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Biomedical subjects

K Goto

Publications and source records attributed to K Goto.

At least 1,045 records · Page 58Linked to original sources
PubMed1975

Involvement of central nervous system in pseudoxanthoma elasticum.

A 24- year-old female with typical pseudoxanthoma elasticum of the skin, angioid streaks of the optic fundi and cardiovascular involvement developed neurasthenic symptoms, epilepsy, progressive mental deterioration and focal neurological deficits. Cerebral angiography revealed marked generalized arteriosclerotic change and occlusion of the left internal carotid artery. The literature of pseudoxanthoma elasticum is reviewed with special reference to central nervous system (CNS) manifestations. The possible role of the involvement of cerebral arteries in the genesis of CNS manifectations is discussed. And the importance of neurasthenic syndrome as an initial sign, which suggests that CNS involvement has already started in this disease, is stressed.

Adult↗
PubMed1975

Evaluation of the significance of scintillation angiocardiography for determination of the left ventricular volume.

A method for the determination of the left ventricular volume by scintillation angiocardiography following a peripheral venous injection of a radioactive isotope was described. Salient points in its methodology were as follows: 1. This volume study was composed of non-gated scintillation angiocardiography and cumulative gated scintiphotography. 2. The non-gated scintillation data were stored into video recording system. 3. The gated scintiphotography was performed during a play-back of non-gated scintillation data, opening the gate at desired points of time during a cardiac cycle. 4. The left ventricular scintillation image was photographied in life-size on x-ray film by superimposing, 10-20 times, the gated image of the several consecutive heart beats during the "left ventricular phase" of the dilution of intravenously injected radionuclide. For validation of this method, the stroke volume obtained with this method was compared with that obtained by precordial radionuclide dilution curve recordable during the non-gated scintillation angiocardiography, and also with that obtained by non-simultaneous radiocardiography. It was concluded that the present method may be sufficiently accurate for clinical use.

Adolescent↗
PubMed1975

Transplantable adenocarcinomas from color-rectal tumors induced by infusion of N-methyl-N'-nitro-N-nitrosoguanidine in ACI/N rats.

Two transplantable strains of adenocarcinoma were established from the carcinomas of the colon and rectum induced by infusion of N-methyl-N'-nitro-N-nitrosoguanidine in inbred ACI/N rats, The tumors are solid type, not converted to ascite form yet, either papillary or tubulo-papillary adenocarcinomas, and particularly grow slowly, showing 2 to 4 months of survival in animals transplanted subcutaneously. Besides histological resemblance of the tumors to human adenocarcinoma of the large intestine, marked mucin production in tumor was noted in one of these strains.

Adenocarcinoma↗
PubMed1975

[Catheter cerebral angiography in little children. Review of 71 examinations on 59 children under the age of 7 years (author's transl)].

Although the role of the cerebral angiography in the diagnosis of the central nervous system disorders in children is well established, there exists some reluctance to perform angiography in little children, probably due to technical difficulties and possible occurrence of side effects. For the last several years, we have performed catheter cerebral angiography on children with various disorders of central nervous system utilizing Seldinger's transfemoral technique. Our technique has been described in detail with special reference to the dilator catheter and double replacement technique, and the results of 71 catheter angiographies on 59 patients under the age of 7 years have been reviewed. No neurological complication or systemic reaction to contrast medium was noted. Circulatory disturbance at the site of femoral puncture was occasionally noted. Transient circulatory disturbance of several hours' duration was not uncommon in this age group. There were three cases which developed thrombus formation at the puncture site with resultant successful thrombectomy utilizing balloon catheter. The causes of these complications were analysed, and the need for systemic heparinization or heparin coated catheter during catheterization in little children was stressed. Comparison was made with other methods of cerebral angiography applied to children. It has been pointed out that this is a relatively convenient and safe technique applicable to little children, in whom multivessel study is often needed.

Age Factors↗