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Biomedical subjects

K J Cho

Publications and source records attributed to K J Cho.

At least 163 records · Page 9Linked to original sources

Angiographic findings in renal amyloidosis.

The renal angiographic and venographic findings in five patients with renal amyloidosis are described. The findings include (1) normal or slightly decreased main renal artery; (2) pruning, tortuosity, and irregularity of the distal interlobar arteries, associated with smooth cortical margin and relatively homogeneous nephrogram; (3) nonvisualization of interlobular arteries; (4) asymmetric and uneven involvement of the kidneys; (5) prominent extrarenal arteries; and (6) renal vein thrombosis, frequently involving segmental and interlobar veins. Angiographic differential points between renal amyloidosis and other chronic renal parenchymal diseases are discussed with emphasis on the clinical history.

Aged↗

Angiography of pancreatic arteriovenuos malformation.

Three cases of pancreatic arteriovenous malformation are presented. This entity is known to be a part of Osler-Weber-Rendu disease. However, asymptomatic pancreatic arteriovenous malformation also occurs. The angiographic features are specific and consistent of dilated and tortuous feeding arteries, racemose intrapancreatic vascular network, and early filling veins. Massive gastrointestinal hemorrhage is a frequent complication. The importance of preoperative localization of the lesion and postoperative confirmation of complete resection by angiography is stressed.

Arteriovenous Malformations↗

Gastric antral diaphragm.

Roentgenographic abnormalities in 3 patients with antral diaphragm are presented. Barium studies revealed the diaphragm as a persistent, circumferential defect in the distal antrum, often associated with peptic ulcers or gastric outlet obstruction. At endoscopy the central aperture does not change during peristalsis in contrast to the pylorus, which does. Since the lesion can be excised, its preoperative demonstration by barium studies and endoscopy is emphasized.

Female↗

Alterations in gastric physiology caused by selective embolization and vasopressin infusion of the left gastric artery.

Alterations in gastric physiology caused by selective embolization and vasopressin infusion of the left gastric artery were evaluated in 29 dogs. Gastric acidity was not significantly altered following Gelfoam embolization but decreased sharply with vasopressin infusion. These results suggest that the segmental occlusion caused by Gelfoam embolization permits significant collateral blood flow to the gastric mucosa, while the arteriolar and capillary constriction caused by vasopressin effectively decreases mucosal blood flow. These findings are consistent with the clincal observation that embolization is more effective in controlling bleeding ulcers, while vasopressin infusion is more effective for controlling hemorrhagic gastritis.

Angiography↗

Embolic control of hypertension caused by segmental renal artery stenosis.

Renovascular hypertension was controlled in a 15-year-old boy by total infarction of the renal parenchyma behind a segmental renal artery stenosis. Two separate embolizations were required to occlude the branches distal to the stenosis. Blood pressure did not return to normal until after the second procedure. This approach may be useful in patients with intrarenal arterial stenoses who would be difficult to approach operatively without sacrificing a significant portion of the kidney.

Adolescent↗

Effects of experimental hepatic artery embolization on hepatic function.

The hepatic artery was embolized with Gelfoam in 12 dogs to evaluate the effect of embolization on hepatic function. Liver function studies, including SGPT, alkaline phosphatase, BSP test, and bilirubin, were done serially over a 6 week period following the embolization. Eleven of the 12 embolized dogs survived the 6 week experimental period. Hepatic artery embolization caused some liver damage; however, recovery occurred by 6 weeks. These results suggest a possible therapeutic role for hepatic artery embolization in patients with massive hepatic bleeding or hemobilia who are not surgical candidates and who would require hepatic lobectomy or dearterialization to control the bleeding.

Animals↗

Angiographic and ultrasonic findings in infected simple cysts of the kidney.

