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Biomedical subjects

K Iwaki

Publications and source records attributed to K Iwaki.

83 records · Page 5Linked to original sources
PubMed1980

Recurrence of intracranial meningiomas, with special reference to radiotherapy.

Three hundred thirty-six cases of meningioma were analyzed retrospectively with regard to the recurrence rate and the effect of radiotherapy on recurrent meningiomas. There was recurrence in 14 out of 173 cases (8.1%) after apparently complete removal and in 26 out of 90 cases (28.9%) after obviously incomplete removal. Radiotherapy was given in 7 cases after repeat complete removal of recurrent tumors. It was concluded that irradiation in recurrent menigiomas is of little value, although it might be beneficial occasionally. One of the most important limiting factors in application of radiation therapy to recurrent meningiomas appears to be vulnerability to radiation of the surroundng brain, which has been damaged already.

Adolescent↗
PubMed1979

Changes in serum succinyltrialanine p-nitroanilide hydrolysing activity in hepatobiliary diseases.

Serum succinyltrialanine p-nitroanilide hydrolysing activity was elevated in patients with hepatobiliary diseases. The highest activities were seen in acute cholangitis and intrahepatic cholestasis. The change in succinyltrialanine p-nitroanilide hydrolysing activity was closely associated with those in gamma-glutamyltranspeptidase and alkaline phosphatase activities. In some cases, however, the former was more sensitive than the latter.

Adult↗
PubMed1979

[Cerebrospinal fluid (CSF) cytology using "cytospin" in patients with brain tumors (author's transl)].

Cerebrospinal fluid (CSF) cytology was performed using cytocentrifugation method ("Cytospin") in 88 preoperative patients who had been known to have deeply seated brain tumors by CT. 20 cases (22.7%) among them showed positive findings and 11 cases (12.5%) probably positive findings. High incidence of positive results were obtained in germinomas (60.9%), ependymomas (50.0%), medulloblastomas (40.0%), followed by malignant lymphomas (20.0%), pontine gliomas (16.7%) and metastatic tumors (16.7%). In contrast, it was persistently negative in cerebral astrocytomas, glioblastomas, teratomas, epidermoids, meningiomas and neurinomas. This method was quickly prepared in 30 minutes and was superior in retaining detailed cytomorphology. It was concluded that the CSF cytology is a less invasive diagnostic investigation, can provide an additional information as regards the nature of some kinds of brain tumors and is still useful even in the CT era.

Adolescent↗
PubMed1978

Redundant nerve roots of the cauda equina.

Two cases of redundant nerve roots syndrome are presented. Both cases displayed coiled and elongated nerve roots of cauda equina, associated with proliferated fibrous tissue on the ligamentum flavum or with spondylosis and disc protrusion compressing the caudal dural sac. The pathogenesis of the syndrome of redundant nerve roots is briefly discussed.

Adult↗
PubMed1978

[The superior facet syndrome--report of three cases and a review of the literature (author's transl)].

Within the past 6 months we paid special attention to the superior facet syndrome on examining the patients with lumbar pain at the outpatient clinic. Out of 264 patients who complained of lumbago or sciatica, this syndrome was suspected in three patients and verified in all of them by operation. Neurologically it was difficult to differentiate this syndrome from disc protrusion or other related conditions. On the other hand, plain roentgenographic examinations were valuable: horizontal portion of the superior facet was larger and thicker than normal so that the a-p view of the lumbar spine showed a large bulbous processes joining in the frontal plane, and a narrowing of the interlaminal spaces was seen in some case. A differential diagnosis between this syndrome and the major type of lumbar canal stenosis can be made by means of dynamic myelography. Although the myelography with watersoluble contrast medium reveals nerve roots better than Myodil myelography, identification of the nerve roots at the lateral recesses is not necessarily easy, and the final diagnosis has to be made at operation.

Adult↗
PubMedDate not supplied

Prevention of azoxymethane-induced intestinal tumors by a crude ethyl acetate-extract and tryptanthrin extracted from Polygonum tinctorium Lour.

The effect of a crude ethyl acetate (AcOEt)-extract and tryptanthrin extracted from the Indigo plant (Polygonum tinctorium Lour.) on azoxymethane (AOM)-induced intestinal tumors was examined in F344 rats. The rats were given subcutaneous (s.c.) injections of either AOM (15 mg/kg body weight (b.w.)) once a week for 3 weeks to induce atypical crypt foci (ACF) as a known cancer precursor, or AOM (7.5 mg/kg b.w.) once a week for 10 weeks to induce intestinal tumors. The rats were also administered the AcOEt-extract (500 mg/kg b.w.) or tryptanthrin (50 mg/kg b.w.) orally, 5 days a week, for 7 or 30 weeks, starting two days before the first administration of AOM. All rats were killed 4 or 20 weeks after the last treatment. In the short-term experiment, the incidence of ACE and atypical crypts (AC) in the groups receiving the AcOEt-extract and tryptanthrin was significantly lower than in the control group. In the tumor-inducing experiment, intestinal tumor incidence in the tryptanthrin group was lower than in the AOM-control group (5% versus 26%), and small intestine tumor incidence in the AcOEt-extract and tryptanthrin groups were lower than in the AOM-control group (0% and 0% versus 23%). These results show that the AcOEt-extract of Indigo and tryptanthrin have cancer chemopreventive activity.

Acetates↗