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Biomedical subjects

K H Barth

Publications and source records attributed to K H Barth.

At least 91 records · Page 5Linked to original sources
PubMed1979

Early imaging of experimental intestinal infarction with 99mTc-pyrophosphate.

Extensive mucosal small-bowel infarction was produced in 8 dogs by occluding the cranial mesenteric artery. After one hour of reperfusion, 15 mCi (555 MBq) of 99mTc-pyrophosphate was intra-arterially injected into 4 dogs and venously into the other 4. Positive images were obtained in all dogs except 1 which had received an intravenous injection. Diagnostic images were obtained consistently as early as 15 minutes after injection, and the infarcted bowel could still be visualized two hours later. The average tracer content in infarcted small bowel was 0.015% I.D./g. This was about eight times the uptake found in normal dogs. The results show that experimental small-bowel infarction can be detected as early as five hours after the onset of ischemia.

Animals↗
PubMed1978

Abnormalities in the sequence of filling and emptying of mesenteric arteries and veins: a guide to ischemic disease of the bowel.

Functional abnormalities in the sequence of filling and emptying of mesenteric arteries and veins may indicate significant disease of the bowel which is not associated with identifiable structural alterations in the blood vessels. In three patients, focal ischemic damage to the bowel was associated with significantly delayed arterial emptying, delayed or absent filling and emptying of mesenteric veins or a combination of both. Evaluation for sequential filling and emptying of vessels proved most helpful since an abnormal pattern may represent the only angiographic abnormality indicative of intestinal infarction.

Adult↗
PubMed1978

Therapeutic embolization for hemorrhage from locally recurrent cancer of the breast.

Embolization therapy is reported in three patients bleeding from metastatic carcinoma of the breast. Two had life threatening hemorrhage from sternal erosion; internal mammary arteriography indicated encasement, false aneurysm formation or tumor blush. The third patient had intermittent bleeding of extensive fungating axillary and anterior chest wall metastases. Autologous clot alone was used in the first case with immediate cessation of bleeding and transient neurological symptoms secondary to back flow of thrombus into the vertebral artery were noted. The second and third patients received Oxycel-Ivalon and Gel-foam respectively; bleeding ceased and no complications were noted.

Breast Diseases↗
PubMed1978

99mTc-pyrophosphate imaging in experimental mesenteric infarction: relationship of tracer uptake to the degree of ischemic injury.

Four-hour balloon occlusion of the cranial mesenteric artery in 13 dogs produced a spectrum of widespread ischemic injury to the small bowel ranging from superficial mucosal infarction to transmural infarction. Twenty-four hours after the beginning of balloon occlusion, 15 mCl of 99mTc-pyrophosphate was injected into the cranial mesenteric artery in 8 dogs and into a peripheral vein in 5. Gamma camera imaging of the abdomen followed three hours later. Four of 8 dogs injected intra-arterially showed positive images with full-thickness mucosal or transmural infarction. The 4 intravenously injected dogs with positive images had transmural infarction. Only minimal ischemic injury with superficial mucosal infarction was found in the 5 dogs with negative images. Tracer uptake per gram infarcted tissue was highest after intra-arterial injection. It was concluded that 99mTc-pyrophosphate allows external imaging of extensive intestinal infarctions after both intra-arterial and intravenous injection.

Animals↗
PubMed1978

Chronic vascular reactions to steel coil occlusion devices.

Original Gianturco steel coil vascular embolization devices and two modifications were compared for their occlusive effects and for the degree of adverse reaction in the surrounding vessel wall. Modifications consisted of silk or Ivalon replacing the wool strands of the original device. Single coils were placed into the left renal artery of nine mixed breed swine and restudied 3 months later. The bare coils did not occlude the vessels nor lead to significant foreign body reaction. Wool, silk, and Ivalon coils produced prompt and sustained renal artery occlusion. Upon histologic examination of the vessel wall, foreign body and chronic inflammatory reaction was found to be strongest against wool. This reaction was less with silk and markedly diminished with Ivalon. The results indicate that silk and Ivalon coils, while having the same occlusive effect, are preferable to wool coils if less local reaction is desired.

