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Biomedical subjects

K Herrmann

Publications and source records attributed to K Herrmann.

185 records · Page 11Linked to original sources
PubMedDate not supplied

The equatorial fibronectin band (EFB) on human spermatozoa--a diagnostic help for male fertility?

Spermatozoa were prepared by swim up technique in the same way as for in vitro fertilization of human eggs and incubated with antihuman fibronectin antibodies in the immunofluorescence technique. Fibronectin mediates adhesive interactions between cells. 69 p.c. of spermatozoa with a normal shape and only 17 p.c. of them exhibiting a pathological shape showed a positive fibronectin-fluorescent band on the equatorial segment, called equatorial fibronectin band (EFB). The cryopreservation of semen did not influence the EFB. The significance of EFB for the sperm-oocyte-binding is discussed in connection with the sperm morphology and epididymal function.

Female↗
PubMedDate not supplied

[Quartz--its relevance for dermatology].

Next to oxygen silicium is the most common substance of our environment. It occurs mostly in form of quartz (SiO2). In the past silica was usually mentioned in connection with foreign body granulomas in dermatological papers. Recently relations between occupational silica exposure and several diseases were reported. Silica exposure was related to the development of scleroderma, lupus erythematodes and sarcoidosis. Pathogenetic connections may be due to a stimulating effect on fibroblasts and due to immunmodulating properties of silica.

Dermatitis, Occupational↗
PubMedDate not supplied

[Rheumatoid arthritis in people of advanced age].

The special position occupied by rheumatoid arthritis in people of advanced age was studied by drawing on a sample of 39 patients who had developed the disease at the age of sixty and over. In the majority of patients the disease was of acute and monoarticular onset, and the pattern of involvement was more often asymmetrical than in younger patients. In three patients the disease followed a fulminant course. The radiological differential diagnosis was complicated primarily by underlying osteoporosis and concomittant degenerative changes. Laboratory tests produced no significant differences compared with the "classic" form of rheumatoid arthritis. Only the percentage of serologically negative patients was slightly increased. Emphasis is put on the difficult differential diagnosis, especially in cases where the onset of the disease is monoarticular.

Adolescent↗