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Biomedical subjects

K H Albrecht

Publications and source records attributed to K H Albrecht.

44 records · Page 3Linked to original sources
PubMed1976

Method for simultaneous determination of red cell and plasma flow velocity in vitro and in vivo.

A method is described which can be used to simultaneously determine the flow velocity of plasma and of red blood cells in small glass tubes in vitro or in living microvessels of the microcirculation. The principle of dual slit photometry is applied to the measurement of plasma flow by determining the passage time of a dye bolus across two photodetectors separated by a variable distance. Measurements performed both in vitro and in vivo indicate a significant difference (up to 85%) between cellular and plasmatic flow velocity.

Animals↗
PubMed1975

[Artificial respiration as treatment of postoperative complications after cardiovascular surgery: indication, technique, results (author's transl)].

From 1972 to 1974 524 patients underwent surgery with extra corporal circulation. 83 (15,8%) patients had to be postoperatively ventilated for a prolonged period or reintubed after a symptomfree interval due to anticipated or manifested complications. 31 (37%) out of these expired. There was no death due to the prolonged ventilation itself, shown by the group, in which the causes for the above treatment were others but respiratory failure or insufficiency. All patients of this group survived. Indications, technique and results are described and discussed.

Germany, West↗
PubMed1975

[Treatment of postoperative renal insufficiency after cardiovascular surgical procedures by peritoneal dialysis (author's transl)].

In 1972 and 1973 there have been 698 (351 with ECC) cardiovascular surgical procedures. 29 cases of renal insufficiency were seen in this group, 15 requiring peritoneal dialysis. There were only two survivors in the latter group. However none died due to renal insufficiency. The indication, technique, complications, results are discussed in detail.

Acute Kidney Injury↗
PubMedDate not supplied

Related function of mouse SOX3, SOX9, and SRY HMG domains assayed by male sex determination.

Sox genes encode proteins related to each other, and to the sex determining gene Sry, by the presence of a DNA binding motif known as the HMG domain. Although HMG domains can bind to related DNA sequences, Sox gene products may achieve target gene specificity by binding to preferred target sequences or by interacting with specific partner proteins. To assess their functional similarities, we replaced the HMG box of Sry with the HMG box of Sox3 or Sox9 and tested whether these constructs caused sex reversal in XX mice. Our results indicate that such chimeric transgenes can functionally replace Sry and elicit development of testis cords, male patterns of gene expression, and elaboration of male secondary sexual characteristics. This implies that chimeric SRY proteins with SOX HMG domains can bind to and regulate SRY target genes and that potential SRY partner factor interactions are not disrupted by HMG domain substitutions. genesis 28:111-124, 2000.

Amino Acid Sequence↗