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Biomedical subjects

K J Awan

Publications and source records attributed to K J Awan.

At least 37 records · Page 2Linked to original sources
PubMed1978

Intraepithelial epithelioma (Bowen's disease) of conjunctiva and chronic lymphocytic leukemia.

Occurrence of intraepithelial epithelioma (Bowen's disease) of the conjunctiva in a 54-year-old white man with chronic lymphocytic leukemia and bilateral labiopalatine clefting is discussed. The lesion developed slowly during 3 years following mechanical trauma to the eye. The interrelationship between trauma, Bowen's disease, and chronic lymphocytic leukemia remains obscure. It is postulated that an altered immunologic status might be responsible for neoplastic changes in the posttraumatic healing process. Intractable lesions in a patient with abnormal immunologic system or with an already proven malignancy should be studied by excisional biopsy.

Bowen's Disease↗
PubMed1977

Arterial vascular anomalies of the retina.

The incidence of nonaneurysmal congenital anomalies of the retinal arteries was determined by ophthalmoscopic examination of the eyes of 2,100 consecutive healthy individuals whose ages ranged from 6 to 68 years. Unusual anomalies were triple branching, anomalous course, arteriolar-arterial crossing, unusual tortuosity, prepapillary loops, aberrant macular arteries, unusual supply of the optic disc, presumed total ciliary arterial supply of the retina, anomalous relationship with the central retinal vein at the optic disc, and pseudoaneurysm of a major retinal artery. Cilioretinal arteries are the commonest of the congenital vascular anomalies of the retina.

Adolescent↗
PubMed1977

Familial polyposis and angioid streaks in the ocular fundus.

A 48-year-old white man had angioid streaks associated with familial polyposis. Although the streaks were seen only in the right eye when examined by ophthalmoscopy, a tiny angioid streak was also discovered in the apparently uninvolved left eye during fluorescein angiography.

Angioid Streaks↗
PubMed1977

Cryotherapy in phthiriasis palpebrarum.

A 5-year-old white girl had phthiriasis palpebrarum of both upper eyelids. Excellent cooperation by the patient permitted the destruction of adult lice and the nits by cryoapplication under the slit lamp. Cryotherapy seems to be a promising method of treating phthiriasis palpebrarum in a single office visit.

Child, Preschool↗
PubMed1977

Microhyphema.

A case of microscopic hemorrhage into the anterior chamber is described. Slit-lamp examination disclosed a steady fine stream of blood issuing from a tiny grayish bulblike microhemangioma at the pupillary border. Fluorescein biomicroscopy revealed several similar microhemangiomas on the borders of each pupil. It is presumed that minor ocular irritation, due either to poison ivy or to a menthol (0.70%) cream which the patient applied to her face, precipitated the microhyphema.

Adult↗
PubMed1977

Association of ocular, cervical, and cardiac malformations.

Association of ocular, cervical, and cardiac anomalies is discussed. A case with severe congenital heart disease, unusual Duane's retraction syndrome, classified here as atypical typical, and Klippel-Feil anomaly is described. To alert the physicians to such an association of congenital malformations and for nosological purposes this entity may be called oculo-cervico-cardiac syndrome. Importance of the association of heart and eye abnormalities is stressed and syndromes with associated ocular and cardiac anomalies are briefly discussed.

Abnormalities, Multiple↗
PubMed1977

Sebaceous carcinoma of the eyelid.

An unusual case of sebaceous carcinoma of the eyelid is described. Site of the lesion and noninvolvement of the lid margin or the skin suggest that it arose from meibomian glands. A complete excision and not partial biopsy of the suspected lesions is advised for histopathologic studies. It is suggested also that the specimen must be examined by an ophthalmic pathologist.

Adult↗
PubMed1977

Hypotelorism and optic disc anomalies: an ignored ocular syndrome.

Hypotelorism, decreased interpupillary or interocular distance, deserves a wider recognition. Its association with anomalies of the optic disc is emphasized. This association appears to be a well defined ocular syndrome and may be considered another helpful clue in the differential diagnosis of the so-called pseudopapilledema from true papilledema.

Abnormalities, Multiple↗
PubMed1977

Shrinkage of conjunctiva, Terrien's marginal degeneration, and perforation of cornea in rheumatoid arthritis.

The unusual occurrence of severe conjunctival shrinkage resembling ocular pemphigoid and bilateral Terrien's marginal degeneration of the cornea in rheumatoid arthritis is described. In less than two years the right eye was lost due to spontaneous corneal perforation and the left became totally blind because of scarring and shrinkage of the conjunctiva. A common unknown factor is speculated as an etiologic relationship between rheumatoid arthritis, ocular pemphigoid, and Terrien's marginal corneal degeneration.

Aged↗
PubMed1976

Marcus gunn (jaw-winking) syndrome.

Association of Marcus Gunn (jaw-winking) syndrome with ipsilateral familial cleft lip occurred in a 17-year-old white boy. He had anisometropia and esotropia with amblyopia of the involved eye. Jaw-winking and blepharoptosis improved to a cosmetically acceptable extent as the child grew older.

Adolescent↗
PubMed1976

Mikulicz's disease and Mikulicz's syndrome.

The pathogenesis, clinical manifestations, and historical development of Mikulicz's disease and Mikulicz's syndrome are given. It is recommended that the term "Mikulicz's syndrome" be dropped to avoid confusion with the rare and well defined entity "Mikulicz's disease."

Diagnosis, Differential↗
PubMed1976

Strabismus fixus divergens and associated craniofacial anomalies.

A case of congenital strabismus fixus divergens is described. Other anomalies were vertically oval corneas, high mixed astigmatism, amblyopia, horizontal nystagmus, microcephaly, maxillary hypoplasia, micrognathia, low set large ears, and hyperostosis frontalis interna.

Exotropia↗
PubMed1976

Adverse systemic reactions of topical cyclopentolate hydrochloride.

Systemic toxic effects of 2% cyclopentolate eye drops were studied in 66 adults. Out of these, 10 developed systemic toxic reactions. In 6 cases it was mild and in the remaining 4 cases the severity was moderate. Recovery was complete without any treatment. It is suggested that the use of 2% cyclopentolate drops should be restricted, and weaker concentrations applied with caution.

Administration, Topical↗
PubMed1976

Presumed glial retinal hamartomas in Usher's syndrome.

The presence of glial hamartomas of the retina and the optic disc in retinitis pigmentosa is discussed. This association is described in a 26 year old white male with Usher's syndrome who had at the posterior pole of each eye a mass which closely resembled the mulberry-like lesions of tuberose sclerosis. Several fine blood vessels were seen on the surface of these masses. The significance of the association of these presumed hamartomas with retinitis pigmentosa is not clear. They might be the result of a focal reactive hyperplasia of the glial cells of the retina.

Adult↗
PubMed1976

Systemic toxicity of cyclopentolate hydrochloride in adults following topical ocular instillation.

A case reported of a 27-year-old white woman who developed systemic toxicity after the local instillation of one drop of 2% cyclopentolate solution in each eye. The usefulness and toxic reactions of this very valuable drug are discussed. It is recommended that every ophthalmologist should warn not only the parents of the children, but also the adult patients about the possibility of systemic reaction before this drug is used and where possible the lowest concentration of solution be used. It is also suggested that a sufficient amount of injectable physostigmine salicylate be kept handy in the office emergency kit.

Adult↗