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Biomedical subjects

K I Myshkin

Publications and source records attributed to K I Myshkin.

121 records · Page 7Linked to original sources
PubMedDate not supplied

[Mathematical methods in the diagnosis of the thyroid gland function].

At present effective diagnosis of deviations from euthyroidism in diseases of the thyroid gland presents certain difficulties. The most rational direction in the solution of this problem is introduction of quantitative methods into the diagnosis. Symptoms encountered in case histories of 1500 patients with goiter transformation were coded for this purpose according to the chosen algorhythm. Only those symptoms which were present in all the case histories were selected for this study. The data obtained were treated on "Ypapi-2" computer. A table in which every sign of the disease had a quantitative expression was drawn on the basis of the results. Diagnosis according to the mentioned mathematical table is more effective, and, besides, there is no subjectivism in the diagnosis.

Diagnosis, Computer-Assisted↗
PubMedDate not supplied

[Main principles of the treatment of surgical patients with concomitant diabetes mellitus].

A total of 955 surgical patients with concomitant diabetes mellitus were treated at the Stomatological Medical Institute Surgery Faculty Hospital. Therapeutic experience made physicians arrive at a conclusion on the necessity of active detection of carbohydrate metabolic derangements in high risk patients, as well as reasons for the decompensation of diabetes mellitus in surgical patients. Decompensation was caused by the activation of the hypothalamohypophyseal-adrenal system in stress and a considerable increase in contrainsular factors in the blood with a decrease in adaptive function of the pancreas. A high proteolytic activity of the blood in decompensated diabetes mellitus resulted in insulin inactivation. Means for the correction of the above disorders were proposed.

Blood Glucose↗
PubMedDate not supplied

[Diagnosis of hypothyroidism with the use of a differential-diagnosis mathematical table].

The function of insular apparatus beta-cells and individual components of the contrainsular system were studied in 53 young patients with insulin-dependent diabetes mellitus. It was shown that early stages of the disease, including potential diabetes mellitus, are characterized by hyperinsulinemia, associated with an increased adrenocortical glucocorticoid function. Relative insulin insufficiency develops as diabetes progresses (subclinical stage of the disease) in the presence of persisting hyperinsulinemia and increasing aldosteronemia. An intensified adrenocortical function appears to be of an adaptive character at the preclinical stages of the disease. The concept of hormonal dissimilarity of the known forms of diabetes mellitus is documented with reference to the insulin-dependent forms in young subjects.

Adolescent↗
PubMedDate not supplied

[Oxygen metabolism (based on polarographic data) in patients with thyroid diseases].

The results are presented of the studies of oxygen metabolism in the muscular tissue of patients with the thyroid goiter formation. An original method of the polarographic study allows one to observe the process of oxygen transport not only from the intracellular space into the cell, but also from the blood channel into the intracellular space. Oxygen utilization curve was recorded after prolonged ischemia (15 minutes) the oxygen recovery curve was noted, according to which the oxygen recovery rate coefficient, allowing to judge the circulation time and the vascular wall permeability, was counted by analogy with oxygen utilization rate determination. The ratio of these coefficients was used as an index for the tissue supplying with oxygen. The data are presented of studying 105 patients with different forms of the thyroid goiter formation. The informativeness of the utilization rate coefficient is examined for evaluating oxygen consumption by tissues. This index was practically equal in patients with diffuse toxic goiter, nodose euthyroid goiter and in the controls. At the same time the coefficient of oxygen recovery rate and the coefficient ratio of oxygen recovery and utilization rates were significantly elevated in patients with diffuse toxic goiter (1.3 +/- 0.21, 4.33 +/- 0.76) in comparison with the patients suffering from nodose euthyroid goiter (0.72 +/- 0.2, 2,95 +/- 0.66) and the controls (0.67 +/- 0.18, 1.8 +/- 0.37). In the patients with diffuse toxic goiter these indices returned to normal (0.44 +/- 0.11, 1.57 +/- 0.63) following the preoperative preparation.

Biological Transport↗
PubMedDate not supplied

[Trepanobiopsy in the preoperative diagnosis of thyroid diseases].

Data are presented concerning the use of trepanobiopsy in preoperative diagnosis of diseases of the thyroid gland. No complications followed 188 trepanobiopsies; clinical diagnosis was changed after trepanobiopsies in 60 patients. Indications to trepanobiopsy in enlargement of the thyroid gland were worked out.

Adenoma↗