This paper describes angiographic and ultrasonic findings in three patients with proven infected renal cyst. The clinical picture was that of inflammatory renal disease. B-mode ultrasonography showed the characteristic features of renal cyst; however, this technique cannot differentiate between infected and simple cysts. Selective renal angiography demonstrated the following, enabling differentiation from simple renal cyst; hypervascular rim, irregular inflammatory vessels, indistinct interface between cyst and adjacent parenchyma, and prominent capsular branches. Since percutaneous puncture of an infected renal cyst or abscess carries risk of infectious complications, angiography appears justified only for those patients with fever and flank pain who have cystic lesions in the kidney confirmed by echography.

Adult↗

Angiographic assessment of pancreatic pseudocyst: a reappraisal.

The correct diagnosis was established by angiography in 16 of 21 patients with pancreatic pseudocyst. The characteristic angiographic abnormalities are arcuate stretching of intrapancreatic arteries combined with a filling defect in the parenchymal phase of the angiogram. In the five false negative patients, the diagnosis was not made either because of the small size of the pseudocyst or a primary extrapancreatic location of the lesion. Because of this high false negative rate and the accuracy of B-mode ultrasonic scanning in abdominal cystic lesions, ultrasound should be the primary diagnostic modality in patients with suspected pancreatic pseudocysts.

Angiography↗

Prostaglandin E1 as a pharmacoangiographic agent for arterial portography.

The effects of increasing single selective doses of prostaglandin E1 (PGE1) on superior mesenteric arterial flow and portal and systemic blood pressures were studied in dogs to assess its value as a vasodilatory agent for pharmacoangiography. PGE1 consistently increased blood flow, with an average increase of 187%, but had minimal effect on portal and systemic blood pressure. 25 mug of PGE1 gave an ideal flow curve for pharmacoangiography, with a maximum effect 30 seconds after injection.

Angiography↗

The columnar epithelial-lined lower esophagus and its association with adenocarcinoma of the esophagus.

Four cases of columnar epithelial-lined lower esophagus are presented. The condition can be complicated by esophagitis, ulceration, perforation, and adenocarcinoma of the esophagus. When the squamocolumnar junction is involved by peptic esophagitis, the area of mucosal transition appears as a tapered, strictured segment or a ring-line constriction some distance proximal to the muscular esophagogastric junction. Hiatal incompetence with massive gastroesophageal reflux was evident in 1 case. A deep penetrating ulcer may occur anywhere along the columnar epithelium, identical to peptic gastric ulceration. The columnar-lined lower esophagus should probably be considered a premalignant condition. Two of these patients had associated esophageal adenocarcinoma.

Adenocarcinoma↗

Transcatheter embolization of the marginal artery of Drummond as treatment for life-threatening retroperitoneal hemorrhage complicating heparin therapy.

We report a case in which life-threatening retroperitoneal hemorrhage complicated heparin therapy. The bleeding originated from the marginal artery of Drummond which was catheterized with a 3-Fr coaxial catheter system (Tracker-18 catheter) and embolized with microcoils. Bleeding stopped and no ischemic complications developed for 3 years after embolization.

Angiography, Digital Subtraction↗

Radiological prediction of the depth of invasion and histologic type in early gastric cancer.

In cases of early gastric cancer (EGC), the depth of tumor invasion and histologic type are important factors in its prognosis. To predict the depth of invasion and histologic type by a double-contrast barium study of the stomach, 304 consecutive patients with EGC were analyzed, comparing barium study with pathologic findings. We predicted the depth of invasion and histologic type according to the lesion size, surface pattern, and surrounding mucosal pattern. The depth of tumor invasion was correctly diagnosed in 65.3% (66 of 101) of cancers limited to the mucosal layer (m), and in 59.1% (110 of 186) of cancers which have invaded to the submucosal layer (sm). The histologic type was correctly predicted in 78.9% (56 of 71) of a differentiated adenocarcinoma, and 73.1% (57 of 78) of an undifferentiated adenocarcinoma. Prediction of the depth of tumor invasion and histologic type was promising and showed good correlation to the pathologic findings.

Adenocarcinoma↗