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Biomedical subjects

K Kapila

Publications and source records attributed to K Kapila.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

Gravid adult female worms of Wuchereria bancrofti in fine needle aspirates of soft tissue swellings. Report of three cases.

Gravid adult female worms of Wuchereria bancrofti were observed in fine needle aspirates of soft tissue swellings from three patients. An inguinal lymph node was aspirated in two cases, and a breast nodule was the site of aspiration in the third case. In one of the inguinal lymph node aspirates, two adult gravid female worms were identified.

Adolescent↗
PubMedDate not supplied

Value of fine needle aspiration cytology in the diagnosis of testicular neoplasms.

In 403 patients with a clinical suspicion of a testicular neoplasm, fine needle aspiration (FNA) was performed on the scrotal mass in 380 cases and on an extrascrotal swelling in 23 cases. There were 109 unsatisfactory aspirates. Fluid was aspirated in 50 cases, and only normal testicular elements were obtained in 82 cases. The aspirate showed an inflammatory lesion in 104 cases. A diagnosis of malignancy or suspicious for malignancy was given in 52 and 6 cases, respectively. Histopathologic confirmation of malignancy was available for 30 cases, for which the aspirate had been reported as malignant in 23, suspicious for malignancy in 3, unsatisfactory in 2 and negative for malignancy in 2. There were no false-positive FNA cytodiagnoses. No local seeding of tumor by the FNA procedure was observed. Typing of the testicular tumors on the aspirates showed a problem in classifying teratocarcinomas.

Biopsy, Needle↗
PubMedDate not supplied

Fine needle aspiration diagnosis of cysticercosis in soft tissue swellings.

The cytomorphologic criteria for diagnosing cysticercosis in fine needle aspirates are described. A retrospective analysis of aspirates from 62 cases with subcutaneous swellings in various sites showed the presence of the parasite in 25 cases. In another 31 cases, the aspiration smears contained no larval parts, but did contain an inflammatory reaction (consisting of large numbers of eosinophils and palasading histiocytes) suggestive of a parasitic cyst. Corresponding histologic material from 19 of these cases were diagnostic of cysticercosis in 9 cases and suggestive of cysticercosis in 10. However, histology was diagnostic of cysticercosis in six cases that produced acellular aspirates. These results show that fine needle aspiration cytology can diagnose or suggest cysticercosis in many cases, but may be falsely negative in a few.

Animals↗
PubMedDate not supplied

Immunoperoxidase detection of carcinoembryonic antigen in fine needle aspirates of breast carcinoma. Correlation with studies in tissue sections.

The peroxidase-antiperoxidase technique was used to demonstrate the presence of carcinoembryonic antigen (CEA) in fine needle aspirates and the corresponding tissue sections in 50 cases of carcinoma of the breast. The incidence of CEA positivity in the aspiration smears was 76%. A good correlation was observed between the results in the aspiration smears and in the tissue sections: 82% in the initial correlation and 90% when additional tissue sections from four of nine discordant cases proved to be positive for CEA. Five cases remained positive for CEA in the aspiration smears and negative for CEA in the tissue sections. This preliminary data indicates that aspiration smears can be used to demonstrate the CEA status in mammary carcinomas.

Biopsy, Needle↗
PubMedDate not supplied

Fine needle aspiration cytology of alveolar soft-part sarcoma. A case report.

A fine needle aspiration specimen from a mass in the thigh of a 25-year-old woman was submitted for cytologic examination. Malignant cells were found singly and in well-defined nests, resulting in an alveolar pattern. Individual cells were large, with moderate amounts of granular cytoplasm and vesicular nuclei with prominent nucleoli. The aspiration cytology findings plus the clinical setting suggested an alveolar soft-part sarcoma. Histologic and electron microscopic examination of the tumor mass confirmed the diagnosis.

Adult↗
PubMedDate not supplied

Cytologic diagnosis of metastatic germ-cell tumors.

The clinical, pathologic and cytologic findings were correlated in 86 cases of metastatic germ-cell tumors. Although the cytologic features of malignant germ-cell tumors are sufficiently characteristic to make specific cytologic diagnosis possible, the diagnostic accuracy can be augmented with cytochemical stains. It was found that due to recent advances in therapy, cytologic detection of metastases does not necessarily indicate a fatal outcome.

Brain Neoplasms↗
PubMedDate not supplied

Increase in accuracy of typing of carcinoma of the uterine cervix by combined use of histology and cytology.

Seventy-five cases of carcinoma of the uterine cervix were typed by histologic examination of cervical biopsies and cytologic analysis of cervical smears. A complete agreement in typing by the two methods was seen in 60 cases (80.0%). In eight cases (10.7%) cytologic and in seven cases (9.3%) histologic examination was found to be better for typing. In general, cytology was better in identifying keratinizing carcinomas, while biopsy was better in identifying adenosquamous and adenocarcinomas. It is recommended that the typing of carcinoma of the cervix should be based on the results of both cytology and histology.

Adenocarcinoma↗
PubMedDate not supplied

Cytologic detection of parasitic disorders.

Parasitic diseases are common in developing countries; yet they are infrequently diagnosed in cytologic material. Six cases are described where routine cytologic examination identified the parasites and suggested the diagnosis. There were three cases of Entamoeba histolytica infection of the female genital tract and one each of hydatid cyst of the brain, Strongyloides stercoralis infection of the lung and filarial infection of the urinary bladder. To our knowledge, cytologic diagnosis of hydatid cyst of the brain and filarial infection of the urinary bladder has not been previously reported.

Adult↗
PubMedDate not supplied

Cystic change in lymph nodes with metastatic squamous cell carcinoma.

A retrospective analysis was performed of the gross characteristics of aspirated material in 335 consecutive cases of metastatic squamous cell carcinoma in cervical/supraclavicular lymph nodes seen during a three-year period. In 57 cases (17.01%), 1-2 mL of fluid was obtained. Microscopic examination of cytocentrifuge smears in all cases showed malignant squamous cells. Cystic change in lymph nodes harboring metastatic squamous cell carcinoma was frequently associated with a tongue primary (21/58 cases, 36.2%) followed by an esophageal primary (4/16 cases, 25%). The frequency of cystic change varied from 9.1% to 21.5% with primaries in the oral cavity, nasopharynx, lung, uterine cervix and unknown sites.

Biopsy, Needle↗