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Biomedical subjects

K Katz

Publications and source records attributed to K Katz.

71 records · Page 4Linked to original sources

Costovertebral anomalies in osteogenesis imperfecta.

Study of 16 patients with Type III osteogenesis imperfecta showed marked elongation of the pedicles of the vertebrae in all cases, a deformity which was not seen in other types of the disease. Posterior rib angulation was also noted in Type III disease. These features have proved useful in suggesting the diagnosis of osteogenesis imperfecta even before long bones have fractured and in categorizing patients with osteogenesis imperfecta into the correct type for prognostic purposes.

Biomechanical Phenomena↗

The natural history of schizophrenia: a 5-year prospective follow-up of a representative sample of schizophrenics by means of a standardized clinical and social assessment.

A comprehensive, representative cohort of 121 schizophrenics from a delimited catchment area, hospitalized in the course of 20 months (1973--4) and who met PSE criteria, was collected for a therapeutic trial (1976--6) in which, during the year after discharge, standardized clinical and social assessments has been made by personal interview at home. Standardized observations were repeated 4 years later. Follow-up was 99% complete. 48% of the cohort and 58% of the first admissions had a good outcome. Females fared significantly better than males.

Clinical Trials as Topic↗

Surgical treatment of spinal meningiomas.

A review is presented of 44 cases of spinal meningioma. Analyses of the data collected indicated that early diagnosis may prevent irreversible neurological deficit and enhances the chance for full recovery after operation. The results obtained in elderly patients were very encouraging. The difficulties involved in making a correct early diagnosis are stressed. The finding of scoliosis in 40 per cent of the patients is noteworthy.

Adult↗

End-bearing characteristics of patellar-tendon-bearing prosthesis--a preliminary report.

The present work was aimed at investigating the degree of participation of the stump end in the weightbearing process in PTB prostheses. Despite the belief that the stump end is not capable of withstanding high loads, it was revealed that most patients can bear from 15 percent up to 45 percent and more of their weight on the stump end. The limited number of patients studied diminishes the statistical significance, but the results of this work do suggest that the weightbearing mechanism of a PTB prosthesis can be further improved by transferring more load through the stump end. It is suggested that a nondestructive technique for assessing the end-bearing efficiency of the prosthesis be developed. Also, the criteria for design of the socket end in order to produce the desired load-bearing features needs further investigation.

Adult↗

Fractures in premature infants.

Fractures not related to birth trauma were diagnosed in 1.2% of preterm infants between the 24th and the 160th day of life. The clinical and radiologic findings as well as the follow-up on 12 preterm infants with one or more fractures were reviewed. Fractures occurred either in the ribs or long bones or both. Their clinical history, the radiographic appearance, and laboratory data suggest that most of the infants may have suffered from bone loss associated with low intake of calcium and phosphorus. Improving the metabolic status and removing the risk factors prevented further fractures and led to good healing.

Bronchopulmonary Dysplasia↗

Irritable hip and Perthes' disease.

One hundred fifty patients with 160 irritable hip episodes and 120 patients with Perthes' disease who were treated between 1976 and 1986 were compared. The ratio of males to females was 2.1:1 for patients with irritable hip and 3:1 for patients with Perthes' disease. On the average, patients with irritable hip were aged 3 years and patients with Perthes' disease were aged 7 years. The duration of symptoms in patients with irritable hip averaged 6 days and 6 weeks in patients with Perthes' disease. One patient developed Perthes' disease 2 months after the irritable hip episode. The mean intraarticular pressure in 10 of the hip patients was 17 mm Hg in the neutral flexion/extension position. The pressure decreased to a mean of 7 mm Hg at 90 degrees of flexion and increased to 10 mm Hg at 45 degrees and to 16 mm Hg at 30 degrees of flexion. There was a positive correlation between the amount of aspirated fluid and recorded intracapsular pressure. Pressure tamponade in the irritable hip syndrome is probably not responsible for Perthes' disease.

Adolescent↗

Effect of neonatal posture on later lower limb rotation and gait in premature infants.

The rotational profile of 265 children age 4-8 years who were born at the gestational age of less than or equal to 30 weeks and were nursed prone for several months after birth showed a marked outtoeing gait up to the age of 6 years. Their positive thigh-foot angles were significantly higher than those of the general population. These angles indicate that their outtoeing gaits were caused by marked external tibial rotation.

Age Factors↗

Normal ranges of popliteal angle in children.

Measurement of the popliteal angle is used to assess hamstring contracture in children with cerebral palsy. The popliteal angle in 482 normal children, 1-10 years of age, was measured. Using a 360 degrees goniometer, the popliteal angle was measured with the hip held at 90 degrees flexion to indicate hamstring muscle tightness. Between the ages of 1 and 3 years, the mean angle was 6 degrees (range, 0-15). At age 4, the angle rose to 17 degrees in girls and 27 degrees in boys (range, 5-45). At greater than or equal to 5 years the mean angle was 26 degrees with little change (range, 0-50). A popliteal angle of greater than 50 degrees in the above age groups indicates abnormal hamstring tightness.

