[Reliability and importance of TPHA (author's transl)].
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Biomedical subjects
Publications and source records attributed to K Graf.
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The Minnesota Multiphasic Personality Inventory (MMPI) was administered to 66 non-narcotic drug abusers as part of an intensive study of polydrug abuse. Patients were classified into four primary drug-of-abuse groups using either stimulants, barbiturates, other sedative-hypnotics, or a combination of these drugs. It was readministered to 42 of these patients after 2 weeks' hospitalization. At admission, the group's MMPI profile was consistent with psychosis. At discharge, most of the MMPI T-scores were sharply reduced, and the groups' profile was consistent with sociopathy. The admission MMPI profiles of the four primary drug-of-abuse groups did not differ. At discharge, the stimulant group's profile remained psychotic, while the profiles of the other three groups were not psychotic. Such results raise the possibility of a toxic psychotic effect of chronic non-narcotic drug abuse. The group of stimulant abusers appeared schizophrenic, while the other groups of non-narcotic drug abusers appeared sociopathic.
Prior to and after removal of the tonsils and adenoids at the ENT clinic in Lucerne, phoniatric and X-ray examinations were performed in 42 children with normal velo-pharyngeal closure. Prior to the operation the velo-pharyngeal closure took place against the adenoid tissue. The surface of contact and the inclinatation of the velum were dependent on the amount of hyperplastic adenoid tissue. The configuration and the mobility of the velum were more important for the post-operative velo-pharyngeal closure than the distance from the pharyngeal wall. 3 months following the operation the velum was reaching the posterior pharyngeal wall. A distinct Passavant ridge was only visible in cases having slight difficulties in the post-operative adaptation of the velo-pharyngeal closure.
Longoperidol/Janssen, an orally administered neuroleptic with a five- to seven-day duration of effects, was clinically tested in six mental hospitals in the G.D.R. where the agent was administered to subjects of chronic to subacute schizophrenia. It was not possible for fully consistent results to be obtained in these tests. Workers at mental hospitals in Leipzig and Mühlhausen recommended that the drug should be imported, whereas those at the four other centers (Dresden, Halle, Jena, and Schwerin) did not consider the medication to be indispensable, although they were also able to observe the good effects of the agent.
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