Biomedical subjects

K Heinrich

Publications and source records attributed to K Heinrich.

At least 73 records · Page 4Linked to original sources

PubMed1975

[Ventricular arrhythmias in reduced glycoside tolerance and digitalis poisoning together with myocardial infarct].

Electrophysiological fundamental principles of the heart muscle cell and the conduction system are discussed in detail. Basic differences are described. Pathophysiology of ventricular arrhythmias is emphasized, especially the ectopic conduction development and conduction defect of the reentry mechanism. Decreased digitalis tolerance of different causes and overdosage of digitalis may lead to ventricular premature heart beats and tachycardias. Myocardial infarction is discussed in detail because lethality within the first hours of infarction is mostly caused by ventricular fibrillation.

Arrhythmias, Cardiac↗

PubMed1975

The problem of post-psychotic schizophrenic depressions and their pharmacological induction. Long-term studies with fluspirilene and penfluridol and single-blind trial with fluphenazine-decanoate and flupenthixol-decanoate.

The authors discuss the historical aspects, as well as the various etiological and clinical factors which contribute to the so-called pharmacogenically induced depressions during treatment by means of neuroleptics generally, and long-term neuroleptics especially. An open study on 161 schizophrenic patients treated by means of fluspirilene and 123 patients treated by means of penfluridol is described. A single blind trial on 48 patients, by means of fluphenazine-decanoate and flupenthixol-decanoate, which compares the possible depression-inducing or antidepressant activity of the above drugs, is presented. The criteria for evaluating drug-induced depressions and their two clinical types are discussed.

Adult↗

PubMed1975

[Clinical trial of lofepramine versus imipramine].

Lofepramin is a new derivative of imipramine. Its effects and side effects were compared to those of imipramine in a double-blind trial. 49 hospitalized patients, suffering from endogenous depression, were treated for 20 days with 210 mg lofepramin daily and 52 other patients with 150 mg imipramine daily. The results of the repeated psychiatric examinations were documented using the AMP system. Both substances proved to have high antidepressant effects and showed no significant difference in the quality of their effects.

Acetophenones↗

PubMed1975

[Changes in the psychic factor structure of schizophrenics after release from the hospital].

When studying the "postremission syndrome of exhaustion" in schizophrenics changes in mental factor structures after the patients' discharge from hospital were assessed by performance intelligence scales and check lists of emotional states. Test scores obtained at discharge and 8 weeks afterwards were factor analysed separately. Differences in factor structures of the two matrices represented mainly by independence between emotional and intellectual functions at discharge and negative associations between these factors 8 weeks later could not be completely compensated by similarity rotations of the two factor matrices thus indicating genuine changes in factor structures rather than effects due to methodological procedures.

Adolescent↗

PubMed1974