Alloys↗
PubMed1978

Protean manifestations of mycotic aneurysms.

Nine patients examined by arteriography were shown to have mycotic aneurysms involving the thoracic aorta, subclavian artery, renal artery, middle cerebral artery, hepatic artery, and splenic artery. Patients presented with sepsis, chest pain, mediastinal mass, headache, hypertension, and intraperitoneal bleeding. Etiologic factors included endocarditis, septicemia, drug abuse, and poorly controlled soft-tissue infection. Most mycotic aneurysms were virulent processes with rapid progression and only three of the nine patients (33%) survived. Since mycotic aneurysms may be associated with rapid progression and poor prognosis, early recognition is mandatory.

Adolescent↗
PubMed1977

Therapeutic embolization with long-term occluding agents and their effects on embolized tissues.

The effects of long-term occlusion of branches of the celiac and renal arteries were studied in 13 pigs, using isobutyl 2-cyanoacrylate (ibc), the Gianturco-Anderson-Wallace wool coil, and lvalon. IBC permanently occluded 2- to 8-cm lengths of both vessels, including their branches so that collateral circulation was not able to preserve the tissue supplied by the occluded artery. Gastric ulcers, splenic and hepatic infarcts, and large, sterile biliary cysts were observed on postmortem examination. Permanent occlusion was also observed with the wool coil and lvalon, but the pathological results were much less deleterious. The authors conclude that IBC is presently unsafe for use in branches of the celiac artery.

Angiography↗
PubMed1977

Control of variceal bleeding by superior mesenteric artery vasopressin infusion.

Liver function and clotting tests were evaluated in 39 patients with variceal bleeding prior to superior mesenteric artery vasopressin infusion. In six patients with mild hepatic dysfunction (Child's class A), permanent control of hemorrhage was achieved in all six and all survived the hospitalization. In 21 patients with moderate dysfunction (Child's class B), permanent control of hemorrhage was achieved in 13 (62%) and temporary control for 24 hr or longer in the remaining eight (38%). Survival in class B was 67% (14 of 21). In only four of 12 patients with severe hepatic dysfunction (Child's class C) was control of hemorrhage achieved (33 percent). None of these patients survived. Therapeutic failure also was associated with clotting derangements and the initial bleeding rate. It is concluded that the effectiveness of vasopressin in variceal hemorrhage is a function of the underlying liver disease and derangements in clotting function.

Adult↗
PubMedDate not supplied

Quantitative digital subtraction arteriography with a calibration catheter.

Quantitative intraarterial digital subtraction arteriography (DSA) was performed using a calibration catheter with three distal metallic ring markers. The two outer markers were 50 mm apart, and the third marker was in the middle. Measurements of 54 vessel diameters of the abdominal aorta, renal, lumbar, and iliac arteries were performed in a comparison study with direct film arteriograms in 10 aortofemoral runoff studies. Diameter measurements were made by both the observer on hard copy DSA images and by a computer using modified semiquantitative software. Against measurements on film, which were used as the standard, deviation in measurement on digital images varied from 8 to 13% for arterial diameters less than 5 mm and from 2 to 6% for diameters greater than or equal to 5 mm. Projectional artifacts caused 3% or less error. Knowing these variations in measurement is important in order to determine error tolerances for clinical applications. The calibration catheter serves as a convenient internal marker for DSA.

Angiography, Digital Subtraction↗
PubMedDate not supplied

Triple catheter aortoiliac angioplasty in a patient with a horseshoe kidney: technical note.

A method is described for protecting a nonstenotic anomalous artery to the left-lower pole of a horseshoe kidney that originated from a stenotic left common iliac artery. Using a triple catheter technique, injury to this anomalous renal artery was prevented while using "kissing balloons" to dilate bilateral proximal common iliac artery stenoses.

Angioplasty, Balloon↗