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Biomedical subjects

K Holubar

Publications and source records attributed to K Holubar.

At least 127 records · Page 7Linked to original sources

Etretinate in the treatment of disseminated porokeratosis of Mibelli.

A 30-year-old man with disseminated porokeratosis of Mibelli (DPKM) was treated with oral etretinate. The dose ranged between 75 mg/day and 50 mg/day for 21 weeks. An improvement of the lesions was observed, especially of very painful verrucous plaques of the left shin. No serious side effect was seen. The patient, who had been incapacitated, is now able to work. The benefit of long-term therapy of etretinate should be considered against its side effects.

Adult↗

Joseph Plenck (1735-1807). A forerunner of modern European dermatology.

A short biography of Joseph (von) Plenck (1735-1807) is presented on the occasion of the 175th anniversary of his death on Aug. 24, 1982. Key data were hitherto unknown or unverified and appear photodocumented here for the first time. Plenck's importance for the historical development of the systematization of skin diseases is stressed.

Austria↗

[The concept of Job syndrome].

The so-called Job's syndrome belongs to the group of diseases designated "chronic granulomatous disease", characterized by recurrent suppurative infections of the skin, eczema, nail dystrophy, conjunctivitis, lymphadenitis and pulmonary infections. Leucocyte function is defective; the nature of the defect has not yet been elucidated. High immunoglobulin E levels are characteristic. The historical background to this syndrome is outlined.

Child↗