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Biomedical subjects

K I Kim

Publications and source records attributed to K I Kim.

63 records · Page 4Linked to original sources
PubMed1978

Estimation of the fraction of the lactose in a high lactose diet available for fermentation in the cecum and colon of the rat.

Experiments were conducted to determine the amount of lactose which passed into the large intestine and the lactase activity in the small intestine of rats (200 g) fed a control diet or a diet containing 30% lactose. The fraction of lactose consumed in a single 1-hour meal that escaped hydrolysis in the small intestine was estimated by measuring the area under a smooth curve of a plot of lactose:marker ratio in the terminal ileum expressed as a fraction of intake, against the fraction of the total marker that passed into the large intestine. This amounted to approximately 30% and 31.5% of the lactose consumed for the rats fed the control and 30% lactose diets, respectively. In another experiment in which the rats were fed a diet containing 30% lactose and the Cr-EDTA marker ad libitum for 1 week, approximately 43% of the lactose consumed became available for fermentation in the large intestine. This work suggests that a substantial fraction of the lactose ingested is available for fermentation in the large intestine. The lactase activity of homogenates of the small intestine of rats fed the control or high lactose diet was 106 +/- 5 or 115 +/- 4 mg lactose/30 minutes/rat (P less than 0.05), respectively. The lactase activity in the small intestine homogenate (mucosa + contents) was significantly higher than that actually available in vivo (110 +/- 7 versus 69 +/- 4 mg/30 minutes/rat).

Animals↗
PubMedDate not supplied

Pulmonary involvement of idiopathic hypereosinophilic syndrome: CT findings in five patients.

PURPOSE: The aim of this study was to assess the CT findings of pulmonary involvement in patients with idiopathic hypereosinophilic syndrome (HES). METHOD: The study included five patients with idiopathic HES who had pulmonary involvement proven by bronchoalveolar lavage (n = 3) or based on clinical and radiologic findings (n = 2). Four patients had high resolution CT and one had conventional CT. The CT scans were retrospectively reviewed by two chest radiologists for pattern and distribution of disease. RESULTS: All five patients had several small nodules in both lungs at CT scan. Four patients had nodules with a halo of ground-glass attenuation. Three patients had focal areas of ground-glass attenuation in both lungs. These lesions were present in all lung zones and involved mainly the peripheral lung. There was neither lobar predilection nor peribronchovascular distribution. Other organs involved included bone marrow (n = 3), liver (n = 3), stomach (n = 1), and peritoneum (n = 1). CONCLUSION: The CT findings of pulmonary involvement in patients with idiopathic HES included small nodules with or without a halo of ground-glass attenuation and focal areas of ground-glass attenuation mainly in the lung periphery.

Adult↗
PubMedDate not supplied

Carbamate poisoning: high resolution CT and pathologic findings.

Carbamate insecticides are commonly used agricultural insecticides. The major cause of morbidity and mortality in acute carbamate poisoning is respiratory failure associated with pulmonary edema. Although carbamate poisoning is well recognized in the clinical literature, the findings of high resolution CT (HRCT) with carbamate have not been reported. We report the radiographic and HRCT findings of a patient with acute carbamate poisoning who had pathologically proven interstitial pneumonitis after resolution of initial pulmonary edema.

Acute Disease↗
PubMedDate not supplied

Near drowning: thin-section CT findings in six patients.

PURPOSE: The purpose of this study was to assess the thin-section CT findings of near drowning in six patients. METHOD: Thin-section (1 mm collimation) CT scans of six patients who experienced near drowning were retrospectively analyzed. The CT scans were performed 0-5 days (median 1 day) after near drowning. RESULTS: Thin-section CT findings included bilateral patchy or diffuse areas of ground-glass attenuation (n = 6) with geographic pattern (n = 3) and fine intralobular reticular opacities ("crazy-paving" appearance) (n = 3), ill-defined centrilobular nodules (n = 4), and air-space consolidation (n = 1). Distribution of ground-glass attenuation was predominantly central (n = 4) or diffuse (n = 2). Interstitial pulmonary emphysema and pneumomediastinum were present in two patients. CONCLUSION: The thin-section CT findings of near drowning consist of ground-glass opacities with or without associated reticular opacities and centrilobular nodules.

Adolescent↗
PubMedDate not supplied

Imaging of occupational lung disease.

Occupational lung disease comprises a wide variety of disorders caused by the inhalation or ingestion of dust particles or noxious chemicals. These disorders include pneumoconiosis, asbestos-related pleural and parenchymal disease, chemical pneumonitis, occupational infection, hypersensitivity pneumonitis, and organic dust toxic syndrome. Most of these disorders produce diffuse lung disease. Although many of the disorders can be detected at chest radiography, high-resolution computed tomography (CT) has been shown to be superior to chest radiography in depicting parenchymal, airway, and pleural abnormalities. Some occupational lung diseases have characteristic radiologic features suggesting the correct diagnosis, whereas in others, a combination of clinical features, related occupational history, radiologic findings, and literature supporting an association between the exposure and the disease process is required for diagnosis. With advances in chest radiology, including high-resolution CT, radiologists play a key role in the clinical evaluation of occupational lung diseases and should continue their involvement in the diagnosis and treatment of these diseases.

Asbestosis↗
PubMedDate not supplied

Congenital deficiency of the femur.

A classification system for congenital deficiency of the femur is introduced, based on initial radiographic appearance of the hip joint in 60 patients (70 affected limbs). Follow-up records ranging from 1 to 30 years demonstrated a relatively constant percentage of shortening in each patient with further growth (2.4% average change). Treatment programs have been established for each of the following groups: I, short femur with good hip joint (19 limbs); II, short femur and coxa vara (17 limbs); III, short femur with proximal deficiency, a well-developed hip joint, and broad angulated and sclerosed diaphysis (15 limbs); IV, dysplastic distal femoral segment with no hip joint (16 limbs); and V, total absence of the femur (3 limbs).

Acetabulum↗