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Biomedical subjects

K Kates

Publications and source records attributed to K Kates.

7 recordsLinked to original sources

Response covariation. The relationship between correct academic responding and problem behavior.

This article examined the relationship between the accuracy of academic responding and aggression for two boys with mild mental retardation. Their teacher reported low rates of correct responding and high rates of aggressive behavior during spelling instruction. A functional analysis showed that aggression was escape maintained. Following the functional analysis, participants were tested on relations between printed, photographic, and dictated stimuli corresponding to their spelling words. On pretests, they were unable to match printed words to their photographs or to their dictated names; they could neither name the printed words nor spell the photographs or dictated words. High rates of aggression were observed during the pretests. The participants then were taught the letter-by-letter construction of the appropriate words when shown photographs. On posttests, the participants correctly matched printed words to their photographs and dictated names. In addition, they correctly named printed words and spelled dictated words orally. Data showed that rates of problem behavior negatively covaried with improvements in the participants' academic responding.

Achievement↗

Assessment of stimulus generalization gradients in the treatment of self-injurious behavior.

Descriptive and experimental analyses suggested that the self-injurious behavior (SIB) of a 10-year-old girl with severe mental retardation was maintained by attention. Additional analyses identified physical contact as the type of attention maintaining SIB; therefore, we hypothesized that physical proximity of an adult was a discriminative stimulus for SIB. Based on these findings, we systematically varied the distance between the participant and a therapist to assess stimulus generalization. Results showed that rates of SIB varied relative to the distance between the participant and therapist; the highest percentage of SIB occurred with the therapist positioned less than 0.5 m from the participant. Treatment consisted of placing the therapist at a specified distance (9.0 m) from the participant (during low-attention situations), noncontingent reinforcement, and extinction.

Behavior Therapy↗

The effect of reinforcer preference on functional analysis outcomes.

We combined functional analyses and concurrent-schedule assessments to identify reinforcer preference during situations in which problem behavior may have been multiply controlled. Participants were 3 children with developmental delays who engaged in problem behavior during toy play with another child and one adult present, suggesting that problem behavior may have been maintained by adult attention or access to tangible reinforcement. Thus, conditions were designed to test attention and access-to-toys hypotheses. Initial functional analyses suggested multiple control. Subsequent concurrent-schedule assessments identified preference between the reinforcers, and treatments were based on these findings. Findings are discussed regarding the assessment of potentially multiply controlled problem behavior.

Adult↗

Noncontingent reinforcement as treatment for severe problem behavior: some procedural variations.

Noncontingent reinforcement (NCR) as a treatment for problem behavior has typically included (a) continuous access to reinforcers at the onset of treatment and (b) extinction. We extended research on NCR by conducting a three-phase preliminary investigation of these components. In Phase 1, a functional analysis showed that the problem behavior of 3 participants with developmental disabilities was maintained by tangible positive reinforcement. In Phase 2, treatment started with the initial NCR interval based on the latency to the first problem behavior during baseline. In Phase 3, treatment consisted of NCR without extinction to determine whether extinction was an essential treatment component. Results showed that the initial NCR schedule based on latency (Phase 2) and NCR without extinction (Phase 3) were effective for reducing rates of problem behavior compared with baseline. Findings are discussed regarding the initial schedule of reinforcement and extinction as components of NCR.

Aggression↗

Rhamnogalacturonan-II, a pectic polysaccharide in the walls of growing plant cell, forms a dimer that is covalently cross-linked by a borate ester. In vitro conditions for the formation and hydrolysis of the dimer.

Rhamnogalacturonan II (RG-II) is a structurally complex pectic polysaccharide present in the walls of growing plant cells. We now report that RG-II, released by endopolygalacturonase treatment of the walls of suspension-cultured sycamore cells and etiolated pea stems, exists mainly as a dimer that is cross-linked by a borate ester. The borate ester is completely hydrolyzed at room temperature within 30 min at pH 1, partially hydrolyzed between pH 2 and 4, and stable above pH 4. The dimer is formed in vitro between pH 2.4 and 6. 2 by treating monomeric RG-II (0.5 mM) with boric acid (1.2 mM); the dimer formed after 24 h at pH 3.4 and 5.0 accounts for approximately 30 and approximately 5%, respectively, of the RG-II. In contrast, the dimer accounts for approximately 80 and approximately 54% of the RG-II when the monomer is treated for 24 h at pH 3.4 and 5.0, respectively, with boric acid and 0.5 m Sr2+, Pb2+, or Ba2+. The amount of dimer formed at pH 3.4 or 5.0 is not increased by addition of 0.5 mM Ca2+, Cd2+, Cu2+, Mg2+, Ni2+, and Zn2+. Steric considerations appear to regulate dimer formation since those divalent cations that enhance dimer formation have an ionic radius >1.1 A. Our data suggest that the borate ester is located on C-2 and C-3 of two of the four 3'-linked apiosyl residues of dimeric RG-II. Our results, taken together with the results of two previous studies (Kobayashi, M., Matoh, T., and Azuma, J.-I. (1996) Plant Physiol. 110, 1017-1020; Ishii, T., and Matsunaga, T. (1996) Carbohydr. Res. 284, 1-9) provide substantial evidence that this plant cell wall pectic polysaccharide is covalently cross-linked.

Barium↗

Functional analysis and treatment of eye poking with response blocking.

A functional analysis of eye poking by a 4-year-old female with severe disabilities and visual impairments showed that high rates occurred in all conditions. We conducted a series of probes to identify the maintaining variable for eye poking following an undifferentiated functional analysis. Results showed that eye poking decreased only when we interrupted finger-eye contact by blocking the response.

Behavior Therapy↗

Reducing escape behavior and increasing task completion with functional communication training, extinction, and response chaining.

The effects of functional communication training, extinction, and response chaining on 3 subjects' escape-maintained aberrant behavior were evaluated using a multielement design. Functional communication training consisted of teaching subjects a verbal response that was functionally equivalent to their aberrant behavior. Subjects initially were allowed to escape from a task contingent on the trained verbal response. In subsequent treatment phases, escape was contingent on the trained verbal response plus the completion of the specified number of steps in the task (response chaining). The number of steps was increased until a subject completed the task to obtain a break. Results showed that the treatment reduced rates of aberrant behavior and that the chaining procedure was effective in decreasing the availability of escape.

Adolescent↗