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Biomedical subjects

K Harries

Publications and source records attributed to K Harries.

8 recordsLinked to original sources

Code Growth, Explicitly Defined Introns, and Alternative Selection Schemes.

Previous work on introns and code growth in genetic programming is expanded on and tested experimentally. Explicitly defined introns are introduced to tree-based representations as an aid to measuring and evaluating intron behavior. Although it is shown that introns do create code growth, they are not its only cause. Removing introns merely decreases the growth rate; it does not eliminate it. By systematically negating various forms of intron behavior, a deeper understanding of the causes of code growth is obtained, leading to the development of a system that keeps unnecessary bloat to a minimum. Alternative selection schemes and recombination operators are examined and improvements demonstrated over the standard selection methods in terms of both performance and parsimony.

Journal Article

Code growth, explicitly defined introns, and alternative selection schemes.

Previous work on introns and code growth in genetic programming is expanded on and tested experimentally. Explicitly defined introns are introduced to tree-based representations as an aid to measuring and evaluating intron behavior. Although it is shown that introns do create code growth, they are not its only cause. Removing introns merely decreases the growth rate; it does not eliminate it. By systematically negating various forms of intron behavior, a deeper understanding of the causes of code growth is obtained, leading to the development of a system that keeps unnecessary bloat to a minimum. Alternative selection schemes and recombination operators are examined and improvements demonstrated over the standard selection methods in terms of both performance and parsimony.

Biological Evolution

Social stress and trauma: synthesis and spatial analysis.

In the last decade violence has emerged as a public health issue, with concomitant interest in surveillance and prevention. This paper is an extension of earlier work seeking to expand the ecological analysis of violence across jurisdictional boundaries, sharpen the level of resolution of such analysis, and ultimately inform small area policy applications in terms of public health initiatives for violence reduction. The underlying model is drawn from stress theory and rests on a set of social indicators representing stress in the Baltimore area. In the earlier work, a set of 24 variables describing violence and socioeconomic conditions across some 1358 areas was factor analyzed and the resulting scores were mapped and interpreted. The present paper takes the analysis a step further in an attempt to identify groups of observations with common traits in order to assist public health professionals and other relevant decision-makers in the process of trauma surveillance, response, and prevention. Cluster analysis was used to combine most similar observations in terms of the three orthogonal factors, and the resulting cluster affiliations were mapped in geographic space. Although no spatial contiguity constraint was put on the clustering algorithm, many statistical clusters were also found to constitute geographic clusters. This implies that the process identified neighborhoods or parts of neighborhoods with shared traits in terms of the underlying set of stressors. Analysis of this type could be used by policy-makers to classify neighborhoods in terms of their needs for various services in addition to public health interventions, including policing, fire protection, building inspection, social work, and education.

Cluster Analysis