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Biomedical subjects

K Junghanns

Publications and source records attributed to K Junghanns.

At least 37 records · Page 2Linked to original sources

[Is professional autonomy of value? From the viewpoint of the medical director].

Professional independence is one of many steps to a self-sufficient personality. Especially for surgeons who are used to working directly and independently during operations, professional independence is important. It is best achieved in a private surgical office. The chief position in a hospital also guarantees a certain independence. Professional independence is limited by many political and financial restrictions. Nevertheless, every surgeon should try in his own area to reach as much independence as possible. Even in a subordinate position, one can achieve a personally satisfying degree of independence by special surgical skills and knowledge.

Attitude of Health Personnel↗

[Assessment of therapy outcome within the scope of quality assurance in a psychiatric clinic. A report of experiences].

A recent modification of German law requires quality assurance of inpatient treatment, i.e., of the quality of therapy, allowing comparison of different hospitals. In this paper a program developed to assess the outcome by means of international, frequently applied psychopathometric scales is presented. This program was evaluated in a study of 258 psychiatric inpatients. This study emphasized the identification of patients with long-term hospitalization and/or worse outcome. A concept to disclose these so-called 'problematic' patients by means of easily administered scales like the SCL90-R, GAF and WHO-Disability-Diagnostic-Scale (DDS) has been developed. Patients with a very long hospital stay (> 70 days) show a higher number and more severe symptoms in the self-rating (SCL90-R) at admission than the subjects with a short hospital stay. This pilot study demonstrated that a routine outcome analysis can be used for quality management in psychiatry.

Adult↗

[Efficacy and economics of ambulatory surgery in the hospital].

Ambulatory surgery in the hospital does not reduce the number of hospital beds. Available cases are rare. Patients eligible for office-based surgery are mostly already operated in offices and larger outpatient units. The legal situation regarding postoperative responsibility is difficult. The fees for ambulatory surgery are low and represent no incentive for hospitals and doctors.

Aged↗

[Craving--an adequately defined concept?].

Many addicts report on craving--a strong desire to consume the drugs again. Craving is attributed by many addicts to be the main reason for relapse or for the failure to become abstinent. In the recent years some drugs with an "anti-craving" effect have been developed. In this context a review of the complex concept "craving" seems to be urgent. In this paper the psychological conditions of craving and biochemical phenomena possibly underlying craving are reviewed. Basing on the recently available data a new psychobiological concept of craving with two prototypes (craving in early withdrawal and craving during abstinence) has been developed. This model is discussed with regards to possible therapeutic implications.

Alcoholism↗

Endoscopic polypectomy and management of colorectal adenomas with invasive carcinoma.

BACKGROUND AND STUDY AIMS: Invasive carcinoma is found at histology in 2-5% of colorectal polyps removed under flexible endoscopy. The aim of this study was to confirm that histologically complete endoscopic polypectomy under favorable low-risk conditions is sufficient therapy for pT1 carcinoma, while tumors at or close to the margin of the polypectomy, and histological high-risk criteria, require surgical resection with lymphadenectomy. PATIENTS AND METHODS: Eighty-six patients with 87 pT1 carcinomas underwent polypectomy within a twelve-and-a-half-year period. Further treatment prospectively followed the above guidelines. The follow-up was documented. RESULTS: A local tumor residue was found in 5 of 34 patients who had undergone surgical resection for doubtful or incomplete polypectomy. Two patients were found to have nodal disease in the surgical specimen, only one of them harboring a high-risk carcinoma. Two further patients with high-risk carcinomas had tumor progression, despite postpolypectomy resections without local tumor residue or lymph-node infiltration, and died. One patient had a local tumor recurrence on follow-up endoscopy eight weeks after doubtfully complete polypectomy. He underwent resection, and had no further recurrence. No further manifestations of invasive carcinoma occurred after complete polypectomy of 42 patients with low-risk carcinomas. CONCLUSIONS: This study supports the view that complete endoscopic polypectomy is an adequate therapy for low-risk carcinoma: A modification of the follow-up regimen, with less frequent endoscopic controls, is justified.

Adenoma↗

[Treatment of intraperitoneal abscess--ultrasound controlled percutaneous or surgical drainage?].

