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Biomedical subjects

K Geboes

Publications and source records attributed to K Geboes.

At least 271 records · Page 15Linked to original sources
PubMed1978

Submucosal tumors of the colon: experience with twenty-five cases.

Submucosal tumors of the colon are rare and require alertness on the part of the physician for early diagnosis. These tumors may not cause symptoms before attaining large size. In most cases the clinical histories are atypical. Because of the possibility of malignancy, adequate diagnosis and treatment are necessary. This report deals with 25 cases of submucosal tumors of the colon. The tumor series included seven leiomyomas, one granular-cell myoblastoma, two leiomyosarcomas, seven carcinoid tumors, six lipomas, one lymphangioma, and one neurofibroma. Five of the tumors were asymptomatic. The endoscopic appearances of the tumors, although not diagnostic, may give some indications as to their natures. Endoscopic removal is possible, although it is indicated for high-risk patients only. Because submucosal tumors may be malignant, and because differentiation from secondary tumors (metastases) or tumor-like lesions is difficult without histologic examination, complete removal of the tumor is the treatment of choice.

Adult↗
PubMed1978

Carcinoma of the liver: cytopathologic diagnosis.

Primary cancer of the liver is a rare disease, especially in countries with temperate climates. It is reported to be found in only 0.3% of all autopsies in these countries. An exact diagnosis is not always easy, especially in the elderly. In three aged patients, cytologic examination of material obtained from the liver by aspiration after puncture with a thin needle, indicated the diagnosis. Cytologic examination of aspirated liver tissue, although it can never be a substitute for biopsy, may be very useful not only in diagnosis but in monitoring the treatment of obstructive jaundice in elderly patients.

Aged↗
PubMed1977

Gastrointestinal disorders in old age.

399 elderly patients were studied in order to establish the frequency of different gastrointestinal diseases and to see to what extent gastrointestinal problems influenced the clinical picture and the final outcome. 276 patients were hospitalized because of medical emergencies. 123 patients were chronically ill. In the first group, 26.8% (74) had major gastrointestinal problems. In 42% of the remaining patients, important functional or organic gastrointestinal disorders were present. In the second group, 46% of the patients had gastrointestinal diseases. Lesions of the digestive system are an important cause of morbidity and mortality in the aged.

Age Factors↗
PubMed1977

Reactivation of tuberculosis in old age.

Reactivation of tuberculosis in old age has been reported by several authors. This article confirms these findings and presents another 5 examples. Lack of adequate chemotherapy during the first clinical episode may be an important factor in reactivation, especially in debilitated patients.

Adult↗
PubMed1977

Yersinia enteritis and enterocolitis: gastroenterological aspects.

The clinical, radiological, and endoscopic aspects of Yersinia enterocolitica infections in man were studied in a group of 37 adult patients observed in a 4-year period in a single gastrointestinal unit. The diagnosis was based on isolation of the bacterium in all but 1 patient. Abdominal pain and diarrhea were the most prominent symptoms, occurring in 80% of the patients. A syndrome simulating appendicitis was observed in 40%. The duration of symptoms before diagnosis varied from 1 or 2 weeks in 32 patients to several months in 5. On radiological examination the terminal ileum was involved over a distance of 10 to 20 cm in 21 of 24 patients. A coarse, irregular, or nodular mucosal pattern and pictures suggestive of ulcerations were the most prominent and early radiological signs. Endoscopic observations in 13 patients with marked diarrhea showed signs of colitis in 6 and aphthoid ulcers in 2 patients. On pathological examination, ulcerations and a nonspecific acute inflammatory cell infiltrate were observed. Although treatment with tetracycline or chloramphenicol resulted in 4 to 6 weeks in the disappearance of most symptoms and signs, pictures of "follicular ileitis" persisted for several months.

Adolescent↗
PubMed1976

Serum lysozyme levels in Crohn's disease and ulcerative colitis.

Serum lysozyme levels were determined in healthy volunteers, patients with Crohn's disease, and patients with ulcerative colitis. The mean concentration in Crohn's disease was significantly greater than in the other groups. In patients with Crohn's disease, as well as in patients with ulcerative colitis, the lysozyme levels correlated with the severity of the disease process and with the extent of the lesions: the more severe the disease and the more extensive the involvement, the higher the lysozyme levels. However, the lysozyme values of the different groups overlapped considerably. Our results indicate that lysozyme determinations have only limited discriminative value for the diagnosis of Crohn's disease and for determining the severity and the extent of the disease process in the individual patient.

Adolescent↗