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Biomedical subjects

K Jährig

Publications and source records attributed to K Jährig.

At least 19 recordsLinked to original sources
PubMed1992

Transepithelial potential difference in the bronchial system of children with chronic bronchitis and bronchial asthma.

In 45 children with chronic non-specific respiratory diseases (CNSRD), 18 with bronchial asthma and 27 with relapsing or chronic bronchitis, the transepithelial potential difference (tpd) was measured in the tracheobronchial system (bronchoscopy under general anaesthesia). The statistical variation in the tpds was highly significant. In asthmatics with significant eosinophilia in the bronchial secretions of the main bronchus we found a tpd of 26.5 (+/- 8.5) mV and in bronchitics a tpd of 18.2 (+/- 6.3) mV. This suggests that the presence or absence of eosinophils in the secretions, the products of intermediate cell metabolism or different pathogenetic processes, could be responsible for the variety of change in the tpd measured in the respiratory tract.

Adolescent↗
PubMed1991

[Variability of percentile values of body measurements of newborn infants (with special reference to body weight)].

The percentile curves for fetal growth between the 25th and 42nd week of gestation calculated for more than 52,000 newborns in East Germany in 1985 were compared with the rates defined for the same population in 1973-74 and showed a significantly lower mean birth weight. Besides methodological differences (primarily a more precise estimation of gestational age in the new study by using ultrasound fetometry), the differences seem to be mainly the result of changes in the reproductive behaviour of the population over that period (decrease in parity). When comparing different populations independently of ethnic specificities, a number of modifying factors have to be taken into account which significantly influence the birth weight, namely: parity, spacing, age and stature of the mother. These variables have also to be remembered when assessing the maturity of newborns in order to standardize the birth weight in relation to mortality and morbidity. As a basis for calculating percentile curves the cumulative frequency distribution should be preferred, rather than assuming a normal distribution, since fetal diseases or developmental anomalies result in an uneven distribution with an over-representation of small for date fetuses. The selection of data for calculating normal values must be rejected because of the arbitrary decisions which this entails.

Anthropometry↗
PubMed1991

[Gestational age related correction of birth weight by parity. Body height and weight of the mother].

Corrections to the real birthweight of infants are proposed from the 28th to 42nd week of pregnancy. These take account of the influence of parity and maternal height and weight. The effect of these three characteristics on the birthweight is calculated both one and two dimensionally by combining the characteristics with the actual duration of pregnancy. Thus, for example, after 40 full weeks of pregnancy 560g of the birthweight would be considered the weight correction. For newborn infants of relatively short light-weight mothers, this account should be added to the real birthweight ascertained, and for the babies of relatively tall, heavy mothers it would be subtracted. Only after this correction can the two dimensional classification of neonates into hypotrophic, eutrophic or hypertrophic take place according to birthweight and duration of gestation.

Adult↗
PubMed1990

[Recommendations for the diagnosis and therapy of meningitis, Waterhouse-Friderichsen syndrome and encephalitis in childhood].

Representatives of the working group of "Neuropaediatrics" and "Infectology" like to present recommendations on diagnostics and treatment of infectious diseases on the CNS. Individual opinions can not be considered in recommendations always. Therefore we have to understand these recommendations in this way that individual decisions will not be restricted in special situations.

Child↗
PubMed1990

Measuring the impedance of erythrocytes in patients with cystic fibrosis.

A study of the dielectric properties of fresh, washed erythrocytes from three groups of 13 children, one with cystic fibrosis, and one each of healthy children of comparable age and comparable weight, was conducted after resuspension in their own plasma or in sodium phosphate buffer. The erythrocytes of the patients with cystic fibrosis showed significant variations in impedance, especially compared to the control group of comparable age. Further studies are required to ascertain whether these results are of diagnostic significance.

Child↗
PubMed1979

[Follow-up studies of high-risk children at the time of entering school in comparison with a normal group].

Somatic, neurological and psychological follow-up examinations performed on 54 high-risk children for school enrollment gave no significant differences in comparison with a randomized equal number of normal control children, with regard to physical development and maturation as indicated by carporadiograms. So far as neurological development was concerned, there was a slightly more frequent occurrence of minimal defects and, anamnestically, a marked retardation in the mastering of static functions (running) and speech development in the high-risk group. The results were in correlation with the psychological test findings. Here, too, a more frequent occurrence of impaired intellectual functions was found, which led to a greater number of deferments, conditional enrollments and transfers to special schools. Prospective examinations afford better opportunities of etiologically classifying and registering defects, including light forms. In this connection problems of screening are also discussed.

Brain Damage, Chronic↗
PubMed1978

[Determination of residual bilirubin binding capacity in the serum of newborn infants using bromphenol blue].

In serum specimens collected from premature infants the residual bilirubin binding capacity was determined by a direct spectrometric method using bromphenol blue. The bindingin capacity determined in this way is strongly correlated to the serum bilirubin level. Changes in binding capacity are shown during the first 16 days of life. Experiments on model sera show the dependence of binding capacity for bromphenol blue on the ratio albumin/bilirubin. The results are discussed with respect to the urgency of blood exchange transfusions preventing danger of kernicterus.

Bilirubin↗
PubMed1978

[Hydrocephalus].

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Child↗