Search PubMed⌕ Search

Biomedical subjects

K Ishimatsu

Publications and source records attributed to K Ishimatsu.

12 recordsLinked to original sources

[Leakage radiations in a medical electron accelerator facility--calculation of neutron doses in the facility].

Neutron doses often come dominant in mazes of electron accelerator facilities in which X-rays of energies more than 10 MV are produced. A simple analytical method to calculate neutron doses in such a facility is developed. In the calculation procedure, it is assumed that the irradiation room is spherical in shape and the maze is cylindrical. Multiple reflection of neutrons is also considered using the albedo concept in the calculation. The procedure allows to exist a hanging wall over the entrance of the irradiation room and also multiple legs in the maze. All the parameters used in the calculation are given definitely in the procedure, and any experiment is unnecessary to determine value of the parameters. Comparison of the calculated results with experimental ones will be described in the following report.

Hospital Departments↗

[Leakage radiations in a medical electron accelerator facility--measurement of neutrons and comparison with calculation].

Neutron dose equivalent rates are measured in the irradiation room and the maze of a medical electron accelerator facility. An m-counter used for measurement is associated with a gate circuit to reject piled up signals caused by pulsed X-rays, so that it is possible to measure the neutrons without obstruction by the piled up signals even in the irradiation room. Counting loss of neutrons is mathematically corrected, and the correction factor comes nearly equal to 1.5 at dose points close to the entrance to the irradiation room when 14 MV X-rays are generated. The measurement in the maze agrees with the calculation reported in the preceding report in a factor less than 1.5 except for dose points close to the entrance to the irradiation room.

Hospital Departments↗

[Leakage radiations in a medical electron accelerator facility--X-rays and capture gamma-rays].

Absorbed dose rates of photons are measured in the maze of a medical electron accelerator facility. Radiations in the maze include high energy recoiled electrons other than low energy reflected X-rays. An ionization chamber for low energy X-rays is used for measurement, and is put in a build-up cap thick enough to obstruct the recoiled electrons of which contribution to the chamber output comes sometimes equal to that of X-rays. Dose rates of capture gamma-rays in the maze are estimated applying the calculation of neutron dose equivalent rates reported in the preceding paper. It is proved that capture gamma-rays are dominant in the dose rates measured in the maze at 14 MV X-ray generation. The estimated absorbed dose rates of total photons including capture gamma-rays and reflected X-rays agree with the measured ones in the range from +10% to -27%.

Electrons↗

[Leakage neutrons and X-rays in a therapeutic microtron facility].

Measurements of dose equivalent rate distribution in a medical microtron facility were done for neutrons and X-rays originated from 14 MV or 8 MV X-ray irradiation by the microtron. Measured data are described with empirical formulas for convenience of quantitative reconstruction of the data. A formula consisting of a simple power function agrees well with measured data except for thermal neutrons, and is understood to describe the dose rate separating into the scattered and unscattered components in the case of the point source. The thermal neutron distribution in the maze is described with another formula of an exponential function. A discrepancy was observed between the X-ray distribution in the maze from 14 MV X-ray irradiation and that from 8 MV irradiation. This is estimated to be caused by a contribution of capture gamma-rays increasingly emitted in the case of 14 MV X-ray irradiation.

Neutrons↗

[Measurement of neutrons from an electron accelerator by rem-counter].

In the measurement of neutrons from the medical electron accelerator by a rem counter, two problems disturb accurate measurements. One is the pile-up of signals produced by X-rays during each X-ray burst and the other is the increased counting loss caused by bunched nature of yielded neutrons. The time spectrum of neutrons measured by the rem counter 2202 D (manufactured by Studsvik) rises up to a maximum value by about 20 microseconds and then falls down exponentially with a time constant of about 90 microseconds. On the other hand, that of X-rays is roughly rectangular with several microseconds width. A time discriminating system was prepared to be combined with the rem counter, which was triggered by leading edge of electron beam pulses, rejected pile-up signals due to X-ray bursts, and counted pulses of neutrons in a specified time window. The system discriminated the pile-up enough to measure neutrons at a X-ray dose rate of at least 30 mGy/h. Nonparalyzable counting loss correction was practicable upto about 10 mSv/h for the beam pulse rate of 85 Hz, in which the dead time of the rem counter was estimated as 4 microseconds.

Neutrons↗

Production system for 18F-2-deoxy-2-fluoro-D-glucose--a trial for automatic production.

We have developed a production system for 18F-2-deoxy-2-fluoro-D-glucose (18F-2FDG), which assures reliable production with easy handling and reduces radiation exposures to the operator. Chemical procedures in this system are the same as manual method developed in NIRS. This system has 2 operation modes; one is remote controlled manual operation mode and the other is microcomputer controlled automatic operation mode. In remote controlled mode, we tested this system 5 times and 18F-2FDG synthesized was supplied for clinical use once. The mean radiochemical yield of 18F-2FDG from the target gas recovery with decay time correction was 8%, that is the same as in the manual synthesis. It took about 2 hours from end of bombardment (EOB) to end of synthesis (EOS). Since this time is shorter than in manual synthesis, the available activity at EOS is increased.

Deoxy Sugars↗