Cerebral Palsy↗

Normal range of fetal knee movements.

Fetal limb movement abnormalities have been described to date in the literature only in subjective terms. The aim of the present study was to define objectively the normal range of fetal knee motion. The study population consisted of 240 normal fetuses at gestational age 16-39 weeks. The range of active knee motion was determined on routine prenatal ultrasound scans by measuring the angles between the midtibia, midfemur, and midknee on maximum flexion and extension. From 16 to 32 weeks, average knee flexion was 129.4 degrees (range, 120-140 degrees) and average extension was 23.7 degrees (range, 15-40 degrees). From 33 to 39 weeks, there was a gradual decrease in knee extension owing to lack of space in uterus. Knowledge of the normal range of fetal knee motion will assist clinicians in the prenatal diagnosis of neuromusculoskeletal disease.

Female↗

Musculoskeletal deformities in Behr syndrome.

SUMMARY: Seventeen children with Behr syndrome were investigated, focusing on the musculoskeletal deformities and long-term outcome. Behr syndrome is characterized by optic atrophy beginning in early childhood associated with ataxia, spasticity, mental retardation, and posterior column sensory loss. The ataxia, spasticity, and muscle contractures, mainly of the hip adductors, hamstrings, and soleus, are progressive and become more prominent in the second decade. In 70% of the patients, contractures developed in the lower limbs, requiring surgery mainly for the Achilles tendon, hamstrings, and adductor longus. At last follow-up at an average age of 21.7 years (range, 8-31 years), 13 of the patients are housebound walkers, 2 are nonfunctional walkers, and 2 are nonwalkers.

Achilles Tendon↗

Calcaneal ostectomy for Haglund disease.

From 1967 to 1987, operative treatment was performed on 28 feet in 22 patients with retrocalcaneal bursitis due to prominent posterior superior margin of the calcaneus (Haglund disease). Through a lateral or medial approach, the prominent bone was removed. The results indicated that excision of the retrocalcaneal bursa was not necessary. Preoperative planning and intraoperative examination was necessary in order to remove an adequate amount of bone, which was the key for a successful result.

Adolescent↗

Rotational deformities of the tibia and foot in preterm infants.

Metatarsus adductus and medial tibial torsion are common in term infants. Our study shows that metatarsus adductus is rare, whereas medial tibial torsion does not occur in preterm infants with gestational ages of less than or equal to 30 weeks. These preterm infants have lateral rotation of the legs, external tibial rotation, and everted or normal feet at birth. This posture may explain the rarity of metatarsus adductus and medial tibial torsion in preterm infants.

Bone Diseases, Developmental↗

Primary bone tumor resectability: the value of serial MRI studies in the determination of the feasibility, timing, and extent of tumor resection.

We report the prospective analysis of 119 magnetic resonance imaging (MRI) studies in 41 patients with primary bone tumors performed from January 1984 to December 1990 to evaluate the contribution of serial MRI studies in the determination of feasibility, timing, and extent of tumor resection. Long repetition time (TR)-long echo time (TE) T2-weighted (T2, second echo) imaging was the most useful in assessing soft-tissue involvement, and short TR-short TE T1-weighted (T1) imaging for documenting the bone marrow changes. The feasibility, timing, and extent of resection was determined with the help of MRI in 20 cases with only two local recurrences. One study falsely suggested active tumor. In four other cases, a treatment decision was made based on the MRI. The MRI added significantly to the evaluation by computed tomography, radiographs, and bone scans.

Adolescent↗

The contribution of prenatal sonographic diagnosis of clubfoot to preventive medicine.

From 1995 through 1997, clubfoot was detected by transabdominal sonography in 13 fetuses of 12 women, in nine bilaterally and in four unilaterally (total, 22 clubfeet). The average menstrual age at diagnosis was 23.6 weeks (range, 17-36). Three fetuses had associated malformations: two were therapeutically aborted and one died 2 weeks after birth. Proper understanding of the significance of prenatal ultrasound findings of clubfoot will assist both the orthopaedist and the parents in reaching a decision concerning future management of their pregnancy.

Clubfoot↗

Below-knee plaster cast for the treatment of metatarsus adductus.

Sixty-five infants with moderate (37 feet) or severe (48 feet) inflexible metatarsus adductus were treated with a below-knee plaster cast. The deformity was corrected in 6-8 weeks in all cases. At the 2- to 6-year follow-up (mean, 4 years), the correction was maintained in all children who had had a moderate deformity; of the 44 feet with severe deformity that were available for examination, six now had a moderate deformity, and one a severe deformity. All forefeet were flexible, and further treatment was unnecessary. Our results are similar to those for above-knee plaster casts. We conclude that a below-knee plaster cast is effective in the treatment of metatarsus adductus.

Casts, Surgical↗