) age at operation; (2) the degree and duration of increased intracranial pressure; (3) the extent and degree of suture closures; (4) perinatal asphyxia and seizure disorders.

Child↗

[Angiographic analysis of the middle cerebral artery in cerebral aneurysms--its branching pattern and so-called vascular anomalies].

UNLABELLED: Branching patterns of middle cerebral artery (MCA) were angiographically analyzed in 704 cases with cerebral aneurysms. The mean age was 53 years old and the men-to-women ratio was 1.1. In addition, 13 vascular anomalies of MCA were reported and their correlation with the occurrence of cerebral aneurysm was studied. RESULTS: MCA branching patterns were classified in 6 types. Each type was further studied by dividing into 2 subgroups, namely one with MCA aneurysms at their side and the other without MCA aneurysms. There were no differences statistically between each two groups. Vascular anomalies were consisted of 5 duplications of MCA, 4 fenestrations, 3 accessories and one case of combination of duplication and accessory in the same side. Duplications and accessories did not have any evidence of developing aneurysm more frequently at their bifurcation than any one of normal MCA branching patterns. So we concluded that duplications and accessories should be thought to have similar meanings with the ordinary branching patterns of MCA in the occurrence of aneurysms. A postmortem case of accessory MCA without aneurysm revealed that the origin of the anomaly was pathologically normal. We suggested that the origin of accessory MCA could both be an enlarged Heubner artery and a rare branching pattern of MCA. The fenestration should be a true anomaly but at this point we do not have any suggestive clue for that. Finally, we thought that the combination of duplication and accessory in a single MCA was very rare morphologically, and worthwhile to report.

Adult↗

[Angiographic analysis of the internal carotid-vertebrobasilar system with cerebral aneurysms--with special interest in the morphological aspect including so-called vascular anomalies].

In a series of 704 aneurysm patients who were admitted to the Research Institute for Brain and Blood Vessels-AKITA during the last 9.5 years (from October, 1974 to March, 1983), angiographic features of the internal carotid-vertebrobasilar system and related vascular anomalies were analyzed with reference to the site of aneurysms. The age distribution was from 20 to 78 years (mean age 53 years) and the men to women ratio was 1:1.1. The total number of the aneurysms was 866. The site distribution of aneurysms consisted of 230 (27%) anterior communicating, 269 (31%) middle cerebral, 282 (38%) internal carotid, 54 (6%) anterior cerebral, 45 (5%) vertebrobasilar and 6 other arteries. More than one aneurysm were found out in 137 cases. The total number of performed cerebral angiograms was 1840, in which right carotid arterial angiograms were 652, left carotid 644 and vertebral 544. Angiographic features of the posterior communicating arteries (Pcom) with or without internal carotid-Pcom aneurysm were compared one side with the other, statistically revealing that the morphological factor of the Pcom did not play an important role in the development of the cerebral aneurysm at this portion. Anomalies of the posterior cerebral artery directly originated from the internal carotid artery were found in 9 cases, and three of them had the aneurysm at their origin. Anomalous carotid-basilar anastomoses were seen in 7 cases, namely 6 persistent primitive trigeminal arteries (2 of them were PTA variants) and one persistent primitive hypoglossal artery.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[Angiographic analysis of the anterior cerebral arteries with cerebral aneurysms--with special interest in the morphological aspect including so-called vascular anomalies].

In a series of 704 aneurysm patients who were admitted to the Research Institute for Brain and Blood Vessels-AKITA for the last 9.5 years (from October, 1974 to March, 1983), angiographic features of the anterior cerebral arteries and related vascular anomalies were analyzed with reference to the site of aneurysms. The age distribution was from 20 to 78 years (mean age 53 years), and the men to women ratio was 1:1.1. The total number of aneurysms was 866. The site distribution of aneurysms consisted of 230 (27%) anterior communicating, 269 (31%) middle cerebral, 282 (38%) internal carotid, 54 (6%) anterior cerebral, 45 (5%) vertebrobasilar and 6 other arteries. More than one aneurysm were found out in 137 cases. The total number of performed cerebral angiograms was 1840, in these right carotid arterial angiograms were 652, left carotid 644 and vertebral 544. Cases were divided into two groups, namely one who had the anterior communicating artery (Acom) aneurysm and the other who had not. Angiographic calibers of A1 portion (proximal portion of the anterior cerebral artery) were compared statistically between these two groups. As a result, three points as below were clarified in this series. 1) The Acom aneurysm group showed the significant asymmetry of A1 (p less than 0.005) compared to the other cases. 2) The left A1 portions were significantly dominant (p less than 0.05) to the right in the Acom aneurysm group. 3) Angiographic hypoplasias and aplasias of A1 were found in the Acom aneurysm group more frequently than in the other with statistical significance (p less than 0.005).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Findings of magnetic resonance imaging in cerebral venous occlusion: difference from hemorrhagic infarction.

A case of cerebral venous occlusion is reported. X-ray computed tomography showed a high-density lesion mimicking an intracerebral hemorrhage. In contrast, magnetic resonance images taken at the early clinical stage revealed a high-intensity lesion in both T1- and T2-weighted images. Follow-up magnetic resonance images at the chronic phase revealed that the intensity of this lesion had changed to low in the T1-weighted image, while still being high in the T2-weighted image. These findings suggest that the lesion might be due to venous congestion produced by cerebral venous occlusion rather than hemorrhage into the cerebral parenchyma.

Cerebral Hemorrhage↗