Biomedical subjects
K Harami
Publications and source records attributed to K Harami.
Cytologic evaluation of atypical cells in cervicovaginal smears from women with tubal pregnancies.
Cytologic changes in the cervicovaginal smears of 28 women with tubal pregnancies are described. Eleven cervicovaginal smears showed atypical cells, including two cellular patterns: glandular type and naked-nuclei type. About 60% of the cases with atypical cells included the naked-nuclei type of cell, which showed wide variations in nuclear size. Polyploid Feulgen DNA distributions were noted for both types of cells, which probably originate with the Arias-Stella reaction of the endometrium. The cytologic observation of atypical Arias-Stella cells in cervicovaginal smears may be useful in the early diagnosis of ectopic pregnancy, especially if both cell types are present.
The cells from intrauterine contraceptive devices: with special reference to the occurrence of mast cells.
A study of cytologic smears from 26 women using intrauterine contraceptive devices (IUDs) confirmed our previous findings for mast cells and further defined the averages, proportions and types of cells in IUD smears. The average number of cells was found to be 65.5 x 10(4), with a range of 1.3 x 10(4) to 280 x 10(4). The cellular proportions found were 49.0% macrophages, 42.7% polymorphonuclear leukocytes, 4.0% endometrial glandular cells, 1.3% mast cells and 3.0% other cells. Total nucleated-cell counts showed one group with a large number of cells (greater than 5 x 10(5) cells) and another group with a smaller number of cells (less than or equal to 5 x 10(5) cells). These groups showed significant differences in cell types, with a predominance of polymorphonuclear leukocytes in the former and macrophages in the latter. The mast cell counts were similar in both groups. The data suggest that mast cells have a role in IUD functioning. It may be based on an immunologic mechanism.
Cytologic findings in postpartum and postabortal smears.
A study was undertaken to evaluate the cytologic features of pregnancy-induced cell patterns (PIP) observed in postpartum and postabortal cervicovaginal smears. A total of 3,000 PIP were evaluated and studied by an indirect immunofluorescent technique using human chorionic gonadotropin (HCG). Three characteristic types of PIP were demonstrated. In type I PIP, the cells had a sheetlike arrangement with a fine chromatin pattern and were thought to be of decidual origin. Type II PIP were shed in clumps and had round nuclei, cytoplasmic vacuoles and coarse chromatin. They were thought to originate in the endometrium with the Arias-Stella reaction. Type III PIP were large and had large nuclei with marked atypism. They were thought to be cytotrophoblasts. Almost all of the type III PIP were positive with the anti-HCG stain. It is concluded that this classification and analysis is significant and could reduce the number of false-positive cytology reports on postpartum and postabortal smears.
The presence of mast cells in IUD smears. A preliminary report.
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