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Biomedical subjects

K H Emmerich

Publications and source records attributed to K H Emmerich.

32 records · Page 2Linked to original sources
PubMed1991

[Induction of chromosome aberrations in human lymphocytes as a model for evaluating the mutagenic effect of excimer laser irradiation in ophthalmology].

A model for testing the mutagenicity of excimer laser radiation in ophthalmology is presented. In contrast to other studies using cell monolayers, in our study with this model human peripheral lymphocytes (heparinized whole blood) are exposed to laser irradiation at different conditions. The possible mutagenicity of secondary radiation after exposure of the cornea is also considered. The heparinized blood is either injected into the anterior chamber of an enucleated bovine eye or filled into a quartz chamber (positive control). After irradiation the lymphocytes are stimulated and fixed during metaphase, after which the metaphases are scored for chromatid and chromosome aberrations. In the positive control group, exposure to 248 nm excimer laser radiation (500 J, 277 mJ/cm2, 10 and 20 Hz) was followed by a highly significant increase in the yield of chromatid aberrations (chromatid breaks and achromatic lesions).

Animals↗
PubMed1991

[Reasons for failure after episcleral buckling operation of the retina].

In this retrospective study about failures of epiretinal buckling procedures performed over 12 years the causes of failure are analysed. The main ones are: new retinal holes, PVR, wrong localization, and inadequate buckling effect. The aim of this investigation was to find indications of the best technique, with a view to improving the success rate, currently, 80-90%, even further.

Adolescent↗
PubMed1990

[Ear cartilage as tarsus replacement (with long-term results)].

The authors report on 52 lid operations in combination with the transplantation of ear cartilage to serve as tarsus. The preoperative diagnoses were: ectropion (22); entropion (5); tumors (18); lid reconstruction following trauma (7). The long-term results were determined in 24 patients with 29 lids, with an average follow-up time of 26 months. The lid margin fit and the cartilage was palpable in nearly 90% of the long-term results; 83% of the patients were content with the cosmetic outcome.

Cartilage↗
PubMed1990

[Extent and prognosis of eyeball ruptures].

On the basis of 51 ruptures of the globe we present the localization, clinical symptomatology and surgical procedure, as well as the long-term results. The unfavorable prognostic factors are described and compared with these in the literature.

Eye Injuries, Penetrating↗
PubMed1989

[Experimental transvitreal fibrin gluing of the retina].

The authors report on the transvitreal application of fibrin glue in retinal detachment surgery. Methods of application and the course of postoperative resorption are illustrated with reference to experimental studies on rabbit eyes. The prospects for this new method of creating chorioretinal adhesions are pointed out and discussed.

Animals↗
PubMed1986

[Incidence of conjunctival and corneal changes in dialysis patients].

Deposits of calcium salts in the conjunctivas and corneas of 72 patients showed a statistically significant correlation to the duration of hemodialysis. The deposition of calcium salts is not influenced by other signs of disturbed calcium metabolism (Ca-PO4 product, alkalic phosphatase) or the patient's age.

Adult↗
PubMed1985

[Recommendations for the evaluation of complicated aphakia in private accident insurance].

An evaluation of cases in which an expert opinion was obtained during the last 2 years shows that only one-third of patients with traumatic aphakia and a 20/30 loss of vision are adequately assessed. If there are further consequences of the accident (complicated aphakia) they should also be taken into account when assessing loss of vision. A simple method of doing this is described on the basis of three examples.

Adolescent↗
PubMed1984

[Candida albicans endophthalmitis. Results of pars plana vitrectomy without intraocular antimycotic therapy].

An early pars plana vitrectomy was performed without any additional intravitreal antimycotic therapy in 8 eyes of 5 patients with candida endophthalmitis; anatomic healing with a good functional result was obtained. The good prognosis of vitrectomy without intravitreal antimycotic therapy in our patients is seen in (1) a total surgical extraction of the abscess and (2) the better intraocular ventilation obtained for endogenous resistance.

Adult↗
PubMed1981

Malignant tumors after chronic exposure to vinyl chloride.

Correlations between exposure to vinyl chloride and the development of malignant tumors in the liver have been know since 1974 and have been confirmed by many an experimental investigation. Based on the evaluation of mortality statistics from nine different countries an increased incidence of malignant tumors of the lung, the gastrointestinal tract, and the central nervous system (CNS), and of malignant lymphomas is documented in connection with exposure to vinyl chloride. Statistically significant increases, however, are only found in the incidence of malignant liver tumors. Metabolism and toxicology of vinyl chloride are discussed in detail.

Animals↗