In a retrospective study the effectiveness of ultrasound guided percutaneous drainage (n = 36) was compared with that of surgery (n = 38) in the treatment of intraperitoneal abscesses. The treatment was successful in 95% while 5% of the patients in both groups died from progressive septic shock; one complication in each group occurred. There is a significant difference in terms of hospital stay (18 vs. 26 days) that favor the percutaneous treatment.

Abscess↗

[Ultrasound-controlled percutaneous drainage of subhepatic liver abscess after conventional cholecystectomy].

From February 1984 to August 1991 subhepatic abscesses were detected by ultrasound in 7 patients with fever following conventional cholecystectomy. Cholecystectomy had been performed in all these patients 6 to 27 days previously. All patients had received antibiotic prophylaxis at the time of cholecystectomy. Three of the 7 patients were at first afebrile, later on again febrile. In the remaining 4 of the 7 patients antibiotic treatment was continued in the face of persistent fever. Percutaneous catheter drainage was performed in all patients. In all of the 7 cases the subhepatic abscesses resolved completely within 10 days to 7 weeks.

Aged↗

[Improved treatment results in advanced gallbladder and bile duct cancer by postoperative combined radiotherapy].

From 1984 to 1990 38 patients had an operation for carcinoma of the gallbladder and bile ducts. The unfavorable prognosis of this type of cancer was improved by a combined treatment, consisting of surgical tumor reduction and implantation of a transhepatic drainage, followed by external radiation and intracatheter brachytherapy. Nine patients were treated in this manner, seven died 6-67 months after operation, two are still alive 7 and 13 months postoperatively.

Adenocarcinoma↗

[Endosonographic tumor staging of gastrointestinal tumors].

In 24 surgical specimens of gastrointestinal tumours the extent of the tumour (T-classification) and the degree of involved lymph nodes (N-classification) were examined. In a preceding study including a subgroup of the cases the high degree of comparability between preoperative endosonography and endosonographic examination of the surgical specimen was demonstrated. The T-classification matched in 75%, an incorrect classification was found in 20%. In 5% the identification of the different layers of the wall was impossible. N-classification was very difficult because of the small amount of identified lymph nodes (25%) and the insufficient sonographic criteria of dignity.

Adult↗

Experimental studies on the effect of duodenal contents on the epithelium of the esophagus.

10 male BD IX rats and 15 male and female Wistar rats weighing between 250 and 300 g had an esophago-jejunostomy according to the method described by Levrat et al. (1962). Four weeks after surgery all 40 animals were sacrificed and examined macroscopically as well as histologically. All animals had deep ulcerative lesions in the lower half of the esophagus associated with hyperplasia, hyperkeratosis and akanthosis.

Animals↗

[Pregnancy and ulcerative colitis (author's transl)].

This is a report on two women (23 and 28 years old) both of them suffering from an exacerbation of a preexisting ulcerative colitis in the second month of their first pregnancy. In one case colectomy and abortion were necessary. The second patient was treated conservatively. An abortion was necessary later on. A study of the literature shows that in most cases an intensive conservative therapy is sufficient to save both mother and child.

Abortion, Induced↗

[Selective induction of tumors in Wistar rats with loop colostomy after administration of methyl-(acetoxymethyl)-nitrosamine (MAOMN) (author's transl)].

A single dose of 7 mg/kg methyl-(acetoxymethyl)-nitrosamine in Wistar rats with double loop colostomy induced adenomas, papillomas, and adenocarcinomas at the site of colostomy in 83% of the treated animals. The mean induction time was 320 days. The pronounced local effect as well as the high tumor yield are discussed in regard to the evident high epithelial sensitivity at the colostomy site.

Adenocarcinoma↗

[Seat belt related abdominal injuries (author's transl)].

Seat belts reduce the severity of trauma in car accidents. There is a definite decrease in the percentage of head injuries, while abdominal lesions seem to increase. Experimental and clinical investigations show a predominance of abdominal wall injuries and liver ruptures. The seat belt syndrome requires close observation of the patient in the intensive care unit. An increasing number of late intestinal obstructions after a seat belt injury due to lesions of the intestinal wall are reported.

Abdominal Injuries↗