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Biomedical subjects

K Hersle

Publications and source records attributed to K Hersle.

At least 37 records · Page 2Linked to original sources

Uses of dextranomer absorbent pads after cryosurgery of cutaneous malignancies.

Secretion from wounds after cryosurgery of cutaneous malignancies may be excessive and may constitute a problem in management. It was found possible to collect and quantitate such discharges by use of highly hydrophilic dextranomer beads (Debrisan). They were applied in convenient, small "tea-bag" pads. The amount and duration of postoperative oozing was approximately proportional to the sizes of the lesions and more impressive in sites of sparse subcutaneous tissue. The absorbent pads also proved to be effective and safe for use as postoperative dressings.

Bandages↗

Once daily application of diflorasone diacetate ointment compared with betamethasone valerate ointment twice daily in patients with eczematous dermatoses.

The clinical efficacy of 0.05% diflorasone diacetate applied once daily, for eczematous dermatoses, was compared with the twice daily application of betamethasone valerate. Both agents were supplied as ointments. Sixty patients were randomized to one of the two treatment regimens. The investigators were unaware of the regimen used. Evaluations were made at 1 and at 3 weeks. There were no statistically significant differences in eight parameters studied at any time during the study. No side-effects were reported.

Administration, Topical↗

Basal cell carcinoma in children. Case report.

Clinical and pathoanatomic features of two children with basal cell carcinoma, an extremely uncommon disease in childhood, are reported. Clinically these lesions had a benign appearance, similar to a foreign body granuloma and an intradermal naevus, respectively, but histological examination showed a picture typical of basal cell carcinoma. The tumours were radically treated and no recurrence occurred during an observation time of 12 and 42 months, respectively.

Adolescent↗

Relationship of pityriasis amiantacea to psoriasis. A follow-up study.

46 patients with pityriasis aminantacea have been reexamined with regard to the later development of psoriasis and atopic diseases, and their occurrence in first and second degree relatives. HLA antigens of the A, B and C series were also determined. Earlier suggestions of a close association with psoriasis were not confirmed. An association with atopic diseases could not be established. Occurrence of seborrheic dermatitis seems, however, common in patients with pityriasis amiantacea.

Adolescent↗

Topical tretinoin therapy and oral lichen planus.

The treatment of severe forms of oral lichen planus is still relatively unsatisfactory. In this controlled study, 0.1% tretinoin in an adhesive base was used in 23 patients. Fifteen other control patients were similarly treated with the vehicle alone. In the tretinoin-treated group, 71% of the atrophic-erosive lesions improved while 29% improved from the vehicle (P less than .05). Reticular-plaque lesions improved in 74% from tretinoin and in 15% from the vehicle (P less than .001). Irritation from tretinoin occurs and thorough usage information is mandatory.

Administration, Topical↗

Chronic non-scarring folliculitis of the scalp.

Forty patients with recurrent follicular pustules of the scalp but without obvious necrosis or residual scarring were re-examined (mean 8.3 years after onset of lesions). The most common age at onset was 20-40 years. The sex ratio (M/F) was 3 : 1. Only 7 of 40 patients had concomitant acne vulgaris on the face. All patients still had active, recurring scalp lesions, although 7 out of 40 had had temporary remissions. Post-lesional scarring was not observed. Oral low-dose tetracyclines had a symptomatic effect in 7 of 11 patients. Most of the patients treated topically with steroids and alcoholic lotions experienced little or no effect. Histopathology disclosed a neutrophilic folliculitis. Bacteriological examinations showed only the usual resident microflora of the scalp with P. acnes being the most frequent species. In 3 cases (5 examined pustules), P acnes was isolated from the content of the pustules without being found on the skin surface over the pustule. Chronic non-scarring folliculitis of the scalp probably constitutes a disease entity.

Adolescent↗