Search PubMed⌕ Search

Biomedical subjects

K Gupta

Publications and source records attributed to K Gupta.

At least 145 records · Page 8Linked to original sources
PubMed1984

Polyarthritis with atypical keratotic nodular dermatosis or polyarthritis with multiple keratoacanthoma. A case report.

We report an interesting case of generalized papular and nodular lesions with central keratinous plugs and severe hyperkeratotic-acanthotic histopathology with arthritis in a 19-year-old male patient who had suffered from a similar disease 2 years earlier. Papules and nodules erupted a few days after the arthritis and this was noticed during both episodes. On healing, nodules fell spontaneously leaving behind insignificant hyperpigmented scars.

Adult↗
PubMed1983

An immunofluorescence study of anti-pancreatic islet cell antibodies in the spontaneously diabetic BB Wistar rat.

Sera from BB Wistar rats and Wistar control rats were evaluated for the presence of islet cell antibodies in a prospective study using an indirect immunofluorescence assay on pancreatic islet cell suspensions from cultured rat islets. Islet cell surface antibodies were detected in sera from all animals of the spontaneously diabetic BB Wistar rat colony. The antibody could be detected well before the clinical onset of the disease and was present throughout the course of study of all diabetic animals. Sera from control Wistar rats were negative when tested for this antibody.

Animals↗
PubMed1983

Distribution of taurine in the crystalline lens of vertebrate species and in cataractogenesis.

Marked heterogeneity was observed in the distribution of taurine in different regions of the lens in various species. In general low taurine pools were observed in the nucleus of all species except frog and human. The distribution of taurine in human senile cataractous lenses at different stages of maturation showed decreased contents in all the regions except capsule epithelium as compared to the normal human lenses. This decrease is progressive upto the 'mature' stage of cataract. In rat lenses with galactose cataracts taurine contents decreased by about 83-94% of the normal values in the equatorial, anterior, posterior cortical and nuclear regions.

Animals↗
PubMed1983

Studies on synthesis and uptake of taurine in rat lens in vitro.

The occurrence of large taurine pool sizes in the crystalline lens was further elucidated by studying the in vitro synthesis and uptake of taurine in the rat lens. It was observed that a time- and concentration-dependent synthesis of taurine from methionine occurred in the rat lens. The time curve for uptake was linear up to 4 hr and was not saturated up to 40 mM concentration of taurine. The uptake was inhibited by ouabain, cyanide, Ca2+, GTP and cGMP but was not affected by ATP and cAMP. It is suggested that a dual mechanism exists for maintenance of high concentrations of taurine in the lens. Moreover, the uptake mechanism is energy-dependent.

Adenosine Triphosphate↗
PubMed1983

Pilomatrixoma.

Explore the source record for details and available documents.

Adolescent↗