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Biomedical subjects

K Kadonosono

Publications and source records attributed to K Kadonosono.

22 records · Page 2Linked to original sources

Effect of intracameral anesthesia on the corneal endothelium.

PURPOSE: To evaluate the effects of intracameral anesthesia on the corneal endothelium. SETTING: Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Japan. METHODS: This study comprised 24 eyes of 12 white rabbits. One eye of 3 rabbits each was injected with preservative-free lidocaine at concentrations of 0.02, 0.2, or 2% and the fellow eye injected with balanced salt solution (BSS) as a control. The anesthetic agent was injected into the anterior chamber using a bimanual technique. Immediately after enucleation, the cornea was examined by scanning electron microscopy. RESULTS: Scanning electron microscopy revealed no abnormal findings in the eyes injected with lidocaine 0.02 or 0.2% when compared with eyes in the control group. Scanning electron microscopy of the eyes injected with lidocaine 2% showed irregular hexagonal endothelial cells and a significant loss of microvilli. CONCLUSION: Intracameral anesthesia with high concentrations of lidocaine risks corneal endothelial damage but at the low concentration usually used in cataract surgery did not appear to have an adverse effect.

Anesthesia, Local↗

[Corneal sensitivity after cataract operation by corneal incision or scleral incision].

We studied postoperative corneal sensitivity after cataract operation by scleral incision (30 eyes) or corneal incision (29 eyes). Corneal sensitivity was evaluated at 5 points of the cornea with a Cochet & Bonnet esthesiometer at 3 and 6 months after operation. Total value of corneal sensitivity decreased by 60 +/- 5.0 mg/S (mean +/- deviation) 3 months after corneal incision and by 46 +/- 4.1 mg/S after scleral incision. At 6 months after operation, the total value of corneal sensitivity was deceased by 14.0 +/- 2. 5 mg/S in corneal incision cases and by 7.9 +/- 2.0 mg/S in scleral incision cases. Corneal sensitivity after operation was decreased more by corneal incision than by scleral incision.

Aged↗

[A case of Duane's syndrome with ocular melanosis].

Duane's syndrome has various ocular and systemic abnormalities. We report a Duane's syndrome patient with ocular melanosis. Duane's syndrome has many complications, but ocular melanosis has never been reported previously. It is possible that there is a similar mechanism between the ocular melanosis and misdirection of the oculomotor nerve to the external rectus in this case, but it is more probable that it is simply coincidental.

Child↗

Iris neovascularization after vitrectomy combined with phacoemulsification and intraocular lens implantation for proliferative diabetic retinopathy.

PURPOSE: To analyze the incidence of iris neovascularization after vitrectomy combined with phacoemulsification and intraocular lens (IOL) implantation using a small incision in the treatment of proliferative diabetic retinopathy (PDR). PATIENTS AND METHODS: We studied a consecutive series of 46 eyes in which vitrectomy combined with phacoemulsification and IOL implantation had been performed, and compared the surgical results with a prior series of 40 eyes in which vitrectomy alone had been performed. RESULTS: Postoperative iris and angle neovascularization was found in 6 eyes (15%) treated by vitrectomy alone, but in only 1 eye (2%) treated by combined vitrectomy (P<0.05). Final visual acuity improved by two or more lines in 23 eyes (57%) in the vitrectomy alone group, and in 35 eyes (76%) in the combined vitrectomy group. CONCLUSIONS: The incidence of postoperative rubeosis iridis was significantly lower, and the visual results were satisfactory with vitrectomy combined with phacoemulsification and IOL implantation for PDR. These findings suggest that combined vitrectomy for PDR is a useful surgical procedure.

Adult↗